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SAK_0517

Victor ID 4374
Gene Name SAK_0517
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
NCBI Gene ID 3685804
NCBI Protein GI 76787513
Locus Tag SAK_0517
Protein Accession YP_329152.1
Other Database IDs UniProtKB-ID: BCA_STRA1
UniRef100: UniRef100_Q02192
UniRef90: UniRef90_Q02192
UniRef50: UniRef50_Q02192
UniParc: UPI0000034BD4
EMBL: M97256
EMBL: CP000114
EMBL-CDS: AAA26848.1
EMBL-CDS: ABA45154.1
RefSeq_NT: NC_007432.1
PDB: 1YWM
PDB: 2O0I
EnsemblGenome: EBSTRG00000005659
EnsemblGenome_TRS: EBSTRT00000005659
EnsemblGenome_PRO: EBSTRP00000005432
GenomeReviews: CP000114_GR
KEGG: sak:SAK_0517
TIGR: SAK_0517
HOGENOM: HBG219698
OMA: TPDSSTE
ProtClustDB: CLSK452417
BioCyc: SAGA205921:SAK_0517-MONOMER
Taxonomy ID 205921
Gene Starting Position 459255
Gene Ending Position 462317
Gene Strand (Orientation) +
Protein Name C protein alpha-antigen
DNA Sequence 
>gi|76786714:459255-462317 Streptococcus agalactiae A909, complete genome
TATGTTTAGAAGGTCTAAAAATAACAGTTATGATACTTCACAGACGAAACAACGGTTTTCAATTAAGAAG
TTCAAGTTTGGTGCAGCTTCTGTACTAATTGGTCTTAGTTTTTTGGGTGGGGTTACACAAGGTAATCTTA
ATATTTTTGAAGAGTCAATAGTTGCTGCATCTACAATTCCAGGGAGTGCAGCGACCTTAAATACAAGCAT
CACTAAAAATATACAAAACGGAAATGCTTACATAGATTTATATGATGTAAAATTAGGTAAAATAGATCCA
TTACAATTAATTGTTTTAGAACAAGGTTTTACAGCAAAGTATGTTTTTAGACAAGGTACTAAATACTATG
GGGATGTTTCTCAGTTGCAGAGTACAGGAAGGGCTAGTCTTACCTATAATATATTTGGTGAAGATGGACT
ACCACATGTAAAGACTGATGGACAAATTGATATAGTTAGTGTTGCTTTAACTATTTATGATTCAACAACC
TTGAGGGATAAGATTGAAGAAGTTAGAACGAATGCAAACGATCCTAAGTGGACGGAAGAAAGTCGTACTG
AGGTTTTAACAGGATTAGATACAATTAAGACAGATATTGATAATAATCCTAAGACGCAAACAGATATTGA
TAGTAAAATTGTTGAGGTTAATGAATTAGAGAAATTGTTAGTATTGTCAGTACCGGATAAAGATAAATAT
GATCCAACAGGAGGGGAAACAACAGTACCCCAAGGGACACCAGTTTCAGATAAAGAAATCACAGACTTAG
TTAAGATTCCAGATGGCTCAAAAGGGGTTCCGACAGTTGTTGGTGATCGTCCAGATACTAACGTTCCTGG
AGATCATAAAGTAACGGTAGAAGTAACGTATCCAGATGGAACAAAGGATACAGTAGAAGTAACGGTTCAT
GTGACACCAAAACCAGTACCGGATAAAGATAAATATGATCCAACAGGAGGGGAAACAACAGTACCCCAAG
GGACACCAGTTTCAGATAAAGAAATCACAGACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCGAC
AGTTGTTGGTGATCGTCCAGATACTAACGTTCCTGGAGATCATAAAGTAACGGTAGAAGTAACGTATCCA
GATGGAACAAAGGATACAGTAGAAGTAACGGTTCATGTGACACCAAAACCAGTACCGGATAAAGATAAAT
ATGATCCAACAGGAGGGGAAACAACAGTACCCCAAGGGACACCAGTTTCAGATAAAGAAATCACAGACTT
AGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCGACAGTTGTTGGTGATCGTCCAGATACTAACGTTCCT
GGAGATCATAAAGTAACGGTAGAAGTAACGTATCCAGATGGAACAAAGGATACAGTAGAAGTAACGGTTC
ATGTGACACCAAAACCAGTACCGGATAAAGATAAATATGATCCAACAGGAGGGGAAACAACAGTACCCCA
AGGGACACCAGTTTCAGATAAAGAAATCACAGACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCG
ACAGTTGTTGGTGATCGTCCAGATACTAACGTTCCTGGAGATCATAAAGTAACGGTAGAAGTAACGTATC
CAGATGGAACAAAGGATACAGTAGAAGTAACGGTTCATGTGACACCAAAACCAGTACCGGATAAAGATAA
ATATGATCCAACAGGAGGGGAAACAACAGTACCCCAAGGGACACCAGTTTCAGATAAAGAAATCACAGAC
TTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCGACAGTTGTTGGTGATCGTCCAGATACTAACGTTC
CTGGAGATCATAAAGTAACGGTAGAAGTAACGTATCCAGATGGAACAAAGGATACAGTAGAAGTAACGGT
TCATGTGACACCAAAACCAGTACCGGATAAAGATAAATATGATCCAACAGGAGGGGAAACAACAGTACCC
CAAGGGACACCAGTTTCAGATAAAGAAATCACAGACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTC
CGACAGTTGTTGGTGATCGTCCAGATACTAACGTTCCTGGAGATCATAAAGTAACGGTAGAAGTAACGTA
TCCAGATGGAACAAAGGATACAGTAGAAGTAACGGTTCATGTGACACCAAAACCAGTACCGGATAAAGAT
AAATATGATCCAACAGGAGGGGAAACAACAGTACCCCAAGGGACACCAGTTTCAGATAAAGAAATCACAG
ACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCGACAGTTGTTGGTGATCGTCCAGATACTAACGT
TCCTGGAGATCATAAAGTAACGGTAGAAGTAACGTATCCAGATGGAACAAAGGATACAGTAGAAGTAACG
GTTCATGTGACACCAAAACCAGTACCGGATAAAGATAAATATGATCCAACAGGAGGGGAAACAACAGTAC
CCCAAGGGACACCAGTTTCAGATAAAGAAATCACAGACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGT
TCCGACAGTTGTTGGTGATCGTCCAGATACTAACGTTCCTGGAGATCATAAAGTAACGGTAGAAGTAACG
TATCCAGATGGAACAAAGGATACAGTAGAAGTAACGGTTCATGTGACACCAAAACCAGTACCGGATAAAG
ATAAATATGATCCAACAGGAGGGGAAACAACAGTACCCCAAGGGACACCAGTTTCAGATAAAGAAATCAC
AGACTTAGTTAAGATTCCAGATGGCTCAAAAGGGGTTCCGACAGTTGTTGGTGATCGTCCAGATACTAAC
GTTCCTGGAGATCATAAAGTAACGGTAGAAGTAACGTATCCAGATGGAACAAAGGATACAGTAGAAGTAA
CGGTTCATGTGACACCAAAACCAGTACCGGATAAAGATAAATATGATCCAACAGGTAAAGCTCAGCAAGT
CAACGGTAAAGGAAATAAACTACCAGCAACAGGTGAGAATGCAACTCCATTCTTTAATGTTGCAGCTTTG
ACAATTATATCATCAGTTGGTTTATTATCTGTTTCTAAGAAAAAAGAGGATTA
Protein Sequence 
>gi|76787513|ref|YP_329152.1| C protein alpha-antigen [Streptococcus agalactiae A909] MFRRSKNNSYDTSQTKQRFSIKKFKFGAASVLIGLSFLGGVTQGNLNIFEESIVAASTIPGSAATLNTSITKNIQNGNAYIDLYDVKLGKIDPLQLIVLEQGFTAKYVFRQGTKYYGDVSQLQSTGRASLTYNIFGEDGLPHVKTDGQIDIVSVALTIYDSTTLRDKIEEVRTNANDPKWTEESRTEVLTGLDTIKTDIDNNPKTQTDIDSKIVEVNELEKLLVLSVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGGETTVPQGTPVSDKEITDLVKIPDGSKGVPTVVGDRPDTNVPGDHKVTVEVTYPDGTKDTVEVTVHVTPKPVPDKDKYDPTGKAQQVNGKGNKLPATGENATPFFNVAALTIISSVGLLSVSKKKED
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: C protein alpha antigen mutant is attenuated in mice (Li et al., 1997).
References
Li et al., 1997: Li J, Kasper DL, Ausubel FM, Rosner B, Michel JL. Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus. Proceedings of the National Academy of Sciences of the United States of America. 1997; 94(24); 13251-13256. [PubMed: 9371832].