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virB from Shigella flexneri 5a

Victor ID 46
Gene Name virB from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876516
NCBI Protein GI 13449069
Locus Tag pWR501_p130
Protein Accession NP_085285.1
Other Database IDs UniProtKB-ID: VIRB_SHIFL
UniRef100: UniRef100_P0A247
UniRef90: UniRef90_P0A247
UniRef50: UniRef50_P0A247
UniParc: UPI0000000B47
EMBL: X14340
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: CAA32525.1
EMBL-CDS: CAC05798.1
EMBL-CDS: AAK18441.1
EMBL-CDS: AAP78986.1
EMBL-CDS: AAL72295.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093070
EnsemblGenome_TRS: EBESCT00000094026
EnsemblGenome_PRO: EBESCP00000090233
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 98816
Gene Ending Position 99745
Gene Strand (Orientation) -
Protein Name transcriptional activator
DNA Sequence 
>gi|13448939:98816-99745 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TTTATGAAGACGATAGATGGCGAGAAATTATATCCCGAATAGCTTCATCTATTTCTCTCTGAACTGTTTT
GTTTATTTTAGATAATGTAAATATTAGAGTTCTGTTTGTTTTATTCTCTTTTCTTTTTATGTAAGTCCGT
TTGTCTTTAGAAATAAATAACGAGTCAACTTTTAGCGAAGGGTTTTGCTTTCTGTTTTTGCTTTTCTTTA
TGATGTTTAAAATTTCTTTTTTATATATGTCCGGGGGCAGATTTGTATCAAGGTCTTTTATTTCTTCCTT
TAATATTGGTAGTGTAGAACTAAGAGATTCATTAGCCTTTTCAAGTCCTTTATAATAATTGAATAATATC
TTGTAGTCATTAAAGTTAAGTTCTGACGCGATTGGAAATAGAGATATTATTTCCTGTGGAACGCTTGCTG
CCTGAAAGGCACGAGTGACTTTCGCGCGAGACAGATTCTCTTTTTTGGCTATGTCTTTATAGGACATCCC
TGATACTTTCAGAAAATTAAGACCAATACCAAGTTCTCGGATGCTATGCTCTTTTGCTGTTTGTATATCG
TTTGCTAGTTTTCTGGCATCAAGAGTAGATATATATTCTTTTGAATATAGAACTTCAAGATCTGCTCCTG
CATATATTGCAGATGCTCTTCTACGAGTGCCATCCAGAATTTCAATTCTACCATCAATCTCCCTTCCTAT
TACAGGGAAGAATTGTTGTAGCTTTATAGTTTTTATGATATCGGCTAGTGATTCTTCTGTTAGGGATTCT
TGATCGCGTACATTCGTTTTTTGGTTGACGAAGGTTAAATCTTGGATCCTTTTATGAGGAATCTTGGCTT
TGATAAAGGAAACTTTATTACCAGAATGGAGTGTAAACTCTTTCTTTTGGCCTTCCTTTATACTTAACAA
GTCGTTGCACAAATCCACCA
Protein Sequence 
>gi|13449069|ref|NP_085285.1| transcriptional activator [Shigella flexneri 5a str. M90T] MVDLCNDLLSIKEGQKKEFTLHSGNKVSFIKAKIPHKRIQDLTFVNQKTNVRDQESLTEESLADIIKTIKLQQFFPVIGREIDGRIEILDGTRRRASAIYAGADLEVLYSKEYISTLDARKLANDIQTAKEHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIISLFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPPDIYKKEILNIIKKSKNRKQNPSLKVDSLFISKDKRTYIKRKENKTNRTLIFTLSKINKTVQREIDEAIRDIISRHLSSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virB mutants have an avirulent phenotype and do not invade host cells (Sasakawa et al., 1993).
References
Sasakawa et al., 1993: Sasakawa C, Komatsu K, Tobe T, Suzuki T, Yoshikawa M. Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. Journal of bacteriology. 1993; 175(8); 2334-2346. [PubMed: 8385666].