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mxiK from Shigella flexneri 5a

Victor ID 45
Gene Name mxiK from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876515
NCBI Protein GI 13449087
Locus Tag pWR501_p148
Protein Accession NP_085303.1
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 114210
Gene Ending Position 114776
Gene Strand (Orientation) +
Protein Name Type III secretion protein
DNA Sequence 
>gi|13448939:114210-114776 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TATGGGCATTCAAAACAGGGTGGTTCAAGAGAAACAAAATATGATAAGAATGGATGGAATTTATAAAAAA
TATCTTTCAATAATTTTTGATCCAGCGTTCTATATAAATAGAAATCGGTTGAATTTGCCTTCTGAACTGT
TAGAAAATGGCGTAATCAGAAGTGAGATTAATAATCTCATAATTAATAAATATGATCTAAATTGCGATAT
TGAACCTTTAAGCGGGGTAACCGCTATGTTTGTTGCCAACTGGAATTTACTTCCAGCTGTTGCTTATTTT
ATCGGTAGTCAAGAGTCTCGGTTAATTAATCATAGTGAGATGGTTATTAGTTATTATGGGGGCAAAATCA
GTAAGCAAGGGGAGGCCGCTATTCGAAGTGGTTTTTGGCATCTTATTGCGTGGAAGGAAAATATATCTGT
TGGTATATATGAAAGAATAAACTTATTATTTAATCCAATTGCTTTGGAGGGAAATTATACGCCTGTAGAA
AGAAATTTGTCCCGATTAAATGAAGGTATGCAATATGCAAAAAGGCACTTTACCGGTATCCAGACATCAT
GCCTATG
Protein Sequence 
>gi|13449087|ref|NP_085303.1| Type III secretion protein [Shigella flexneri 5a str. M90T] MGIQNRVVQEKQNMIRMDGIYKKYLSIIFDPAFYINRNRLNLPSELLENGVIRSEINNLIINKYDLNCDIEPLSGVTAMFVANWNLLPAVAYFIGSQESRLINHSEMVISYYGGKISKQGEAAIRSGFWHLIAWKENISVGIYERINLLFNPIALEGNYTPVERNLSRLNEGMQYAKRHFTGIQTSCL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiK mutants are unable to invade HeLa cells (Jouihri et al., 2003).
References
Jouihri et al., 2003: Jouihri N, Sory MP, Page AL, Gounon P, Parsot C, Allaoui A. MxiK and MxiN interact with the Spa47 ATPase and are required for transit of the needle components MxiH and MxiI, but not of Ipa proteins, through the type III secretion apparatus of Shigella flexneri. Molecular microbiology. 2003; 49(3); 755-767. [PubMed: 12864857].