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SAP1 |
| Victor ID |
4465 |
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Gene Name |
SAP1 |
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Sequence Strain (Species/Organism) |
Plasmodium yoelii yoelii str. 17XNL |
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NCBI Gene ID |
3926325
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Taxonomy ID |
352914
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Gene Strand (Orientation) |
? |
|
Protein Name |
Record to support submission of GeneRIFs for a gene not in Entrez Gene. |
|
Protein Note |
Also known as NEWENTRY |
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Molecule Role |
Virulence factor |
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Molecule Role Annotation |
MUTATION: Targeted deletion of SAP1 in the rodent malaria parasite Plasmodium yoelii generated mutant parasites that traverse and invade hepatocytes normally but cannot initiate liver-stage development in vitro and in vivo (Aly et al., 2008). |
| References |
Aly et al., 2008: Aly AS, Mikolajczak SA, Rivera HS, Camargo N, Jacobs-Lorena V, Labaied M, Coppens I, Kappe SH. Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Molecular microbiology. 2008; 69(1); 152-163. [PubMed: 18466298].
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