>gi|1890270|gb|AAB49718.1| nonstructural protein NS2A [Yellow fever virus]
VGLHFHEMNNGGDAMYMALIAAFSVRPGLLIGFGLRTLWSPRERLVLTLGAAMVEIALGGMMGGLWKYLN
AVSLCILTINAVASRKASNVILPLMALLTPVTMAEVRLATMLFCTVVIIGVLHQNSKDTSMQKTIPLVAL
TLTSYLGLTQPFLGLCAFLATRIFGRR
Molecule Role
Virulence factor
Molecule Role Annotation
MUTATION: A mutation in the cleavage site in NS2A resulted in a block in the production of infectious virus (Kümmerer and Rice, 2002).
References
Kümmerer and Rice, 2002: Kümmerer BM, Rice CM. Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles. Journal of virology. 2002; 76(10); 4773-4784. [PubMed: 11967294].