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NS2A

Victor ID 4485
Gene Name NS2A
Sequence Strain (Species/Organism) Yellow fever virus
NCBI Protein GI 1890270
Other Database IDs CDD:144553
Taxonomy ID 11089
Gene Strand (Orientation) ?
Protein Name nonstructural protein NS2A
Protein Length 167
Protein Note Flavivirus non-structural protein NS2A; pfam01005
Protein Sequence
>gi|1890270|gb|AAB49718.1| nonstructural protein NS2A [Yellow fever virus]
VGLHFHEMNNGGDAMYMALIAAFSVRPGLLIGFGLRTLWSPRERLVLTLGAAMVEIALGGMMGGLWKYLN
AVSLCILTINAVASRKASNVILPLMALLTPVTMAEVRLATMLFCTVVIIGVLHQNSKDTSMQKTIPLVAL
TLTSYLGLTQPFLGLCAFLATRIFGRR

Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A mutation in the cleavage site in NS2A resulted in a block in the production of infectious virus (Kümmerer and Rice, 2002).
References
Kümmerer and Rice, 2002: Kümmerer BM, Rice CM. Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles. Journal of virology. 2002; 76(10); 4773-4784. [PubMed: 11967294].