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FTL_1622

Victor ID 458
Gene Name FTL_1622
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3952010
NCBI Protein GI 89256899
Locus Tag FTL_1622
Protein Accession YP_514261.1
Taxonomy ID 119857
Gene Starting Position 1551963
Gene Ending Position 1553189
Gene Strand (Orientation) -
Protein Name multidrug transporter (tetracycline resistance protein)
DNA Sequence 
>gi|89255449:1551963-1553189 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
ATTATTGTACCCTTTCACGCAAGATTTTAATAGAAAATACAAAGATAATCGCTGCAATAAAATACATCCT
GCCACCAAATGAAATTGGCGAACTCGGAGATATTGATGCAAGATGTCCCATCATAATATCATTTAAAAAC
CAAGCTAAACCAAAACCTGCACCTGCAGCACCCATTGCTTTACCTTGTTCTTTATCTGTAACTGCACCTG
AAATCATTGCTAAAAGAGCTGTATAACAGATAAGTTGAGATGATGATAAAACTATTGTTAGCAACCATTG
TGCGATTTGATTAGTTAAAATAGCCACAAAAATAAAACCTATACCACAAACAACAGCAGCTCTTACAAAA
GCAACCTGATTAGATAATCTTGCAAAAATTACCGGCTGAATAATAATACTTGCAAGCGCTGTAGATAATC
CCATAAGAGCATAAAAGGCGCCCGTTTGTGAAACTGTATAGCTATAAGTTAGGTTTAAAAACAATGCTAT
ACCTTGACCATAAAAGCCCCACGCGCATTGTACTAGCAAATACACCACCCCAATTAATCTAACACGCTTA
TCAGATAATAAAAATGATATTGTCTTGTAGATTGTCGCAAGTTGAATAACCAAACCAGGATTCTTTGGTA
AATCTTTTGTCATGATAATAACTATAAAAATAATATTCAGCAGTGATAATACTGCTGCAAAGATAAACGG
TAAAGTATGACTAATATTCATTACTGAAACAAAACTTGTAACTATTGGACCAACCACAAAGCCTAAAGAT
GCTGCCATCGTAATATAGCCCAAATTTTTAGATTTATCTTCTTCTGTAGATATATCAATCACCGCAGCTT
GAGCAATTTCAAAAGCTCCTCCAGCTAACCCACAAACAAATCTACTTGCTACAAATAGTAGATAGTGATG
TGAGTATATAGCATATGCTGATAAAATATATGATACACATGTGGTTGATAAAGCAACGATTAGTATAATT
TTGCGTCCATATTTATCCGATAATTCACCAATAATAGGACAGCCAATCATTAATCCTAATGGCCAACATG
CTAAGGCTATCGAATAATACCAGTTCTGAAAGTTACTACCTGGATCACCAAAAGTAATACATGATTGTCC
AAAAAATAACGATGGCATAATAGGAAAAACAAGTCCCGCACCCATTATGTCTATGATAATTGTTGTAATA
AGTACCGGAATTAAAATATTTTTTGTACGCAATTTCA
Protein Sequence 
>gi|89256899|ref|YP_514261.1| multidrug transporter (tetracycline resistance protein) [Francisella tularensis subsp. holarctica LVS] MKLRTKNILIPVLITTIIIDIMGAGLVFPIMPSLFFGQSCITFGDPGSNFQNWYYSIALACWPLGLMIGCPIIGELSDKYGRKIILIVALSTTCVSYILSAYAIYSHHYLLFVASRFVCGLAGGAFEIAQAAVIDISTEEDKSKNLGYITMAASLGFVVGPIVTSFVSVMNISHTLPFIFAAVLSLLNIIFIVIIMTKDLPKNPGLVIQLATIYKTISFLLSDKRVRLIGVVYLLVQCAWGFYGQGIALFLNLTYSYTVSQTGAFYALMGLSTALASIIIQPVIFARLSNQVAFVRAAVVCGIGFIFVAILTNQIAQWLLTIVLSSSQLICYTALLAMISGAVTDKEQGKAMGAAGAGFGLAWFLNDIMMGHLASISPSSPISFGGRMYFIAAIIFVFSIKILRERVQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1622 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG2814G, under G: Carbohydrate transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].