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RabA

Victor ID 4532
Gene Name RabA
Sequence Strain (Species/Organism) Entamoeba histolytica
NCBI Nucleotide GI 2623646
NCBI Protein GI 2623647
Protein Accession AAB86482.1
Taxonomy ID 5759
Gene Strand (Orientation) ?
Protein Name rab-like GTP-binding protein
DNA Sequence 
>gi|2623646|gb|AF030184.1| Entamoeba histolytica rab-like GTP-binding protein (RabA) mRNA, complete cds
ATATCTCCTTTTAATTTAGCTCCACTTACATCAATAGCATTCAAATGACAAACTGGTCGTTGAATGATTT
TCATTAATCTCTTTACATCACTTGTACTTAAATCAACTCCTGCAACGTCTAATCTGTTAATTGGTGGGAA
TTTAACTAGACTAATCGGAGATGTGGGTGTTGGAAAAACTGCTCTAATTCAAAGATTTTGTTTTGGAACT
TATACAGAAGACTATGATGCAACAATTGGTATTGAGACATGTGACAAATCAGTAAACCTTGATGGTAAGA
TGTACCAACTACAATTATGGGATACTGCAGGACAAGAAAAATATCATTCATTAGTTAGATTATATTTCAA
AGACATTAAAGGAGTGTTGTTAGTCTTTCAAATTGATAGACAAGAGAGTTTTGACCATTGTAAAGACTGG
TTAGATCTATTTTACAGTAGCATTAGTTCAGGGTTTACTCCACCTGTATTACTTGTTGGAAATAAATGTG
ATTTAATTGGAAGTTCAACACGTGTTAGTAAAGAGTCTGTTGATCGGTTTGTCAGTGAAAATGGATTAGA
ATATATAGAAACAAGTAGTAAAGAAAATACAAATGTCCAAGAAGCTTTTTCACAACTACTTCGTTCTATT
ATCAATTTAAAACCTATTTTTGTTGATCCAGGTGAAGAAGAAGTAAAAATAACTCAACAAACAGAAGATA
CAGATGGTGGTTGTGTTTGTTAAAACTTTTTTTAATTTATTCAATGGGGTTTTCAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: EhRabA mutant has reduced adhesion and host cell lysis of CHO monolayers (Welter et al., 2005).
References
Welter et al., 2005: Welter BH, Powell RR, Leo M, Smith CM, Temesvari LA. A unique Rab GTPase, EhRabA, is involved in motility and polarization of Entamoeba histolytica cells. Molecular and biochemical parasitology. 2005; 140(2); 161-173. [PubMed: 15760656].