Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

murF

Victor ID 4372
Gene Name murF
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
NCBI Gene ID 3685706
NCBI Protein GI 76788062
Locus Tag SAK_0893
Protein Accession YP_329515.1
Other Database IDs UniProtKB-ID: Q3K1T8_STRA1
UniRef100: UniRef100_Q3CZR5
UniRef90: UniRef90_Q3CZR5
UniRef50: UniRef50_Q1JAX8
UniParc: UPI0000053C56
EMBL: CP000114
EMBL-CDS: ABA45703.1
RefSeq_NT: NC_007432.1
EnsemblGenome: EBSTRG00000005401.
EnsemblGenome_TRS: EBSTRT00000005401
EnsemblGenome_PRO: EBSTRP00000005174
GenomeReviews: CP000114_GR
KEGG: sak:SAK_0893
TIGR: SAK_0893
HOGENOM: HBG617121
OMA: ANPASMR
ProtClustDB: CLSK876736
BioCyc: SAGA205921:SAK_0893-MONOMER
Taxonomy ID 205921
Gene Starting Position 841378
Gene Ending Position 842745
Gene Strand (Orientation) +
Protein Name UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
DNA Sequence 
>gi|76786714:841378-842745 Streptococcus agalactiae A909, complete genome
TATGAAGCTTAGTTTGCATGAAGTTGCTAAAGTAGTTGGCGCTAAAAATCAAGTATCAGAGTTTGAAGAC
GTTCCCCTGGGAAATATTGAATTTGATAGTCGTAATATCAGTGAAGGTGACTTATTTCTTCCCTTAAAAG
GAGCAAGAGATGGACATGAGTTTATAGAGATGGCTTTTGATAATGGAGCAATAGCAACCATTTCAGAGAA
GGAAATAGAGGGTCATCCTTATCTTTTAGTGTCTGATGCACTTAAAGCATTTCAAGTCTTGGCACAGTAT
TATATTGAAAAGATGAACGTTGATGTTATTGCAGTAACTGGCTCAAATGGTAAGACAACAACTAAAGATA
TGATAGCTGCAATCTTATCAACCACATATAAGACTTATAAAACACAAGGAAACTACAATAACGAGATTGG
CTTACCCTATACTGTGCTACACATGCCAGAAGATACTGAAAAAATTATTTTGGAGATGGGACAGGATCAT
CTTGGAGATATCCATGTGTTATCTGAAATTGCAAAACCACGTATTGCTGTTGTTACTTTGATTGGTGAAG
CACACTTAGAATTTTTTGGTAGTCGAGAAAAGATTGCAGAAGGGAAAATGCAAATCACAGATGGTATGAG
TTCAGATGGCATATTAATTGCACCGGGAGATCCAATTATTGATCCATATCTTCCAGCAAACCAGATGACT
ATTCGTTTTGGTCATGACCAAGAATTGCAAGTGACAGAACTCAAAGAAGAAAAACATTCCTTAACTTTTA
AAACTAATGCTTTGGAGCACCAATTACGTATACCAGTACCTGGTAAGTACAATGCAACTAATGCGATGGT
CGCTGCCTATGTTGGAAAATTATTAGCAGTAGCAGAAGAAGATATAGTGGATGCTCTAGAAAATCTTCAA
CTAACTCGTAATCGCACCGAATGGAAGAAATCAGCCAATGGAGCAGATATTTTATCAGATGTTTACAATG
CTAACCCAACGGCTATGCGATTGATACTAGAAACCTTTTCAGCTATTCCCAATAATGATGGTGGAAAGAA
GATTGCTCTTTTAGCTGATATGAAAGAACTGGGAGAACAATCTGTGGATTTACATAATCAAATGATTATG
AGTATCAGACCTGACTCTATTGATACTTTGATTTGTTATGGCCAGGATATTGAGGGGTTGGCTCAATTAG
CAAGCCAGATGTTCCCAATTGGTAAAGTGTATTTCTTTAAAAAGAATCAAGAAGTAGATCAGTTTGATCA
ATTGCTTGCAAAAGTAAAAGATACTCTTAAGGAGAAAGATCAAATATTATTAAAAGGTTCTAACTCAATG
AATCTTTCTAAAATAGTTGATATTCTTGAAGTAGGATA
Protein Sequence 
>gi|76788062|ref|YP_329515.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Streptococcus agalactiae A909] MKLSLHEVAKVVGAKNQVSEFEDVPLGNIEFDSRNISEGDLFLPLKGARDGHEFIEMAFDNGAIATISEKEIEGHPYLLVSDALKAFQVLAQYYIEKMNVDVIAVTGSNGKTTTKDMIAAILSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIILEMGQDHLGDIHVLSEIAKPRIAVVTLIGEAHLEFFGSREKIAEGKMQITDGMSSDGILIAPGDPIIDPYLPANQMTIRFGHDQELQVTELKEEKHSLTFKTNALEHQLRIPVPGKYNATNAMVAAYVGKLLAVAEEDIVDALENLQLTRNRTEWKKSANGADILSDVYNANPTAMRLILETFSAIPNNDGGKKIALLADMKELGEQSVDLHNQMIMSIRPDSIDTLICYGQDIEGLAQLASQMFPIGKVYFFKKNQEVDQFDQLLAKVKDTLKEKDQILLKGSNSMNLSKIVDILEVG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: murF mutant is attenuated in rats (Jones et al., 2000).
COG COG0770M, under M: Cell wall/membrane/envelope biogenesis
References
Jones et al., 2000: Jones AL, Knoll KM, Rubens CE. Identification of Streptococcus agalactiae virulence genes in the neonatal rat sepsis model using signature-tagged mutagenesis. Molecular microbiology. 2000; 37(6); 1444-1455. [PubMed: 10998175].