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CaRAS1

Victor ID 4602
Gene Name CaRAS1
Sequence Strain (Species/Organism) Candida albicans wo1
NCBI Nucleotide GI 6103364
NCBI Protein GI 6103365
Protein Accession AAF03566.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name Ras homolog type A
Protein Note Rasp type A
DNA Sequence 
>gi|6103364|gb|AF134251.1| Candida albicans Ras homolog type A gene, complete cds
GATCTAAATATATCTGTTGAATAGTAGCAGCCGGAATCGGTGGTGATGGCGATGGTGGTGGTGATGGATG
TAAATATGACAATCCCTCCCTAACCCCAGTAAAATCACTCATGACAAGAATTAAACACTAAATTTTCTCA
AACATTCTTCTGTTAATATATTACTACAAAAACACTTATTAATCGATTATTTTAGTTATTAAAATACCTC
TCTCTTTTAGTTATTGTCGAAAATAAATAGTTTATAGGGTTAATGAATGGAATGGCTTGCTTATTAATTC
TTGCTCTATATGAATAATTTTACACCCCCTTTCTCTTTTAGTAGTAGCAATATTTTTCTTCTTCTTCTTC
TTCTTTTGTTGAAAAATTTTCTTTCCTCTTTTCATATCTCGTCTGTTTTTCCTTCTTCATAAAAATAGAG
CTTTAATTCCTTTCTTTTTTTACATCAATCTATTCTTATTCTTATTCTTATTCTTATTCTTATTCTTATT
CTTATTCTTCTAGTTTTGATTAATTGGACATTGACCTTGATTTTTGTTTCAATTGACTAGATATAAACTC
TTCAATTATCATTAATATTAGATATAATCAAAGAAATCAAAAAGAAACCCCGGGCAAACACAAATTCATA
TCCACACATATACATACCATGTTGAGAGAATATAAATTAGTTGTTGTTGGAGGAGGTGGTGTTGGTAAAT
CCGCTTTAACCATTCAATTGATTCAATCCCATTTTGTTGATGAATATGACCCAACTATTGAGGATTCTTA
TCGTAAACAATGTACTATTGATGATCAACAAGTATTATTGGATGTTTTAGATACTGCTGGACAAGAAGAA
TATCTGGCCATGAGAGAACAATATATGAGAACCGGTGAAGGGTTTTTATTAGTTTATTCTATTAATTCAT
TAAATTCTTTCCAAGAATTAAATTCATTTTATGATCAAATTTTACGAGTCAAAGATTCTGATAATGTTCC
AGTTTTAGTTGTTGGTAATAAATGTGATTTAGAAATGGAAAGACAAGTTAGTTATGAAGATGGATTAGCA
TTGGCTAATTCTTTCAATTGTCCATTTTTAGAAACTTCTGCTAAACAAAGAATTAATGTTGAAGAAGCAT
TTTATGGATTAGTAAGAAATATTAATCAATATAATGCTAAAATTGCTGAAGCTGAAAAACAACAACAACA
GCAACAACAACAACAAAATGCAAATCAACAAGGTCAAGACCAATATGGACAACAAAAAGATAATCAACAA
TCACAATTTAATAATCAAATAAATAATAATAATAATAATACTAGTGCTGTTAATGGTGGTGTAAGTAGTG
ATGGAATAATAGATCAAAATGGTAATGGAGGTGTTTCTTCTGGTCAAGCAAATCTTCCAAATCAATCACA
ATCACAAAGACAACAACAACAGCAACAACAAGAACCACAACAACAATCTGAAAATCAATTTTCTGGTCAA
AAACAATCTAGCTCTAAATCAAAGAATGGATGTTGTGTTATTGTTTGAGCTAACTAAAAAGTTCTCGTAT
TTTTATCTATCTATTTACCTATCCAATTGATTGTTTCCAAGTTACGTTTTTATTTTCAACCTTCCTTCCC
CCCCCCATCATTGTAATTCATATAATCATTAAAAAAATGGGAGAAGATGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CaRAS1 mutant is less resistant to phagocytosis and has reduced virulence in mice (Leberer et al., 2001).
References
Leberer et al., 2001: Leberer E, Harcus D, Dignard D, Johnson L, Ushinsky S, Thomas DY, Schröppel K. Ras links cellular morphogenesis to virulence by regulation of the MAP kinase and cAMP signalling pathways in the pathogenic fungus Candida albicans. Molecular microbiology. 2001; 42(3); 673-687. [PubMed: 11722734].