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ASH1

Victor ID 4589
Gene Name ASH1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3641249
NCBI Protein GI 68477667
Locus Tag CaO19.5343
Genbank Accession AACQ01000059
Protein Accession XP_717146
Taxonomy ID 237561
Chromosome No 2
Gene Starting Position 108516
Gene Ending Position 109865
Gene Strand (Orientation) +
Protein pI 10.19
Protein Weight 48927.14
Protein Length 449
DNA Sequence 
>gi|68477720:108516-109865 Candida albicans SC5314 chromosome 2 Ctg19-10225, whole genome shotgun sequence
TATGAGTTTAGTCCAGTCAGCCATGTTTAATCATCATATGGGCCCTTCACACACTAGATCTCGAAGTTTC
GAGTTATTCCAAGAAGCTAAAACCTTAAGGGTTGCTGCTTGTAAGAGATCATACAGCGACGATTTGAATA
TCAGCACTAAAAGAGCAAGAACTGCACCACCATCTCCTCCATATGAAACTGCTACACCCACCAGAGCTAG
TAGGTTGGTAATTTCAAATTTGGTTAAGCCAACAAGCAACTTAAGATCAAGATCGCTTTCTCCAAATAAA
AAGTTTTCCAGTCCGTTATCCCCATCGTCATCACCAATAGCGACTGTCACATCACCTATAAGCTCACCCC
AAAACATAAAGATAAAACTACCAAGTATTTCTGATGCATTAAATCTACCACCAATAACTTCTAAAGAGCC
AGTGAAATTGAAGCCAATTGTGCCAACAGTCTCATTAGATTATTTTGATACATACAAACCCAATGACGAA
AATTGGAGGTACGGGCTTTTGGATAAAATTGCCAAAGAATCAAAGCATTTCCACCTTAATCAATACAACT
ACCTTAATGACCATGCAAAACCAAGTTTTGACTCCAAACTAAGTTCGAAAATCCAACAACTGTCAATTGC
AAATGGAAAGAAAATAAATTTTCCCTACGAATCGAATTATACATATTTGAATAAAACATACTTGAACGAT
GTTAAAAACTATCCCGAATATCTAGAGTTGGCCGCCGAGTCATTATTACAATTGAAAGAGCGCCAACTCC
CCCCACCTCCATTACAGCTGCACCAAAAACAACACCCACCACCACCACCACACTTGCCAGTGCAAGGACT
TTTGCCTGTTCCAGCACCTCCGGTTTCACATTTTTCTTCTTCTTACACCACACCACAAGCCCCAACATTT
TACCACCCACCTTCACAACAACAACAACAGACTCCACCACCACAAACGCTACATCATCAACAACCACAGC
CACCTATTTCTACACACAAATTCATTCCAATATCACCTCCATCTGCTAAAAAATCTAGATCGGATTTATT
GAAATCACCACCAAAACACCATCATCATCACGCACCAAGGGTATGCATATCGTGTGGGTCAGACCAATCA
CCATGCTGGAGACCATCCTGGTCTATTAAACAAGGACAATTGTGTAATTCATGTGGGTTGAGGTATAAAA
AGACAAAGGCTAGATGCTTAAATGACAAATGTAAAAAAATACCTGCCAAGGGTGAATGGACCCTCATGCA
AAGCAAAGGAAAAGAGACTTTTGAAGATGGTATAGAGGGTTATAGCTGTATTGCATGTGGCTGGAGAGTT
GAAGTACTTCCTAAATCTTG
Protein Sequence 
>gi|68477667|ref|XP_717146.1| hypothetical protein CaO19.5343 [Candida albicans SC5314]
MSLVQSAMFNHHMGPSHTRSRSFELFQEAKTLRVAACKRSYSDDLNISTKRARTAPPSPPYETATPTRAS
RLVISNLVKPTSNLRSRSLSPNKKFSSPLSPSSSPIATVTSPISSPQNIKIKLPSISDALNLPPITSKEP
VKLKPIVPTVSLDYFDTYKPNDENWRYGLLDKIAKESKHFHLNQYNYLNDHAKPSFDSKLSSKIQQSSIA
NGKKINFPYESNYTYLNKTYLNDVKNYPEYLELAAESLLQLKERQLPPPPLQSHQKQHPPPPPHLPVQGL
LPVPAPPVSHFSSSYTTPQAPTFYHPPSQQQQQTPPPQTLHHQQPQPPISTHKFIPISPPSAKKSRSDLL
KSPPKHHHHHAPRVCISCGSDQSPCWRPSWSIKQGQLCNSCGLRYKKTKARCLNDKCKKIPAKGEWTLMQ
SKGKETFEDGIEGYSCIACGWRVEVLPKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ash1p mutant is attenuated for virulence in a mouse model of disseminated candidiasis (Inglis and Johnson, 2002).
References
Inglis and Johnson, 2002: Inglis DO, Johnson AD. Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans. Molecular and cellular biology. 2002; 22(24); 8669-8680. [PubMed: 12446785].