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kerp1

Victor ID 4533
Gene Name kerp1
Sequence Strain (Species/Organism) Entamoeba histolytica HM-1:IMSS
NCBI Gene ID 3407934
NCBI Protein GI 67476017
Locus Tag EHI_098210
Genbank Accession DS571169
Protein Accession XP_653629
Taxonomy ID 294381
Gene Starting Position 8848
Gene Ending Position 9402
Gene Strand (Orientation) -
Protein pI 9.68
Protein Weight 20991.75
Protein Length 184
Protein Note transcript EHI_098210A
DNA Sequence 
>gi|183231175:8848-9402 Entamoeba histolytica HM-1:IMSS scf_1104750517789, whole genome shotgun sequence
GTTAATTTTCATAGAAAATATCTTTCTTTCCTTTCTTTGATTTTTTATCTAATAAGGCATCAGCCTTTGT
TTCTTTGTATTTTTCTTTCTTTTCTTCTTTAGGAGTAGGAGCTTCACCTTCTTCTTCTTCAAGCAAAATT
TTACCGTAGTTTTTAGTTTGTTTTGAAATTTTATTTTCTTCCAATGAACTAACTTTCTTATCATCTTTTA
CTTCTTTTTCTTCATCATTATTTTCATCATTAAGTCTTTGTTTTTTCTTTGGTTTCTTCTCTTTTACAAT
TTCTTTTTCTGCCTTCTTTTCCATTTTTAATTTCTTCTCTTCCATTTGTTTTTGCTTCTTTAATTCTTTC
TCTTCTTTCTTTAATTCTTCTTTTGTTTTTGATTCAGTCTTTAAAGGTGGTTGTGCATTAAGAATTGTGA
TAGTTTTATTTAATGCATTAGCTAATTCATTAATCATTTCAACTATCTCTTTTTCATTTTCATTTAATAC
TTCTTTTTTGAGAAGAGCTTGTGCTTTTCCTTGAATAGTATTTGTTGTGCTTATAATATTTTCCA
Protein Sequence 
>gi|67476017|ref|XP_653629.1| lysine and glutamic acid-rich protein 1 (KERP1) [Entamoeba histolytica HM-1:IMSS]
MENIISTTNTIQGKAQALLKKEVLNENEKEIVEMINELANALNKTITILNAQPPLKTESKTKEELKKEEK
ELKKQKQMEEKKLKMEKKAEKEIVKEKKPKKKQRLNDENNDEEKEVKDDKKVSSLEENKISKQTKNYGKI
LLEEEEGEAPTPKEEKKEKYKETKADALLDKKSKKGKKDIFYEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: parasites with blocked expression of kerp1 are attenuated in causing liver abscesses in hamsters (Santi-Rocca et al., 2008).
References
Santi-Rocca et al., 2008: Santi-Rocca J, Weber C, Guigon G, Sismeiro O, Coppée JY, Guillén N. The lysine- and glutamic acid-rich protein KERP1 plays a role in Entamoeba histolytica liver abscess pathogenesis. Cellular microbiology. 2008; 10(1); 202-217. [PubMed: 17711481].