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ccpA

Victor ID 4365
Gene Name ccpA
Sequence Strain (Species/Organism) Streptococcus pyogenes MGAS5005
NCBI Gene ID 3572479
NCBI Protein GI 71910237
Locus Tag M5005_Spy_0424
Protein Accession YP_281787.1
Other Database IDs UniProtKB-ID: Q490C6_STRP1
UniRef100: UniRef100_A2RFY8
UniRef90: UniRef90_A1E373
UniRef50: UniRef50_O07329
UniParc: UPI000000B02A
EMBL: CP000017
EMBL-CDS: AAZ51042.1
RefSeq_NT: NC_007297.1
EnsemblGenome: EBSTRG00000028452.
EnsemblGenome_TRS: EBSTRT00000028452
EnsemblGenome_PRO: EBSTRP00000027470
GenomeReviews: CP000017_GR
KEGG: spz:M5005_Spy_0424
HOGENOM: HBG753640
OMA: DDINGKL
ProtClustDB: CLSK698358
BioCyc: SPYO293653:M5005_SPY0424-MONOMER
Taxonomy ID 293653
Gene Starting Position 415391
Gene Ending Position 416392
Gene Strand (Orientation) +
Protein Name catabolite control protein A
DNA Sequence 
>gi|71909814:415391-416392 Streptococcus pyogenes MGAS5005 chromosome, complete genome
AATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTT
AGTCGTGTTGTTAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATC
GCCTTGACTATCGTCCCAATGCTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGT
GATTCCAAATATTGCAAATAGTTATTTTTCTATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTAC
AAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGACAAGGAGGTTAATGTTGTCAATACCCTTT
TTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAAAAATCCGGGCCGAGTTTTC
ACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGCGTCAACATT
GACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGT
CAGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAA
TAAGCTTGACTTCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCG
CAGCGCGTCATTAACTCAGGAGCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAA
ACGGCTTGTTTGAAGCAGGTAAACGCGTACCAGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGT
GGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAACCTGTTTATGACTTAGGTGCTGTTAGCATG
CGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATTCTTTTGAATCATGGTATTA
AAAAACGTGGGACAACTAAGTA
Protein Sequence 
>gi|71910237|ref|YP_281787.1| catabolite control protein A [Streptococcus pyogenes MGAS5005] MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPSVNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ccpA mutant is attenuated in mice (Shelburne et al., 2010).
COG COG1609K, under K: Transcription
References
Shelburne et al., 2010: Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, Brennan RG, Musser JM. A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. PLoS pathogens. 2010; 6(3); e1000817. [PubMed: 20333240].