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orf3a

Victor ID 4489
Gene Name orf3a
Sequence Strain (Species/Organism) SARS coronavirus ZJ0301
NCBI Protein GI 74275591
Other Database IDs CDD:151730
Taxonomy ID 344702
Gene Strand (Orientation) ?
Protein Name putative transmembrane protein 3a; Orf3a
Protein Length 274
Protein Note Protein of unknown function (DUF3092); pfam11289
Protein Sequence
>gi|74275591|gb|ABA02268.1| putative transmembrane protein 3a; Orf3a [SARS coronavirus ZJ0301]
MDLFMRFFTLGSITAQPVKIDNASPASTVHATATIPLQASLPFGWLVIGVAFLAVFQSATKIIALNKRWQ
LALYKGFQFICNLLLLFVTIYSHLLLVAAGMEAQFLYLYALIYFLQCINACRIIMRCWLCWKCKSKNPLL
YDANYFVCWHTHNYDYCIPYNSVTDTIVVTEGDGISTPKLKEDYQIGGYSEDRHSGVKDYVVVHGYFTEV
YYQLESTQITTDTGIENATFFIFNKLVKDPPNVQIHTIDGSSGVANPAMDPIYDEPTTTTSVPL

Molecule Role Virulence factor
Molecule Role Annotation MUTATION: or3a deficient strain of SARS-CoV is attenuated in causing death of Vero cells (Anan'eva, 1998).
References
Anan'eva, 1998: Anan'eva TV. [Role of GABA in the modulation of Na, K-pump activity in nerve cells after irradiation and experimental modification of membrane lipid component]. Radiatsionnaia biologiia, radioecologiia / Rossiiskaia akademiia nauk. 1998; 38(6); 800-805. [PubMed: 9889773].