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E

Victor ID 4486
Gene Name E
Sequence Strain (Species/Organism) Yellow fever virus
NCBI Protein GI 9558716
Other Database IDs CDD:145801
Taxonomy ID 11089
Gene Strand (Orientation) ?
Protein Name envelope protein
Protein Length 116
Protein Note Flavivirus glycoprotein, immunoglobulin-like domain; pfam02832
Protein Sequence
>gi|9558716|gb|AAB30044.2| envelope protein [Yellow fever virus]
TLKGTSYKMCTDKMSFVKNPTDTGHGTVVMQVKVPKGAPCRIPVIVADDLTAAINKGILVTVNPIASTND
DEVLIEVNPPFGDSYIIVGTGDSRLTYQWHKEGSSIGKLFTQTMKG

Molecule Role Virulence factor
Molecule Role Annotation MUTATION: E protein mutations in the 17D strain led to mortality and morbidity in mice defective in both type I and type II interferon responses (McArthur et al., 2005).
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References
McArthur et al., 2005: McArthur MA, Xiao SY, Barrett AD. Phenotypic and molecular characterization of a non-lethal, hamster-viscerotropic strain of yellow fever virus. Virus research. 2005; 110(1-2); 65-71. [PubMed: 15845256].