Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

cylE

Victor ID 4383
Gene Name cylE
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
NCBI Gene ID 3686789
NCBI Protein GI 76788430
Locus Tag SAK_0797
Protein Accession YP_329421.1
Other Database IDs UniProtKB-ID: Q3K232_STRA1
UniRef100: UniRef100_Q3D241
UniRef90: UniRef90_Q3DB69
UniRef50: UniRef50_Q9RPK7
UniParc: UPI0000053647
EMBL: CP000114
EMBL-CDS: ABA46071.1
RefSeq_NT: NC_007432.1
EnsemblGenome: EBSTRG00000005179.
EnsemblGenome_TRS: EBSTRT00000005179
EnsemblGenome_PRO: EBSTRP00000004952
GenomeReviews: CP000114_GR
KEGG: sak:SAK_0797
TIGR: SAK_0797
HOGENOM: HBG215346
OMA: FQMEIAK
ProtClustDB: CLSK296939
BioCyc: SAGA205921:SAK_0797-MONOMER
Taxonomy ID 205921
Gene Starting Position 732244
Gene Ending Position 734247
Gene Strand (Orientation) +
Protein Name CylE protein
DNA Sequence 
>gi|76786714:732244-734247 Streptococcus agalactiae A909, complete genome
AATGAAAGATGATAATAAATTAAAGATTTCTGAAGCTTCCTTAGAAGATTATTCTGAAGTGGTTCATTTA
TTTAATAGGAATCATGTTTATCAATTTCCAGACGGTAGGCCTTTAACTGTTGATGACCTTGATTTAACGT
TAAAAGTTAAAGAAGTGACACATTTATTTTTACTGAAAAATCATGGTGTTTTGATTGGAACATCAGCTTT
CTTTAAATTTATTACCTATGGTTGTTTAGATTGGAATAGTAGCTTTAGTGGTTTTCTTTTAATTGATTCG
AAAAGTCGTAGTGGACAGGCAATCACTTATCTATATAAAACTATCTTAAAGAAGATAACAAAACTGAAGT
TTTCTAATATCTATACCGAAATCAGTAACTACAATAAACCCTCCTTAGCTTTATCAAAATTGAATGGCTT
CAAAGAGTATGATAAGACATATGAAGACATACTGCATTGTCGATCATTGCGTAGTCACCTCCCTAAGATA
TTGAATACGTTTCGTATTTCGAATTATTATGGTAAAACATACGACATATCAACTTTTCAAATTATGGAGG
AAATTGAAAATCCCTTGGAAGAGGAGACAGAAATTAGGACCAAAGTCTCTGATGAAGAAATATTATTTAA
AGCAGAAGATAGTGCTTCACTTCCTTATTATTTAAAAATGAGCTTGTTTCAAATGGAAATTGCTAGGTTA
GATAACCGTTATGTTTTACAAGTTGACTTTTTATCGGAACAAGTAAAGAGGGTTCGGGTTAAAACTGGAA
AATATCACTTGGCAAACTTAACGAGGGCTCACCCTAGCCTAACTTTAAGTCGTTTTGCCAATTATTATTA
CATTCAAGCAACTGTGGAAACCCTTTATGGTAATATCGATGTTCAACTGGAACGTCGAAAAAAGCATTAT
AGAGATGCAACTATTTGTCTTAAGAGAACTTTTCAAGGTTATGATTTACTTATCTCTCCAAATGGCAGCC
TTATTTTTGAAAAGCAGAAAAGAAAGATACTTGAAGATAGTTTTTTGATTTTTAGCCAACCTTTGGACAA
GAAATTAGTTGTAAAAGAAGAAGAAAATCACATTACAATCAAATGTTTCTATCAAGGTGCTTTAATTGAG
AAAATCATGACATTTACAAGTGACGAAGAAATCACTTGTGTTTATAAATGTAATCAAAAGGCTAAAGAGA
TGTTCCCAAAATTATTGAAACAGACTTTCAAGTTACACTGCCAAGAGCAGTTGATTAGAGATAGTGAAGG
TTATCTTGTGAATGTTCCAGGAAGTTACCCGATTGAGCATGATGATTTTCTTCGAGCAGATAAGTTTGAA
GATAGACAATTCCATTATTACCTCCCGAATGAAGATAAAATGATTTCCTATTCTCCTCCTGGCAAAGCCA
GCAATCAAATGCAATTTAGACCCTTATGTCTTATTGATACAGATAGCCTTTCTTTTCCACTGACTTATCA
TTTTAGGATTTCACAAGCATCATCGGAGGAGGCGTTAATCAATCTAAAAAAACAGCCAATATGGGACAGC
AACTACCAAGCGTCAGCAACTGACCTTTTAAAACATATCTCTAACCTAACATTAGAAGAAGAGAAGGATT
ATGGCATCAAGAGAATGATAGCTAACAGAAAGCATTATCCTAGTCACAAACTGGTTTTAGCCTATAATCA
GATTGTTTTGCCTAAGAATGAAATTCCAAGAGACAGTGAATTATATTCTATTTCTTTTGATTATCGAATT
AGAGGAAAGTTTGTCCAAATCCGCCAAGGGGAACATGTCAAATATGATAATAAATCCTATGTTTTGGAAA
ATAGTCAACAATTAGTATTGTATGTAGCTAGCGATGATAAATATATACTAATTTCTGCTAAAAATGGAAT
ATTTTATTCTTACAAAGAGAACAATCATTTAAAAATAAGGTGCATGTTTAAAAGGAACTCACCTTATGCT
ACAAATGTGAGCATTACAGAATATAGAAAGTGTGAAGAAAAATG
Protein Sequence 
>gi|76788430|ref|YP_329421.1| CylE protein [Streptococcus agalactiae A909] MKDDNKLKISEASLEDYSEVVHLFNRNHVYQFPDGRPLTVDDLDLTLKVKEVTHLFLLKNHGVLIGTSAFFKFITYGCLDWNSSFSGFLLIDSKSRSGQAITYLYKTILKKITKLKFSNIYTEISNYNKPSLALSKLNGFKEYDKTYEDILHCRSLRSHLPKILNTFRISNYYGKTYDISTFQIMEEIENPLEEETEIRTKVSDEEILFKAEDSASLPYYLKMSLFQMEIARLDNRYVLQVDFLSEQVKRVRVKTGKYHLANLTRAHPSLTLSRFANYYYIQATVETLYGNIDVQLERRKKHYRDATICLKRTFQGYDLLISPNGSLIFEKQKRKILEDSFLIFSQPLDKKLVVKEEENHITIKCFYQGALIEKIMTFTSDEEITCVYKCNQKAKEMFPKLLKQTFKLHCQEQLIRDSEGYLVNVPGSYPIEHDDFLRADKFEDRQFHYYLPNEDKMISYSPPGKASNQMQFRPLCLIDTDSLSFPLTYHFRISQASSEEALINLKKQPIWDSNYQASATDLLKHISNLTLEEEKDYGIKRMIANRKHYPSHKLVLAYNQIVLPKNEIPRDSELYSISFDYRIRGKFVQIRQGEHVKYDNKSYVLENSQQLVLYVASDDKYILISAKNGIFYSYKENNHLKIRCMFKRNSPYATNVSITEYRKCEEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cylE mutant has decreased invasion of lung epithelial cells (Doran et al., 2002).
References
Doran et al., 2002: Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. The Journal of infectious diseases. 2002; 185(2); 196-203. [PubMed: 11807693].