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FTL_1273

Victor ID 454
Gene Name FTL_1273
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951957
NCBI Protein GI 89256582
Locus Tag FTL_1273
Protein Accession YP_513944.1
Taxonomy ID 119857
Gene Starting Position 1213798
Gene Ending Position 1214925
Gene Strand (Orientation) +
Protein Name 8-amino-7-oxononanoate synthase
DNA Sequence 
>gi|89255449:1213798-1214925 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGTTAAACCTACAAGATAAATATACTCAATATCAAAGAGATAATTTATTAAGAGAGTTAACTCTTTTT
ATAAAAGATGACTCTATTATAGATTTTACAACTAGTGACTATTTAAATCTATCATCAGCACACAACTTAA
AACATGCCATAGTAAATGGTTTTGATAAATATGGCTTTGGTAGTAAAGGATCTAATATAGTTTGTGGCTA
TACTGATGAGACACAACAGTTTGAACATGAGTTTGCAAAGTTTATTAACTATCCTAGAGCAATATTTTTT
AGTTCAGGTTTTATGGCAAATTTAGCAATTTATTCAACACTGTTTAGTAAACATGATAGTATCTTTGCAG
ATAAGTATATCCATGCATCTATTATTGATGGAATCAAGCTTTCACAAGCTAAGCTAAGAAGATATAAACA
TCAGCAATTAAGCCAACTTCAAGATATTTATGATGGTAAAAGTTTTATAACTACAGAAGGAGTTTTTAGT
ACCTCAGGATCAATTACTCAACTTGATAAGCTTGCTAAAATCACACCAGAAAAGCTTATAGTTGATGAAG
CTCATAGTTTTGGAGTTTTGGGTAAAAATGGTCGCGGTGCGATCAACAGCTTTCGAATAAGCTATAAAAA
TTGTCCAATCTGTGTTTTCCCTCTTGGTAAAGCATTTGGTGGAGTTGGTGCTGTGGTTTGTACTACAGAA
GCAATTGCAGAATATCTAATACAATTTGCGCGTAACTATATCTATACAACAGCATTACCACCAATGATAT
TAAAAGCTGCTTTAATACAACTAAAAAACCTTGAAAATGCTAATGATAATCGAGTAAGACTTCAGCAAAA
TATCACTTTTTTTAATGAGTTATGTGATGCTAAAGATCTTGAGTTAGTCTCTAAAGATTTATCTCCTATT
AGAAGTATTCAACTAAATAATGCTAATCTAGCAATTAGATTAAAAGATAAGCTCTTTGAGAATAAAATAA
TAGTATCTTGTTTTAGATATCCTACTGTACCTAAAGACCAAGCTATACTAAGATTTTCGCTACATAGTAA
TAATACTTTTGATCAGATTCAACAAGCTTTAGAAATTATTTCCAAAGAGGTTAAGTATGAGTATATACGA
TCAAATTA
Protein Sequence 
>gi|89256582|ref|YP_513944.1| 8-amino-7-oxononanoate synthase [Francisella tularensis subsp. holarctica LVS] MLNLQDKYTQYQRDNLLRELTLFIKDDSIIDFTTSDYLNLSSAHNLKHAIVNGFDKYGFGSKGSNIVCGYTDETQQFEHEFAKFINYPRAIFFSSGFMANLAIYSTLFSKHDSIFADKYIHASIIDGIKLSQAKLRRYKHQQLSQLQDIYDGKSFITTEGVFSTSGSITQLDKLAKITPEKLIVDEAHSFGVLGKNGRGAINSFRISYKNCPICVFPLGKAFGGVGAVVCTTEAIAEYLIQFARNYIYTTALPPMILKAALIQLKNLENANDNRVRLQQNITFFNELCDAKDLELVSKDLSPIRSIQLNNANLAIRLKDKLFENKIIVSCFRYPTVPKDQAILRFSLHSNNTFDQIQQALEIISKEVKYEYIRSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1273 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0156H, under H: Coenzyme transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].