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MyoA

Victor ID 4474
Gene Name MyoA
Sequence Strain (Species/Organism) Toxoplasma gondii
NCBI Protein GI 50400802
Other Database IDs CDD:173315
CDD:30084
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name Myosin-A
Protein Length 831
Protein Note MyoA; TgM-A
Protein Sequence 
>gi|50400802|sp|O00934.1|MYOA_TOXGO RecName: Full=Myosin-A; Short=MyoA; AltName: Full=TgM-A
MASKTTSEELKTATALKKRSSDVHAVDHSGNVYKGFQIWTDLAPSVKEEPDLMFAKCIVQAGTDKGNLTC
VQIDPPGFDEPFEVPQANAWNVNSLIDPMTYGDIGMLPHTNIPCVLDFLKVRFMKNQIYTTADPLVVAIN
PFRDLGNTTLDWIVRYRDTFDLSKLAPHVFYTARRALDNLHAVNKSQTIIVSGESGAGKTEATKQIMRYF
AAAKTGSMDLRIQNAIMAANPVLEAFGNAKTIRNNNSSRFGRFMQLDVGREGGIKFGSVVAFLLEKSRVL
TQDEQERSYHIFYQMCKGADAAMKERFHILPLSEYKYINPLCLDAPGIDDVAEFHEVCESFRSMNLTEDE
VASVWSIVSGVLLLGNVEVTATKDGGIDDAAAIEGKNLEVFKKACGLLFLDAERIREELTVKVSYAGNQE
IRGRWKQEDGDMLKSSLAKAMYDKLFMWIIAVLNRSIKPPGGFKIFMGMLDIFGFEVFKNNSLEQFFINI
TNEMLQKNFVDIVFDRESKLYRDEGVSSKELIFTSNAEVIKILTAKNNSVLAALEDQCLAPGGSDEKFLS
TCKNALKGTTKFKPAKVSPNINFLISHTVGDIQYNAEGFLFKNKDVLRAEIMEIVQQSKNPVVAQLFAGI
VMEKGKMAKGQLIGSQFLSQLQSLMELINSTEPHFIRCIKPNDTKKPLDWVPSKMLIQLHALSVLEALQL
RQLGYSYRRPFKEFLFQFKFIDLSASENPNLDPKEAALRLLKSSKLPSEEYQLGKTMVFLKQTGAKELTQ
IQRECLSSWEPLVSVLEAYYAGRRHKKQLLKKTPFIIRAQAHIRRHLVDNNVSPATVQPAF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: myoA mutant has severe impairment in host cell invasion and parasite spreading in cultured cells (Meissner et al., 2002).
References
Meissner et al., 2002: Meissner M, Schlüter D, Soldati D. Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion. Science (New York, N.Y.). 2002; 298(5594); 837-840. [PubMed: 12399593].