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FTL_0112

Victor ID 446
Gene Name FTL_0112
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951722
NCBI Protein GI 89255549
Locus Tag FTL_0112
Protein Accession YP_512910.1
Taxonomy ID 119857
Gene Starting Position 103419
Gene Ending Position 104939
Gene Strand (Orientation) +
Protein Name intracellular growth locus, subunit B
DNA Sequence 
>gi|89255449:103419-104939 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGACAATAAATAAATTAAGTCTCACTGATGAACTTTTAAATAATTTTGGGGGATCTACAGAAGTTGAT
AGTGTACTCAAAAATATAGATTTTGATGTTTCAGATGATGCTTCTAAAGTTTTATCTTTATCTACTGACT
ACAATGCTAGAAACCTTATGGCGCTATCTTTGGTATTAGCAAATAATGATAATATAAATAATTATAATCA
AAAATATATCCAGAAAGTTATTACAGTTATTGATAGGCTTATTGATTTACAAGTTAATTCTATTATATCT
AATGATGAGTTTAGAGCACTTGAGCAAGAATGGCTAAAGGTGCAAGAGGTTTGTCAAGAAGACTATGATA
ATGTTGAAGTAAGTATATTAGATGTAAAAAAAGAAGAGCTACAATATGATTTCGAGAGAAATTTATATGA
TATATCTAGTAGTGACTTTTTCAAAAAAGTTTACGTTTCAGAATTTGATCAATATGGTGGAGAACCTTAT
GGCGCAATATTAGGATTGTATAATTTTGAAAATACCACAAATGATATAATTTGGTTGACTGGAATGGGTA
TGGTGGCAAAGAATTCTCATGCACCATTTATTGCATCAATTGATAAGTCATTCTTTGGTGTTAAGGATTT
ATCAGAAATCACTCATATAAAAAGTTTTGAAGCTTTGCTTGAGCATCCTAGATATAAAGAGTGGAATGAT
TTTAGAAACCTTGATGTTGCTGCATATATAGGTTTGACCGTAGGTGATTTTATGTTGCGGCAACCATATA
ATCCTGAGAATAATCCAGTTCAGTATAAACTTATGGAAGGCTTTAATGAGTTTGTTGATTATGATAAGAA
TGAAAGTTATCTATGGGGACCTGCTTCAATTCATCTAGTTAAGAATATGATGAGATCTTATGATAAAACT
AGATGGTTCCAATATATAAGAGGAGTTGAGAGTGGTGGTTATGTAAAGAACTTGGTAGCTTGCGTATATG
ATAATAAAGGCATTCTAGAAACTAAGTCACCTTTAAATGTATTATTTGCTGATTATATGGAGTTATCACT
TGCAAATATTGGTTTAATACCATTTGTAAGTGAAAAAGGTACTAGTAATGCTTGTTTTTTTAGTGTAAAT
TCTGCTAAAAAAGTCGAAGAATTTGTAGATGGATTTGACTCAGCAAACTCAAGATTAATTGCTAACCTTT
CTTACACTATGTGTATATCGAGAATATCTCATTATATTAAATGTGTAATTAGAGATAAGATTGGTAGTAT
TGTGGATGTCGAGTCGATTCAAAAAATTCTTTCTGATTGGATATCAGAATTTGTCACCACAGTCTATCAA
CCAACCCCTTTAGAAATGGCGAGATATCCTTTCAGAAACGTTTCTATCGAGGTTAAAACCATACCGGGTA
AGCCTGGCTGGTATTCATGCAAAATAAATGTAATTCCCCACATTCAATTTGAAGGAATGAATACTACAAT
GACTATAGATACTAGGCTTGAACCAGAATTATTCGGTACAAATAATAACTA
Protein Sequence 
>gi|89255549|ref|YP_512910.1| intracellular growth locus, subunit B [Francisella tularensis subsp. holarctica LVS] MTINKLSLTDELLNNFGGSTEVDSVLKNIDFDVSDDASKVLSLSTDYNARNLMALSLVLANNDNINNYNQKYIQKVITVIDRLIDLQVNSIISNDEFRALEQEWLKVQEVCQEDYDNVEVSILDVKKEELQYDFERNLYDISSSDFFKKVYVSEFDQYGGEPYGAILGLYNFENTTNDIIWLTGMGMVAKNSHAPFIASIDKSFFGVKDLSEITHIKSFEALLEHPRYKEWNDFRNLDVAAYIGLTVGDFMLRQPYNPENNPVQYKLMEGFNEFVDYDKNESYLWGPASIHLVKNMMRSYDKTRWFQYIRGVESGGYVKNLVACVYDNKGILETKSPLNVLFADYMELSLANIGLIPFVSEKGTSNACFFSVNSAKKVEEFVDGFDSANSRLIANLSYTMCISRISHYIKCVIRDKIGSIVDVESIQKILSDWISEFVTTVYQPTPLEMARYPFRNVSIEVKTIPGKPGWYSCKINVIPHIQFEGMNTTMTIDTRLEPELFGTNNN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0112 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG3517S, under S: Function unknown
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].