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TPS2

Victor ID 4606
Gene Name TPS2
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3636892
NCBI Protein GI 68468955
Locus Tag CaO19.3038
Genbank Accession AACQ01000017
Protein Accession XP_721536
Taxonomy ID 237561
Chromosome No 1
Gene Starting Position 212193
Gene Ending Position 214859
Gene Strand (Orientation) +
Protein pI 6.77
Protein Weight 94254.61
Protein Length 888
DNA Sequence 
>gi|68469012:212193-214859 Candida albicans SC5314 chromosome 1 Ctg19-10163, whole genome shotgun sequence
CATGGCACCCCAACAAGTAAATGCATTTTCAGCAAATGGTTCTATTCCTTCACCAAAAGAATTTGAAGGA
AAAGGTAAACTAAAATTGTCGGGAAGAATCCTTAATGTGATGACCTCATTGCCCTTGCAAATTATAAGTG
ATTACGACAATAAGACAGGACAGTATTACTGGGATGTTGAAACTGTACGTGGTAATTCAGCATTGTATTC
GTCGCAACATTTTCTTGCTGAGAACAAAGAATGGGAGACACATTTGATTGCTTGGACTGGAGAATTGATA
AACAAAAAGAAAGATACAAGTTCATTAACTGCGGACACATTGCAAGATGACCCATTGTATTTGGATGAAG
AAGATAAACTGAAGATCGAGAAAAAATTATGTGATGCCAGTGGCACTCCAAACATCCATCCCGTGTGGTT
ATTGAGACGTGATCAGGGAAGGTGGAGAAAATATGCAGAGAACGTTTTGTGGCCGGTATTCCATTATATT
CAGGGACAACCATCTGATGGTAAAGCTGAAACTGATGCTTGGCATGATTATGTCAAATTTAACGAAGCAT
ATTTGAACAAAATCAAGTCGGTTTATAAGCCAGGGGACATTATCTGGATACACGATTACTACTTATTGTT
GTTGCCCCAATTATTGAGAATGGAGTTCCCAAATGCATATATCGGGTTTTTCCTTCATGTCCCTTTCCCA
TCCTCGGAGTACTTTAGGTGTCTTTCCAAAAGATCGCAATTATTAGATGGTATGTTAGGAGCTGACAAGA
TTGGTTTCCAGTCGGACTCCTTCCAAAGACACTTTATTTCTTGCTGTGCTCGTGTTTTGGGCTGTGAGGT
TAACAGAGATTCTGTTTCTGCATATGGTACAACAATCTCGGTTGAGACGTTGCCAATTGGTATCGATACT
GAGAAAATTGAACATGATGCCTTTTCCAGTGAGCTTGGAGTTGAGGAGAAGGTGCAAGCATTAAAACAGG
TTTACAAAGGCAAGAAGCTTATTGTTGGTCGAGACAGATTAGACAAAGTGAGAGGGGTTATACAAAAATT
GGAAGGCTTCGAAATCTTTTTGGATATGTATCCGGAATGGAGAGAAACTGTTGTTTTGATTCAAGTTTCC
AGTCCAGGATACTCACACTCCGCCAATGTTGAAACCAGAGTTACGGAAATAATTTCTCGTATTAATTCCA
AATACGGTAACCTCAACCACACTCCCGTTTTGCATTACCAGATGAGAGTTGCCAAAGAAGAATATTTAGC
ATTGTTACGAGTAGCAGACTTGGCATTGATTACTTCTGTTAGAGATGGTATGAATACAACTTCTTTGGAG
TTTGTTATTTGTCAGAAATACAATAATTCTCCATTGATTTTGTCGGAATTCACAGGTACAGCCACTGTGT
TGAAAGATGCTATTATGGTCAATCCATGGGATTCTGTGGGTGTAGCAAAGACTATCAACGACGCATTGAT
GTTATCTACGAAGGAAAAGGTTTCTTTGGAATCAAAATTGTACGAGAAGGTCCTTTCAAACACTGTTCAA
AATTGGACATCTACGTTCATTTGCGATATCCTTTCTCATTCAATTGTCACACACAGTAACAGCTATACCC
CTGCATTAAATAGACCATTATTGTTGAATAACTACAAGGAGTCACAGAGAAGGTTATTTTTGTTTGATTA
TGATGGGACTTTGACCCCTATTGTCCAGGATCCTGCTGCAGCTATCCCTTCCGATAAATTGAATCGTATT
TTGGATGTTTTATCTTCAGATCCAAAGAATCAAATCTGGATCATATCTGGTAGGGATCAAGCATTTTTGG
AGAAGTGGATGGGAAATAAGAATGTGGGTTTGTCAGCAGAGCACGGATGCTTTATGAAGGATATTGGTTC
CAAGGAATGGGTAAACCTAGCAGCATCGTTTGATATGTCTTGGCAAGAGAAAGTCGATGATATTTTCAAG
TACTACACTGAAAAAACACCGGGATCAAATATTGAACGTAAAAAAGTAGCATTAACTTGGCATTACCGTC
GTGCTGATCCTGACTTGGGAAATTTCCAGGCAGAAAAATGCATGAAAGAATTGAATGATACAGTAGCCAA
AGAATATGATGTTGAGGTAATGGCTGGCAAAGCAAACATTGAAGTAAGACCAAAATTTGTCAATAAAGGT
GAAATTGTCAAGAGATTAGTTTTGCATCCACACGGAGCCAAACAAGAAAAGCATCCTACTGGACATTGCA
CAAAAGATATACCAATTGAAGAATTACCTGATTTTATGTTGTGTTTGGGAGATGATTTAACCGATGAAGA
CATGTTCAACTCATTGAATGAGATTAATAAGAAATGGAAAGGTGACAATCGCCCAACCAACAAGTTTGGG
TCTTATGGTGTTTATCCTGTTGCTGTTGGTCCTGCATCAAAGAAAACGGTGGCAATTGCACATTTGAACG
AACCTCGCCAAGTGTTAGAGACCTTGGGTTTGTTAGCAGGATTGGTATCTATATTTGAAAGTGCTGGTAC
AGTTGATTTAGATGATCGTGGTCACCTTGCCAATAGTGTGTCTTCCGAAAGATCAAAACATGCTGTATCT
AAGGCAGTATCTTTACGTAAAAAAGCTAGTCAAGAAAAAGAAATTGTAAAAGAAGATCCTACTAATGGTG
CCAAGTG
Protein Sequence 
>gi|68468955|ref|XP_721536.1| hypothetical protein CaO19.3038 [Candida albicans SC5314]
MAPQQVNAFSANGSIPSPKEFEGKGKLKLSGRILNVMTSLPLQIISDYDNKTGQYYWDVETVRGNSALYS
SQHFLAENKEWETHLIAWTGELINKKKDTSSLTADTLQDDPLYLDEEDKSKIEKKLCDASGTPNIHPVWL
LRRDQGRWRKYAENVLWPVFHYIQGQPSDGKAETDAWHDYVKFNEAYLNKIKSVYKPGDIIWIHDYYLLL
LPQLLRMEFPNAYIGFFLHVPFPSSEYFRCLSKRSQLLDGMLGADKIGFQSDSFQRHFISCCARVLGCEV
NRDSVSAYGTTISVETLPIGIDTEKIEHDAFSSELGVEEKVQALKQVYKGKKLIVGRDRLDKVRGVIQKL
EGFEIFLDMYPEWRETVVLIQVSSPGYSHSANVETRVTEIISRINSKYGNLNHTPVLHYQMRVAKEEYLA
LLRVADLALITSVRDGMNTTSLEFVICQKYNNSPLILSEFTGTATVLKDAIMVNPWDSVGVAKTINDALM
LSTKEKVSLESKLYEKVLSNTVQNWTSTFICDILSHSIVTHSNSYTPALNRPLLLNNYKESQRRLFLFDY
DGTLTPIVQDPAAAIPSDKLNRILDVLSSDPKNQIWIISGRDQAFLEKWMGNKNVGLSAEHGCFMKDIGS
KEWVNLAASFDMSWQEKVDDIFKYYTEKTPGSNIERKKVALTWHYRRADPDLGNFQAEKCMKELNDTVAK
EYDVEVMAGKANIEVRPKFVNKGEIVKRLVLHPHGAKQEKHPTGHCTKDIPIEELPDFMLCLGDDLTDED
MFNSLNEINKKWKGDNRPTNKFGSYGVYPVAVGPASKKTVAIAHLNEPRQVLETLGLLAGLVSIFESAGT
VDLDDRGHLANSVSSERSKHAVSKAVSLRKKASQEKEIVKEDPTNGAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CaTPS2 mutant is attenuated in a mouse model of systemic infection (Van et al., 2002).
References
Van et al., 2002: Van Dijck P, De Rop L, Szlufcik K, Van Ael E, Thevelein JM. Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation. Infection and immunity. 2002; 70(4); 1772-1782. [PubMed: 11895938].