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pyrF

Victor ID 4498
Gene Name pyrF
Sequence Strain (Species/Organism) Pasteurella multocida subsp. multocida str. Pm70
NCBI Gene ID 1244144
NCBI Protein GI 15602662
Locus Tag PM0797
Genbank Accession AE004439
Protein Accession NP_245734
Taxonomy ID 272843
Gene Starting Position 941245
Gene Ending Position 941946
Gene Strand (Orientation) -
Protein Name orotidine 5'-phosphate decarboxylase
Protein pI 5.13
Protein Weight 23616.42
Protein Length 233
Protein Note type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
DNA Sequence 
>gi|15601865:941245-941946 Pasteurella multocida subsp. multocida str. Pm70, complete genome
GTTATCTATTCACAGGTAAAGAAGCATTGATTGATTTGAGCACTTCTGCTGGGTTATCTGCTTGTGTAAT
TGGACGACCAATTACTAAATAGTCAGAACCTGCTTGAATTGCCCCCGCTGGTGTCATTACGCGACGCTGA
TCACCAAAATCACTGCCGATTGGGCGAATTCCCGGCGTAATCAGTTTAAAATCTTTACCACAGTTAGCGC
GTAAAATTTCCACTTCTTGCGGAGAACAAACTACGCCATCTAATCCAGCACGCTGTGTTAGATTGGCTAA
ACGGATTACTTGTTCCATCGGAGAAGCATTAATGCCAATTTGCAATAAATCTAGATCTTCCATACTGGTT
AATACCGTCACACTAATTAAAAGAGGCGCGTCTTTACCATAAGGTTCAAGAATTTTCTTCGCCTCCTCCA
TCATACGCAAACCACCGCTGGCATGTAAATCAACCATCCAAACCCCTAAATCTGCCGCAGAACGCACCGC
TCTTGCTACAGTATTTGGAATATCATGAAATTTTAAATCTAAAAACACATCAAAGTTGCGATCATGTAAT
GCTTTGACAAATTTCGTCCCTAATGTAGTAAACATTTCTTTACCGACTTTCAAACGACATAAGCTCGGAT
CAATTTGATCAACTAAACACAATGCCTCTTCTTCTTTTTCATAATCTAGTGCAACAATGATTTTACTCGT
CA
Protein Sequence 
>gi|15602662|ref|NP_245734.1| orotidine 5'-phosphate decarboxylase [Pasteurella multocida subsp. multocida str. Pm70]
MTSKIIVALDYEKEEEALCLVDQIDPSLCRLKVGKEMFTTLGTKFVKALHDRNFDVFLDLKFHDIPNTVA
RAVRSAADLGVWMVDLHASGGLRMMEEAKKILEPYGKDAPLLISVTVLTSMEDLDLLQIGINASPMEQVI
RLANLTQRAGLDGVVCSPQEVEILRANCGKDFKLITPGIRPIGSDFGDQRRVMTPAGAIQAGSDYLVIGR
PITQADNPAEVLKSINASLPVNR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pyrF mutant is attenuated in chickens (Harper et al., 2003).
References
Harper et al., 2003: Harper M, Boyce JD, Wilkie IW, Adler B. Signature-tagged mutagenesis of Pasteurella multocida identifies mutants displaying differential virulence characteristics in mice and chickens. Infection and immunity. 2003; 71(9); 5440-5446. [PubMed: 12933901].