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NRG1

Victor ID 4601
Gene Name NRG1
Sequence Strain (Species/Organism) Candida albicans ATCC10261
NCBI Nucleotide GI 12958591
NCBI Protein GI 12958592
Protein Accession AAK09366.1
Other Database IDs ATCC:10261
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name Nrg1
Protein Note zinc finger DNA binding protein; repressor of hyphal development; putative Tup1 targetting protein
DNA Sequence 
>gi|12958591|gb|AF321521.1| Candida albicans Nrg1 (NRG1) gene, complete cds
CTTTAGGGAAGACCTAGCAATATCATTCTCCACCATTGTTGAAAATTAAGAAATTGTACCACTAATAGAA
AGCTTAGTTTGCCCAAAGTCCACTATAGCATTATATTTGGTAACAGACTAGAGGGAACACACCATTTTGC
CGTTATTTCCAAAATTACCAAGCTCATTTAACTTCCATGAATAGTTAATTATGTAGATTGGTTTAAAATA
ATCTCAATGCAATTAACAACATGCGAAAAAAAATAATCTCTGCAAGAGATACAAAATAAAAATTAGCACT
CAAATTTGGCACATAGCCATGCATTAGCCTACCTACATATATCTGTATAATGTATTAATTACTTTTTTTT
TTGTTGCACTTTTGTATAATTATGAATTTTCCTTGATTGTTGTTTGTTGCATTTTAGTTTTAGTTTTATT
TTTTGAAGTCACAAATTGTGAGCTTGGAAAAATGCCTTCATGGGATTTTGTGTAGTTTTTTACTTTAACA
ATTAAAGCCTAAAAATAAAAAAAAAATCGTGATTTCTTTTTAATTTTGTTGTTATTTGTGTAATCTAAAT
GAATTTCAAGTAGTGCTCACTATACTTGAGTTTTCCCTTTTTTACACATATACCTAACAAGCTAGCAATG
AACCAAACGGTATAAAGACATGAAGATTTCCCTCTTCTTTTTGAGCGAGTTCGTTTTGGATTTTTCGATT
TCCTTTTCCTTTTTCTTATTATTATTATTATATCTACATATACCAACTAGGGATTGATCATTATAATTAA
CCCCTCCTTGCTTTCATCTTGTTTGTCACAGACGTTACACATTAAGAACTGTTATAATAAACGTCCAGGT
TACTATTTTCCAATATTATATTTTTGTTTTTGCTGCTAAATAATTTAACTGAAGTGAATTTTCTTTATTT
CAATATTATACTTAATTGCAAAAAAAAAAAAAATAGAGAGAGAAAAAAAAAATCATCAGCTTTCTTATTA
TTTACAACTGAGAATTAAAAATATCAAAAATAATCCTACTATCAGTTATTATATACTAGGATTTGTTATT
ACAATTTGCTTTACAAGAGAACCTCATTGTTCAAGTATCTTCCAGAATCTGAAACAGGTATTATATAAAT
AACAATAAAACATCGTTATCCTGTTTCTCATCTCAAAATTTTTCCCTGCTAGTTTCATTAAGAATCAAAC
AATCATTATGCTTTATCAACAATCATATCCAATAACAAATAAGTTATTAAATGCTAGTGCTGCTGGTAGT
ACATCCACAGCTTCTATAATTGACGGTGGTTGCACGTTGTCGAAACCTGGCAGTGGAAAAACAAAATCAA
CAACTTCGTTACCTTCGTTTAACGAACTTCTTACTTCCATTCCATTGCCAAATGAATTCAAACCATCAAC
CAACAATACCAACCAAGCAGCAGCAGCAACAGCAACATCTCCTTATAACTACTATATGGGACCACCAGCT
CAACATCGTTTACCAACACCACCACCATATCCAATGAGCTCGCCAACAACAGCAACAGCAGCTACTCCAT
TGTCACAACAATCACCTCACTTGCAACCCCAACAAACACTACAACAACCTCAGCCATACCATCAACAATA
CTACAACTATCAGTATGCTGCTCCTCCTTATCCCCATCTTTCCCAAGTACCTCCACCAGCATCATATCAA
CAACGTCACCAACAACCCATGTACCAAAACACTAATGGAGTACCGATTATAATCAGACCATCTCCAGGGC
TAATTACTCCTACATCGACTACTTTTGATCATGCCAAAATACGGTCAAACTCTACTGGTGATTTACTGGC
CAACTCCCTTGCTTTGTCGTCAAACAATAACACCCAAAGCAAAGACCCAAGAAGAAAACACGTCTGCAAA
GTGTGTTCGAGATCGTTTACTACTTCAGGACATTTAGCTAGACACAATCGTATCCATACTGGAGAGAGAA
AACACCAATGTCCATGGCCAACATGTGAAGCCCGTTTTGCTCGTCAAGATAATTGTAATCAACATTACAA
GACTCATACCAATGGGAAAAACAAACGCAACAGACAACAACACAGGACTTTAGAAGCTTCACATGTTGGA
ACAAAATACAACACCAAGAGCCTAGTATAGATGTGGTCAAAATTGTATTATAAAACGGGTTAAATTTGGA
TGGTTAATTGCTTGGGTTTAGTTTTTTTTTGTTATGGTTACTGGTTCATGTATAGGTTCTTTTTCTAATA
TACTTTTACCTCCAAATATAGTACTGCCTAGTCTCTACCCCTTTTGGTGCTACATT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Inactivation of CaNrg1 causes attenuated virulence in mice (Murad et al., 2001).
References
Murad et al., 2001: Murad AM, Leng P, Straffon M, Wishart J, Macaskill S, MacCallum D, Schnell N, Talibi D, Marechal D, Tekaia F, d'Enfert C, Gaillardin C, Odds FC, Brown AJ. NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. The EMBO journal. 2001; 20(17); 4742-4752. [PubMed: 11532938].