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pepN

Victor ID 4382
Gene Name pepN
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
NCBI Gene ID 3686784
NCBI Protein GI 76788425
Locus Tag SAK_1081
Protein Accession YP_329702.1
Other Database IDs UniProtKB-ID: Q3K1A1_STRA1
UniRef100: UniRef100_Q3D2L3
UniRef90: UniRef90_Q3D2L3
UniRef50: UniRef50_A2RI32
UniParc: UPI00000E2A0F
EMBL: CP000114
EMBL-CDS: ABA46066.1
RefSeq_NT: NC_007432.1
MEROPS: M01.002
EnsemblGenome: EBSTRG00000005945.
EnsemblGenome_TRS: EBSTRT00000005945
EnsemblGenome_PRO: EBSTRP00000005718
GenomeReviews: CP000114_GR
KEGG: sak:SAK_1081
TIGR: SAK_1081
HOGENOM: HBG515894
OMA: EYKAFFE
ProtClustDB: CLSK876725
BioCyc: SAGA205921:SAK_1081-MONOMER
Taxonomy ID 205921
Gene Starting Position 1052641
Gene Ending Position 1055190
Gene Strand (Orientation) -
Protein Name aminopeptidase N
DNA Sequence 
>gi|76786714:1052641-1055190 Streptococcus agalactiae A909, complete genome
ATTAGATATATTTTTTGATAGTATTGATAACTTCTTCTTTTTGCTTCGTGATTAAAAGGACACGAGCAGA
AATTTCTTTAATTCCCATTGAAATATTACGGCTAATCGCCATATCGCTTAATTGAGGCTCGAAAAAGTTT
TTATATTGTTCAAGGCGTTCTTCTGTTTTGAAACTACTTGAGGGATAAATCACAAATTTATCAAAACTCA
TATCACCACCTAGAGTTGCTTTGATCCATTCCCAGTTTTCTTGGGCCCACTCCCAGACACTTTCTTGTGT
AAAAGAATTTTTAAGGAAAGTAGCATACCAACTCATAGCTAAGTCTTGTGGTTTCACAATATCTTTATTT
TTCCAATCTGACAATAATTTCTTGAGTGTCTTGCTATCTGTAGTATGAGATAAAGCACTCGCTAGTTGTC
GTTTGAAATTCCCATCGGTAGTAGTACTATAAGTCTCTAATAACAAGTGGCTAAGTTCTTTGGATTCGAA
ATGCTTCATTTCATTGGTAAGAACTAACAGGCGAATTGCAGCTGGTATAGCAGCGATATTATTTTCGTGG
GCTTTAAAAATATGGTGAGCTTCTTCAATAGCATGTTCATTATCTGAGTAGAGAGCAAGGCTTAGGGATA
GATGACGGACCATTTCGCTATCATCTCCTTCTCCTTCTCTTTTTTCAAAGCCAAGTCTATTAAAATTAAA
TGCTGATAATTTATTAACAAATTCTTTAAAGTCGAATTCATCTTGGCTATCTTCCTGGACGAATAAGGAT
AAACCATCAATAACACTCTTAATAGCAGAGTTAACAAGATATGATGTCTCTTGGCTCAAAAGAGAGACTA
AAGGTATTAAACTACTATATGAAATCATACCACTTTCAGCAAGTAAATGACGTTCTTGTACAATTTGTAG
TTTAGAAATGTTATCCATAAGAGGAAGATCAGAAATGATATGCTCTAAGAGTTGACCTTGATAGTTAGTA
ATGTAATGTGCAGTATTTTCAGTATTGAAACGCAGTGCACCATTTTCTTTGTTCTTTTCAGCTAACTGAC
TAAAATTGGGGATTACTACCGTTTCCTCGGTTAATATCTCTGGGATTCCTTCCCAATTACTATTAAGAGG
AATTTGCCACAAGCGAGACTTATCTTCGTGTTCACCAATAAAGAATTGTTTTTGAGTTAAAATGAGCTCA
TCTTCTTCTATTTTGGCTGCCATCACAGGGTATCCTGGTTGCTCTAACCAAGAATCCATGAAAGCTGCAA
CATCTTTTCCTGAGGTTTGAGAAAGTGCATTCCAAAGGTCACGACCAATAGTATTTTGATATTGATGTTT
TTCAAAATAAATTTTTAGTCCTGCGGCAAAATCTGTATCGCCTAACCAGCGACGTAACATGTGCATGAGG
CGGCTACCTTTTGCATAAACGATAGCTGGATCAAAAAGTGTGTTAATTTCATCAGGATGATTGACCTCAA
CGTGAACAGATTGGACGCCATCTGTGGCATCACGCTTAAGAGCTAATGGTAGACCACCTGTTTGAAAGTC
TTCAAATATATTAAGTTTTGGTTCAATATAATCAATTGATACATATTCCATCATATTAGCAAATGATTCA
TTTAACCATAAATCATCCCACCATTTCATAGTAACGAGGTTACCAAACCACTGGTGAGCTATTTCATGTG
CTACAACTAATGCTACTTGCTGACGGCTGGAAACACTAGAGTTCTCATCTACTAAAAGATAGACTTCACG
ATATGTTACTAATCCCCAATTTTCCATAGCTCCAGCAGAAAAATCAGGTAGAGCAACATGGAGTGACTGA
GGAATAGGATAACGTACACCAAAGTAGTCCTCATAAAACTCAATAACACGCACAACGATATCTAAAGAAA
AATCTAATTCATTTAACTGATGGGCTTTTGTGGCATATGAGCCAACAAGAGTGCCGTTTTTGGTATGTGT
TGTTTTACCATGCAATTCCCCCAAGGCAAAAGCTAATAAATATGAGGACATTTTAGGTGTGGTGTCAAAT
GTCCATAAACCTGTTTCTTGACGTTGTTCAGCATTGATTTCCGGCATATTTGAAAGAGCAATCTCTCCTT
CTTTTTGATCGAATTTTAGGCTCAAATCAAAGGTTGCTTTTGCTTCTGGTTCGTCAATACTTGGGAATAC
TTCACGAGCAAAATGACTTTCAAATTGTGTGGAGATAACCTCTTTTTTGATGCCATTAACTGTATAGTAA
GATGGATACATACCTGTCATATTATCGGTAATGTGACCGCTGAATTCAAAGACTAATACCATGCTACCAG
TTTCATGCAATTGAATATGCATAGCTTCATTGTCTTCATCTAGTTGGAAATCTAATGGTTGATTATCTAA
TAAGACAGATTTAATGGTTAACCCTTTTTGGTGAAAAGAGATATTGTTATCTAAGGCTTCGCCAGACACA
GCAACGTTACCTGAAAAGGTTTTAGTTTGACGATTAATATCCAAGAAAAGGTTATAGTTTTCAGGGACAA
ATTTGGTAACAAAATGTTCTACAGTTTTCA
Protein Sequence 
>gi|76788425|ref|YP_329702.1| aminopeptidase N [Streptococcus agalactiae A909] MKTVEHFVTKFVPENYNLFLDINRQTKTFSGNVAVSGEALDNNISFHQKGLTIKSVLLDNQPLDFQLDEDNEAMHIQLHETGSMVLVFEFSGHITDNMTGMYPSYYTVNGIKKEVISTQFESHFAREVFPSIDEPEAKATFDLSLKFDQKEGEIALSNMPEINAEQRQETGLWTFDTTPKMSSYLLAFALGELHGKTTHTKNGTLVGSYATKAHQLNELDFSLDIVVRVIEFYEDYFGVRYPIPQSLHVALPDFSAGAMENWGLVTYREVYLLVDENSSVSSRQQVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIDYIEPKLNIFEDFQTGGLPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRWLGDTDFAAGLKIYFEKHQYQNTIGRDLWNALSQTSGKDVAAFMDSWLEQPGYPVMAAKIEEDELILTQKQFFIGEHEDKSRLWQIPLNSNWEGIPEILTEETVVIPNFSQLAEKNKENGALRFNTENTAHYITNYQGQLLEHIISDLPLMDNISKLQIVQERHLLAESGMISYSSLIPLVSLLSQETSYLVNSAIKSVIDGLSLFVQEDSQDEFDFKEFVNKLSAFNFNRLGFEKREGEGDDSEMVRHLSLSLALYSDNEHAIEEAHHIFKAHENNIAAIPAAIRLLVLTNEMKHFESKELSHLLLETYSTTTDGNFKRQLASALSHTTDSKTLKKLLSDWKNKDIVKPQDLAMSWYATFLKNSFTQESVWEWAQENWEWIKATLGGDMSFDKFVIYPSSSFKTEERLEQYKNFFEPQLSDMAISRNISMGIKEISARVLLITKQKEEVINTIKKYI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pepN mutant is attenuated in rats (Jones et al., 2000).
COG COG0308E, under E: Amino acid transport and metabolism
References
Jones et al., 2000: Jones AL, Knoll KM, Rubens CE. Identification of Streptococcus agalactiae virulence genes in the neonatal rat sepsis model using signature-tagged mutagenesis. Molecular microbiology. 2000; 37(6); 1444-1455. [PubMed: 10998175].