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FTL_1240

Victor ID 438
Gene Name FTL_1240
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951515
NCBI Protein GI 89256558
Locus Tag FTL_1240
Protein Accession YP_513920.1
Taxonomy ID 119857
Gene Starting Position 1186749
Gene Ending Position 1187861
Gene Strand (Orientation) +
Protein Name phospho-2-dehydro-3-heoxyheptonate aldolase
DNA Sequence 
>gi|89255449:1186749-1187861 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
AATGATAGGTGATAAAAACTTTGATAAAGTTTCTAATATAAATATAAAAAAGGAAAAAGTATTGATTCCT
GCAGAAGTTCTAATCCAAGATATACCTCTTTTAAAGACTTCTTTTGAAACTGTAAGAAAATCTCGTAAAG
AAATAGCTAATATCATCCATGGAAATGATGATAGAGTTGCTGTAGTTGTAGGACCTTGCTCTATTCATGA
TCCTGCTGCTGCAATTGAGTATGCTACTAAACTCAAAGAGCAAGTTAAGAAATTTCATAAAGATATACTT
ATTATAATGAGGGTATATTTTGAAAAACCACGTACTACGATTGGTTGGAAAGGATTTATCAATGACCCTG
ATTTAGATAACTCATATAATATCAACAAAGGTTTACGTCTTGCGCGTAATTTATTATCAGATTTAACTAA
TATGGGACTACCGTGTGCAACTGAATTTCTAGATGTAATTACTCCACAATACTTTGCTGAGCTAATCACT
TGGGGAGCAATTGGCGCTAGAACTGTTGAAAGTCAGGTACATAGAGAATTAGCTTCTGGTCTTTCTGCAT
CGATTGGTTTTAAAAATGCCACTAATGGTGATGTCCAAGTAGCTGTAGATGCTGTAAAATCTGCCACTTA
TCCCCATCACTTCTTAAGTACGACAAAATCTGGTTCTACAGCAATATTTGCAACTAAAGGTAACCAAAAT
GGTCATGTAATTCTTCGTGGTGGTGCCTCTGGTCCTAACTTTAGTAAAGAGCATGTTGATGACTGTATTG
CTAAACTAAAAAAAGCTGATATTAATACTAAGGTAATGATTGACTGTAGTCACGGCAATAGTCAAAAAGA
TCATTCTAAGCAAATTAGCGTATTAGCTGATATTTGTGAGCAAATAAAGCACAGTAACGATATTTTTGGG
GTAATGATAGAAAGTAATCTTGTTGCTGGTAATCAAGATATCAATAAAAAACCTCTCACTTATGGGCAAA
GTGTCACAGATAAATGCGTTGACTTTGAAGAAACAGTTAAGATGCTAGAAATGTTAGCTGAAGTAGTCCA
GGTAAGACGTGGTTCTCAAACTAAACAACAAGTTAAAGAAGAGTCACAATTTTCTTTACTGTA
Protein Sequence 
>gi|89256558|ref|YP_513920.1| phospho-2-dehydro-3-deoxyheptonate aldolase [Francisella tularensis subsp. holarctica LVS] MIGDKNFDKVSNINIKKEKVLIPAEVLIQDIPLLKTSFETVRKSRKEIANIIHGNDDRVAVVVGPCSIHDPAAAIEYATKLKEQVKKFHKDILIIMRVYFEKPRTTIGWKGFINDPDLDNSYNINKGLRLARNLLSDLTNMGLPCATEFLDVITPQYFAELITWGAIGARTVESQVHRELASGLSASIGFKNATNGDVQVAVDAVKSATYPHHFLSTTKSGSTAIFATKGNQNGHVILRGGASGPNFSKEHVDDCIAKLKKADINTKVMIDCSHGNSQKDHSKQISVLADICEQIKHSNDIFGVMIESNLVAGNQDINKKPLTYGQSVTDKCVDFEETVKMLEMLAEVVQVRRGSQTKQQVKEESQFSLL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1240 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0722E, under E: Amino acid transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].