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lmb from Streptococcus agalactiae A909

Victor ID 4375
Gene Name lmb from Streptococcus agalactiae A909
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
NCBI Gene ID 3685811
NCBI Protein GI 76787520
Locus Tag SAK_1319
Protein Accession YP_329931.1
Other Database IDs UniProtKB-ID: Q3K0M2_STRA1
UniRef100: UniRef100_B5XIS2
UniRef90: UniRef90_Q1J4I1
UniRef50: UniRef50_B4U552
UniParc: UPI000005392D
EMBL: CP000114
EMBL-CDS: ABA45161.1
RefSeq_NT: NC_007432.1
EnsemblGenome: EBSTRG00000004184.
EnsemblGenome_TRS: EBSTRT00000004184
EnsemblGenome_PRO: EBSTRP00000003957
GenomeReviews: CP000114_GR
KEGG: sak:SAK_1319
TIGR: SAK_1319
HOGENOM: HBG731008
OMA: CGASNDK
ProtClustDB: CLSK877302
BioCyc: SAGA205921:SAK_1319-MONOMER
Taxonomy ID 205921
Gene Starting Position 1297777
Gene Ending Position 1298697
Gene Strand (Orientation) -
Protein Name laminin-binding surface protein
DNA Sequence 
>gi|76786714:1297777-1298697 Streptococcus agalactiae A909, complete genome
TTTACTTCAACTGTTGATAGAGCACTTCCAAATTTGCTCTAAGATTTTCTAGATATGTCTTGTTTCCGCT
TGGAGCAGCTTCAAGTGGACTTAATGTCTTTACTTTAGCTCCTGTTGATTTCGCAATAGCATGAGCAATT
TTGGGATTGACGTTGTCTTCTGCAAAAATAGTCTTGACGTTGTATTCTTTGACAAAGTCTTGAATTTCTT
TCAATTGGCGAGGAGAGGGCTCTTGCTCTGGAGAAATACCCGAGATACCAAGTTGTTTCAAGCCGAATCG
TTTAGCCAGATAAGAAAATGCCGTGTGTTGCGTCACGAATGTTTTTGAGCGCACCTTTTTAAATTTTTGA
GTGTATTCTTCAGTTAGTTGCTCTGCTTCTTTTTTGAAAGCCTTAGCCTTTTTAGTGTAACTGTCTTTGT
GTTTAGGATCCAAACGTCCTAGCTCTTTAGCGATATTAACAGCTTCCTCACCAGCTAAAACGGGATCCGT
CCAGGTATGTGGGTCATAAAGTGTCGCAGGGTCAATGCCTTGTGTGACTTCCATATCTTCTAGCCCTTTG
ACTCTATCTAGTGTCAAAGGTTTTGACGCTTCAAACACATCAACCTTTGATTTTTTTAAATTAGGGTCTA
GATCCCTTGCCCAAGCTTCTAAGGTATGTGAATGGTAAACAAACAAATCCGCGTCATAAATAGCTGCCAC
ATCATTTACAGACGGTTCAAAGGAATGAATGCCTGCACCTGATTGGATCATCCTCACATCATTGAGGTCT
CCAGATACTTCTTTTGTCATCGCATACATTGGGTAAAAGCTGGTTACAACTGACATGCCTTGCGTAGGCT
GTTTGGGGTTTGCTGACTTATCACACCCTGCTATCATTACTAAACTCACAACCATAGCCATGAGAAAAAA
ACCTTTTTTCA
Protein Sequence 
>gi|76787520|ref|YP_329931.1| laminin-binding surface protein [Streptococcus agalactiae A909] MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lmb mutant has reduced invasion of human brain microvascular endothelial cells compared to the wildtype (Tenenbaum et al., 2007).
COG COG0803P, under P: Inorganic ion transport and metabolism
References
Tenenbaum et al., 2007: Tenenbaum T, Spellerberg B, Adam R, Vogel M, Kim KS, Schroten H. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein Lmb. Microbes and infection / Institut Pasteur. 2007; 9(6); 714-720. [PubMed: 17400016].