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FTL_1275

Victor ID 456
Gene Name FTL_1275
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951959
NCBI Protein GI 89256584
Locus Tag FTL_1275
Protein Accession YP_513946.1
Taxonomy ID 119857
Gene Starting Position 1215644
Gene Ending Position 1216303
Gene Strand (Orientation) +
Protein Name dethiobiotin synthetase
DNA Sequence 
>gi|89255449:1215644-1216303 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGAAAAAGTTTTTTATCATTGGTACGAATACCGAAGTAGGTAAAACATATATATCAACCAAGCTTATT
GAAGTTTGTGAGCATCAGAATATTAAATCACTTTGTTTGAAACCTGTAGCGTCTGGACAAAGTCAATTTT
CAGAGCTGTGTGAAGATGTAGAAAGTATTCTAAATGCTTATAAGCATAAATTTACAGCAGCTGAAATAAA
TTTAATTTCATTCAATCAAGCAGTTGCTCCTCATATAATTGCAGCAAAAACAAAAGTAGATATTTCTATT
GAGAATCTTAAGCAATTTATCGAAGATAAGTACAATCAAGATTTAGATATTCTCTTTATTGAGGGTGCTG
GAGGATTATTAACTCCCTACTCAGATCACACTACCCAGCTTGATCTAATAAAGGCTCTGCAAATACCAGT
ACTACTAGTATCAGCTATAAAAGTTGGTTGCATAAACCATACCTTACTAACTATAAATGAGTTAAATCGT
CATAATATTAAATTAGCTGGTTGGATTGCTAATTGTAATGACTCAAATATCAAATACATTGATGAACAAA
TAAATACTATAGAAGAGCTATCAGGATATAAGTGTAGTGCAAAAATTTCTCGAAATGCTGATTATTTAGA
TTTTATAGATTTATCCAAGATACTAATATA
Protein Sequence 
>gi|89256584|ref|YP_513946.1| dethiobiotin synthetase [Francisella tularensis subsp. holarctica LVS] MKKFFIIGTNTEVGKTYISTKLIEVCEHQNIKSLCLKPVASGQSQFSELCEDVESILNAYKHKFTAAEINLISFNQAVAPHIIAAKTKVDISIENLKQFIEDKYNQDLDILFIEGAGGLLTPYSDHTTQLDLIKALQIPVLLVSAIKVGCINHTLLTINELNRHNIKLAGWIANCNDSNIKYIDEQINTIEELSGYKCSAKISRNADYLDFIDLSKILI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1275 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0132H, under H: Coenzyme transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].