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M2AP

Victor ID 4473
Gene Name M2AP
Sequence Strain (Species/Organism) Toxoplasma gondii ME49
NCBI Gene ID 7900755
NCBI Protein GI 237843035
Locus Tag TGME49_014940
Genbank Accession DS984747
Protein Accession XP_002370815
Taxonomy ID 508771
Gene Starting Position 591583
Gene Ending Position 595107
Gene Strand (Orientation) +
Protein pI 4.03
Protein Weight 31575.61
Protein Length 330
DNA Sequence 
>gi|212659409:591583-595107 Toxoplasma gondii ME49 scf_1112359874706, whole genome shotgun sequence
CGACAGAGCCTCGGTGCGTCGCTTATCTCGTCAACTCGTCGCATTCCATTTCACCCGCTATCGACGCTTT
TCTGGTGCGCGTGTATACGCCAGTACACGGTTGTCCAAGTGTGAGCACACCGTCGGTTAAGAGACGCAAT
TCCAGTCCATGGATTTGTGACGCAGCTGGGTAAAGCTCGTCACATTGAAGACAGTTTTAGTACTTCCGAA
ATTTGGTTTCGCGCCCTCCCTCTAGTCTCGAGACCTGGTGGGTGGATTGTTTTTTTTTTACGCACAACTC
ACGTCACTCTCCCAACATGAAACTCGCTGCCGTGTCCAGTGCTGCCTTCGCGGCTGCTTTTTTTCCAGCA
GTTGTCAATGCAAGGAAAGGTACGTCCGCGTTTCTTTCGTAGACTTGGGCGTTCCGTCAGTAACGGAATC
CATAGTATTCATGATTTTCGAGATTGGCGCCAGACGTTCTGGGCGGGCGGTATGGAAGGAACTGCTGGCG
TCGTGGATGGGTGCGTCTCAAGACAAGCGGGGACGTTGGAGCGCCTAAGGGTAAATCCGTAAACCATATA
TAGATCTTCATCGGGAATACGCTTTTGTTCCGTGCTTGTTGTGTGTCTGTGTGTTTGCAGTTGGAAATCC
GGCGGCGCAGCCCAGTGTCCTTGTCAACGAACCGGTGGCCCTAGCTCAGCTCAGCACATGTGAGTCGAGG
TTGAGCCTCGTTGGCGAAAACCGGAATTTGGGGGATGCATTTTAGATTAGTGTGGGCCGACTATCGCAGC
TTTCGCTCGCTTCTTCTTTTACCCTGACTGTGTCAGGTGTTGGACAAAATGAACACCAAATTTTTTGTAG
AGTTTGTATGTGCGATCCTACGTCATCCTCTGAGCAGATCGCGCGATGGATGACGCGGTGGTTAGTATGG
CAGACCGTTTTAAAAGCGTGATACCGTCTGGTGCGCCTGAAGCGTCTTGTTGGCTGTGTGTTGAAGACTG
CTGCTTGAGCCGTGACAACAGATTACTTTGCAAGGACGCCAGAGTGCTTTTCTCGTTAGCACTGTTCTGT
GTATCACGAGACTCATGGGAAGCAATGATGCCCCGAGTGTCCCTGATCCCGCCCAGGAGGTGGGTTCTTA
CATCCTGTGTACAGTACTGTGACGTAAAGACTCGCGGTTTCTTCAATTATATGCATACGAAGGGCGTGTC
AGTTGGCATGCATAACGATTCGGATAATGGCTGGATTGTACAATTAGGAAAGTCTAACCGATGTCGTAAC
TGTGTTATGTTTCTGCAGTCCTCGAGCTCGTCGAGGTGCCATGTAACTCTGTTCATGTTCAGGGGGTGAT
GACCCCGAATCAAATGGTCAAAGTGACTGGTGCAGGATGGGATAATGGCGTTCTCGAGTTCTATGTCACG
AGGCCAACGAAGACAGGCGGGGACACAAGCCGAAGCCATCTTGCGTCGATCATGTGTTATTCCAAGGACA
TTGACGGCGTGCCGTCAGACAAAGCGGGAAAGTGCTTTCTGAAGAACTTTTCTGGTGAAGACTCGTCGGA
AATAGACGAAAAAGAAGTATCTCTGCCCATCAAGAGCCACAACGATGCGTTCATGTTCGTTTGTTCTTCA
AATGATGGATCCGCACTCCAGTGTGATGTTTTCGCCCTTGATAACACGTAGGTCGAATTCACACAGATTG
AGGACAACGAGAACTAACACGTTATCACGGTTGAAATAGAATAGTGGATGACCGATACTACGCATGCGCT
GTGTTTAGCAAAATGACTGGTGCCTTGAGAATTTTTTGTCACGGGCACCAGCGAATCAGAGTCCCATTTT
GATCAGCGTCGTAGATAGTTGAACATCGCTGGAATTGAATGAGTAGGTACACTGACTACAGGGAAGAAGT
CTGCTTGTAATCGAGGGTGCGGGATAGTAATCGAGGGTGGGGGATAGAAAGCCCGAAGTGTTTCTTACAA
GATCCACTGTATCTCCGCGACCAATTTTGTCTTTTGTGCTGGTGTTTCAGCAACTCTAGCGACGGGTGGA
AAGTGAATACCGTGGATCTTGGCGTCAGCGTTAGTCCGGATTTGGCATTCGGACTCACTGCAGATGGGGT
CAAGGTGAAGAAGTTGTACGCAAGCAGCGGCCTGACAGCGATCAACGACGATCCTTCCTTGGGGTGCAAG
GCTCCTCCCCATTCTCCGCCGGCCGGAGAGGAACCGAGTTTGCCGTCGCCTGAAAACAGCGGGTCTGCAA
CACCAGCGGAAGAAAGTCCGTCTGAGTCTGAATCTGTCCCGTCTTTGCCTTTGTCTCAAATTCCCTCAGA
AGTGCCCCTGTCCCAAGAGTCGCCAGTACCGCCTCAGGATGGTGAGAACCCAGATTCGCCACAAAATGAA
GACAATTCGATGCAGGAAGTCGAGAATAGCGCTTCGCAGTCGGATATCGAGGCTCAGCGGCAGGCCGAGA
ACGGCCGTCTGCCGAGTGACGATGAGGCGTAAAGATTCACGACGCACCTGTTTTTGGATATACAGTGTAA
AGAGCCAGGGCAACAGACAACACTATTTTGTGGTATATGTCGCATCTGTCGCGCGGACTGGAGTTTCGTG
CATGTCCAGGTTAGTCGGGAACGGTCGAGCGTGAACTCAGTTTTCCCGGTTCGTGAGAACAGGGGCCGGA
AGTTTGGTAGTCCCAGCCATTAGAGGGATGGAGTGTTTTTGTCTGAAAGTAACAAGTGCGTTCGGCGTCC
GGCCCCAGGCCATCGGCACGCCTGTAGAGGTGGATTTATTACCGGAGGCACCGGTCTTGTATTCTGTAGG
ATGAACTCTGCAGGAGAGTAGTGACGTGTTACGTGGAGGGTTTGAGCGAAGTACGCTCGTGATACGTCGG
CTGCAGTGCACCTGACTATCGACAAAAGCGGAAACTCACGGCCGAAATGTGTGACGCAACGCAGTCCTTG
ATATTTCAAAAATATGTTGCAATTTTGGAGTTGAAATGTTTGGATCTGTTTCCTGCCGACGTGTACCAAG
TATCAACTTCTCAGGTAATCAGCGATGGCTGGAAAATTCAGGCTGCAGGAAGCTGTCTCTACAGGGGGGA
TGGGTAGAGCGGAGACTTGAGCAGTCATCATTCAGAAAGACGCCACCATGCACATCAGCTATTCTCACTG
TGGAGCACCAGACGGCGGTAACTCCTGTCAAGCGGGAATATTCAACCCTAAATGTTTTTTCACTTAAGGC
ACGCAGCTGTTCTGGCACGCCGGTAGAAACGTAAATGCCCGGCTTCGCACGTACTATCGTCAGTTTACGT
GTATTGTGGTTCCACCGGTAGCAGTAGTGTAGTGGTATGCGGCAGTCGGAGTTTTCAGCTGTGTTCTCCA
CCGTAAGGCAGTGGACGAATTAATTCGTGCGCTGCAGCACCATGTGTGTACATCTAGCTAAAGTCCCACC
CGTCCGGAAGAAACCTGCGGTATTTCAGAGATTCGTCGCATCGTGTTACAAACTCCCCTTCTGAACTAGT
TTGGAGGGTGCGAATTGTGCTACGA
Protein Sequence 
>gi|237843035|ref|XP_002370815.1| MIC2-associated protein M2AP [Toxoplasma gondii ME49]
MKLAAVSSAAFAAAFFPAVVNARKVGNPAAQPSVLVNEPVALAQLSTFLELVEVPCNSVHVQGVMTPNQM
VKVTGAGWDNGVLEFYVTRPTKTGGDTSRSHLASIMCYSKDIDGVPSDKAGKCFLKNFSGEDSSEIDEKE
VSLPIKSHNDAFMFVCSSNDGSALQCDVFALDNTNSSDGWKVNTVDLGVSVSPDLAFGLTADGVKVKKLY
ASSGLTAINDDPSLGCKAPPHSPPAGEEPSLPSPENSGSATPAEESPSESESVPSLPLSQIPSEVPLSQE
SPVPPQDGENPDSPQNEDNSMQEVENSASQSDIEAQRQAENGRLPSDDEA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: M2AP mutant is attenuated for cell invasion and virulence in mice (Huynh et al., 2006).
References
Huynh et al., 2006: Huynh MH, Harper JM, Carruthers VB. Preparing for an invasion: charting the pathway of adhesion proteins to Toxoplasma micronemes. Parasitology research. 2006; 98(5); 389-395. [PubMed: 16385407].