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LPG1

Victor ID 4480
Gene Name LPG1
Sequence Strain (Species/Organism) Leishmania major
NCBI Nucleotide GI 7239376
NCBI Protein GI 7239377
Protein Accession AAF43209.1
Taxonomy ID 5664
Gene Strand (Orientation) ?
Protein Name putative beta galactofuranosyl transferase
DNA Sequence 
>gi|7239376|gb|AF234766.1| Leishmania major putative beta galactofuranosyl transferase (LPG1) gene, complete cds
GGATCCGTCTGTATCGAGCGCAGCGCGTCGCGGAGCGGCGGTGTAGCTGTTCTGTTGCTCTTGCGCCATC
AACGGCGCCTCCGCTACCGCCTCACCTCGACTCGTCGATTCTTGGCCGCCTCCTCACCTCGAAAGAGGCC
AGTAAGCTTCAGCGGTACTTGACTGGCTACGGCGCAGCGATGAGGGCAAAGGCTCAGCAACGCCGACAAG
CCGAGACGCAGGCGGCATGTGCATGGAGCTGCAGGGAGTGCCACCCCGCTCGCACTTTCGAGACGGAGGA
TGATCTGCGACAGCACCAGATCGCGAAGCACTGTGGCGCGACTCCACTCGCGCCCACGCTATACGCGCGT
GTGCATGAGCAGGTCGAGACTGCGAGTCGTCGCCTGGAGGAAGCTCTGGCTGGCTTGGATATAGAGGACG
GCGGCGATAACAACTACTGCGAGGTGTGCGGGTTGCGTTTCAAGAGCGGCGATGCGTACGAAGAGCACCT
CCGCTACTTATCTCCCCTTCCAGGCGACGATGCAGCGGACTTGGTGTGCCACGTCTGCCAGCCGGCGAAG
TGTTTTACCGACCGCCGCGCACTTGAGCAGCATCGAGCCACGAAGCACGCGCCAGCATTCTCAGCGACCC
GCGAGGAAACAACTCCCGCTAACATTTAGCACCCGTGAGGTGAAGAGCACCAACGAAGAACAAAACAGAA
GACGGCAGTGCGTACACGCCCCAACGCACAGGGCTGAAGCGTCGGAAGGGGCAGCGCAGAAAGACGTCGG
GCCAGTGTCTGTTTGCTCTTCACCGGGACGTCACGCACGCAGCGTCGCGGTCCTGCCTCTCTCTCCCCCA
CCGGCACGACTCTACGAATCGAGCGGCTGTATGTCTACATGTTGCCAAGTGTTGTACCCTTGCCATTTCT
GTCTCGCTTCTCCTGCCTGCGCGTGCGTAAGGAACGACAAAAGGTAAACGTTAACAGGGCTGTGGTGCAG
CAGGGAGACCGCCGACGTACGATGACCACATACCGCCGCATGACGCTATGCGACACGCTGCAGTTTAATT
TTGTAAATTTGGATCAGCTCACAGAAACGTACAATACGTCCTTCTATGGCGAGTATGTGACGCACTGGCC
GGAGTACCAGCGCGTGTGCGTACACCCCACCACCGGTATTCCCATGGCCTACACGCTCGGCAAAGCGGAA
GGACAGGGAGAGGACTATCACGGACACGTCTCCGCCGTGTCTGTGGCACCAACGTTTCGGCGCGTCGCCC
TCGGCGAGACTCTCATGGTTGAGCTGGCGCAGATGAGCGAGCTCGTGCACAATGCCTACTTTGTGGACCT
CTTCGTCCGCAAAAGTAACCAGGTGGCACAGGACATGTACCATCGGCTGGGCTACATTGTCTACCGGACA
GTGCTCAACTATTACCACGGCGACGGCCCGAAAGGCCCGTTCAAGAGTGACGAAGACGCACTGGACATGC
GGCTTGCCCTGCGGCGGGACAAGGAGCGGCGAAAAAGTAGCGTCATTCCGCTAGACCGACCCATCAAACC
CGAAGAACTGGAGTGGGTGTGAGTACCCAGGCATTCCACACACTGCACAACGCCCCGCCGTTTCTGTCAT
GCACGAAACAAGAATAAAAAGACCGATAAACTACATCACGCACCATCACACGCGTGTGCGTCTCCCTGGG
TGAAGACGTGCATAGCCCGCCGCGAGAGCCGCCCTTATGCGTCATTCACCGTGTGTAGGACGCACAAGAG
AAATGGCCTGGCGCCTCGTGCCAGACCGCGGCTTCCGTACACACTATGCTTGCTTCTGCCTCTCTCTCTT
TCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGATGTGTGGATGTCGCCGTCCCGTTTCT
TCTCTGGTTTGGGGTGGGTGATAGCGGCAGATGCTGCCTCGACCTTGTGCACCGCACGGGTGCCGCGGGC
GACACCGCGGAAGGCAACACAGAACACACCCTTTGTCGTTCCTTTTTGCTGTCACGCAGCTGTTCCGCGT
CTACTTCCTTCTTCCGTCCGTTCTTCCTACCGCACACGGCACCTCTCCTTGCAATGCAGTCACACACTAC
CACTCAACGTTCCGTGCAGCACTTGAGCGAGTCGATCGCGCAGCCCGAGAACGCGCATAGTGTATCCTTT
TCTAGCCAAACCAGTGCCGCTTAGTCGAACCAGAGAGCACCTGGCGGAGAAATGGCGCCTCGTCGCTGGC
ATCACAACTGCCGGCGCATGGCGTCATTTGTGCGTATTGGTCTTTACACACTTCTCTTCCTCATGGGCTA
CATTGTCCCGCTTATCATTTTCTATAATCGCTCGGGCACAGAGACCTTCGAAGATACCCCTCGTCCAGGT
GAGAGGTTTATCAGTGACGAGAATTTTTTCCACTGCATCGCGGAGCGTCTCTCATATAAGGACCAACACC
CAGCACGAATCCCGTACGTGCTAATACCGGTGACGATGGATTACCAGGACATCAAGCAACTCTTCTGCAA
TATTACAGTCCCCATGACGTACATCATGTTTATTAACAATGGCATGTTCCGCCCACTGCGCTCGCTTCTC
GACCGTCTCGCCGTGGAGCTGAGGGACTACGTCGACCAGAATCTCTTTATCATTCACCACCCAGAGAACA
TCGGCTACGCGTCTGCCGTGAACGAGGGTTTGCGGCACGCTCTCAACTTCTCCGTTGCCCAGGTGCCGTG
GATCTTCATCACCAATGCCGACGTGCGCTTTGCGCCGGGGCTCATGGACGAGTTTGTCTCGCAGGCACAC
ATAAGGACACAAGGCCAGCTCGAGCGCATTCGCCGCCTCGACGAAGAGATCGTTGCCGAAATCAAGACGC
TGAAAAACGTGCCAGACCCGCGGTTTGCTTTCCGCAGCAGCCGGCACCCCATCGTCACGGCATCCTCGCT
GCCGTATCGTATTCGGACCATGCCCCCAGAGCAGATGAAGAAGCAGTTCGCCGACGCATACGGCATCTTT
TTCACAGACCACAAGGAGTTCATGGCTACATTTGCGCTGTCCCGCCTCGCCATTGCGACCTTAGGGTTCT
TCGACGAGAACTTCTACCCCGCCTACGGCGAAGATCACGACTACATGTGGCGCATGAATGCTCTGGGCTA
CCGAAAGTACTTCTCCGAGCGGGGAAAGTATGTGCACTTTCAAAACGCGAACCTCAACGTCGGTGGGTCG
GCCAAGAACCGGGGCGTCTTCAAGGACACTGCCTACTTCGTCCAGAACGTCAAGTTTTGGCGTATGAACA
ATGAGCTGTTTCGCCTGCAATATCGCCATGCGAAGTGGTTCCCTGATGATGTCACCATCTATCGAGGTGT
CAGACGCCGGCCACTACCGTTTAACGGAACCATTCCTGTCGACATGTGGGTACTCGACGCTGAAAGGCAA
AGGTCCATCTGGCAAATCGGCGAAAGCATGCGCTGTCACCGCGACTACAAGCCATACAGCACAAAGCTAC
TGGACTTTGCTGTTGATCCTAGCTAAGGGTTCTGGTCGGGAGTAATGCACGGCACACGCTCTCGCTGGCC
ATTGCGACGCGCGCATTCCTGCAGCTGCACACACTTGTACTGGTACCGGTCTGCGCCAGTCTGATCGACA
ATAATGCGCTCGCTCTGTAGCAGCGGCGCGCGGAAGGTCCTTCGCAGAGGTGTACGAAAAGCCTCTCTCC
TTGCGGCAGCTGTCGCCTACCGGAACAGGCACGAGCCATCACCGAATCAAAAAGCAGCGCATCGGACAGT
GATGAACGGTCGACGGCTGCCTTTCGGTTTCTTGGTTTTCTTGCTTTTTTTGAGGTCTTCCCCCCCCTCT
TCCTGCCTAACTTGCACTACGGCGCCACCGTGTTGCGCAAGAGTGCAAGCGCCCTTTGCGGGATGGTCCT
TGGGCAGCTTCACGCGAGCGCAGCCGCACTCATCCTTCATACACCGCACATCTGTGGAAGAGCGGCCACA
CACTCGAAGGGGCCGACGCACAGTCCCTCGCCTAGGTAGTGCTGCTGCGCCCCACATGCCTTTGTTTTTT
CTCCGCGGTCCCCCGAGGGAGGGTACCCGGAGGATGTGGTGCAGGACGTGTGCACGCCGGATCGCATTGT
CGTCACAGCGTCTCGGCGGCTTGCGCATGGGCATGCGGGCAGGAACCCCATCGGGGATCC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpg1 mutant are attenuated in mice and in macrophages (Späth et al., 2000).
References
Späth et al., 2000: Späth GF, Epstein L, Leader B, Singer SM, Avila HA, Turco SJ, Beverley SM. Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major. Proceedings of the National Academy of Sciences of the United States of America. 2000; 97(16); 9258-9263. [PubMed: 10908670].