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FTL_1233

Victor ID 437
Gene Name FTL_1233
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951508
NCBI Protein GI 89256552
Locus Tag FTL_1233
Protein Accession YP_513914.1
Taxonomy ID 119857
Gene Starting Position 1181397
Gene Ending Position 1182818
Gene Strand (Orientation) +
Protein Name amino acid antiporter
DNA Sequence 
>gi|89255449:1181397-1182818 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGGCTATGACAGTAAATTCATCAGCAAAAGAAAAAATTGGTTTAATTTTACTAGTATTGTTAATGACA
GGAGCTATTGATAATATTAGAAATCTTCCATCTACAGCCACTTCAGGAACATATATATTCTTCTTTTTTG
CAGTAGCTGTTTTTTTATTTTTAGCACCAGTTGCATTAGTATCTGCAGAGATGACTACGACATATACTGC
TAAAGGTGAAGAAGGAGTATATGGTTGGGTTAAAAAAGCTTTTGGCCCTAATGTTGCGATGTTAGCTGTA
TGGTTCCAATGGATAAATACTCTTATCTGGTTTCCAAGTATTTTGACTTTCCTTGCAGGTACAATTGCAT
ACTTATTTAATCCCGATTTTGCACAGAATATAAAATTTACAATTATATTTATAACTGTAGTTTTTTGGTC
TTTGACAATTCTTAATATTAAAGGTCTAAGAGTATCGGCAATTTTCGCTAGTACTTGTACTTTTTTAGGT
ATGGTAATACCGATGTTATTAATGGTGCTATTTGCATTAATTTGGTTACTCAATATCTATGACCTTAATA
TTCATTTTCATTTAAACAATCTAATTCCTAGTTTTACATCTACAGATTCATGGATGGGACTAACAGCGAT
TATAGCTTCTTTCTTAGGACTTGAGTTAGCAACCGTGCATATTAGAAAAGTTATAAATCCTAAAAAAACA
TTTCCTCTAGCACTTTTTATTTCAGTAATATTTATAATCTTTACTATGGTTTTAGGTGCTTTAGCTGTTG
CGATTATATTTCCACAGTCCCAAATTGATGTTGTTCATGGTACTATCAAAACTTTTAAAGTTTATTTAGA
GAGTTTGGGAATACCTGTATTTTTTTATTATATTTTGGGCTTGATGGTTTTTGTTGGTTCAATAGGATCA
ATGATTAACTGGATGATTTCACCTGCAAGAGGATTACTTCAAGCAGCCGATGATCATTTTTTACCAAATA
TGTTAGATAAAACAAATAAGCATGATGTACCAAGTGACATATTAATCCTTCAGGCTATAATTATGACTAT
AATATGTCTGCTTTTAGAATTAGTGCCTTCAGTTCAAGCTTATTATTGGTTGCTTACAGCTCTTAGCACA
CAAATATATTCTTTGATGTATCTAATGATGTTTTTTGCCGCTTTAAAACTAAAACTAACAAATAACCAAA
CTGTAAGAAATACCGATGATTTTCATATCCCTGGTGGGAAAATCGGTATGTCTATTGTTTGTATTTTAGG
TATTATAGGCACTATTTTGTGTGTGATCGTTGGCTTTGTCCCACCAGATAATTTGTATAGTAATCCGCTA
GAGTTTATTGAAATGCTGTCTGTATGTTTTGTATTATCAATTATACCTGTAGTATTCTTTATCATATATA
GAAGAATTAAATTAAAAAATTA
Protein Sequence 
>gi|89256552|ref|YP_513914.1| amino acid antiporter [Francisella tularensis subsp. holarctica LVS] MAMTVNSSAKEKIGLILLVLLMTGAIDNIRNLPSTATSGTYIFFFFAVAVFLFLAPVALVSAEMTTTYTAKGEEGVYGWVKKAFGPNVAMLAVWFQWINTLIWFPSILTFLAGTIAYLFNPDFAQNIKFTIIFITVVFWSLTILNIKGLRVSAIFASTCTFLGMVIPMLLMVLFALIWLLNIYDLNIHFHLNNLIPSFTSTDSWMGLTAIIASFLGLELATVHIRKVINPKKTFPLALFISVIFIIFTMVLGALAVAIIFPQSQIDVVHGTIKTFKVYLESLGIPVFFYYILGLMVFVGSIGSMINWMISPARGLLQAADDHFLPNMLDKTNKHDVPSDILILQAIIMTIICLLLELVPSVQAYYWLLTALSTQIYSLMYLMMFFAALKLKLTNNQTVRNTDDFHIPGGKIGMSIVCILGIIGTILCVIVGFVPPDNLYSNPLEFIEMLSVCFVLSIIPVVFFIIYRRIKLKN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1233 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0531E, under E: Amino acid transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].