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sagA from Streptococcus pyogenes MGAS5005

Victor ID 4364
Gene Name sagA from Streptococcus pyogenes MGAS5005
Sequence Strain (Species/Organism) Streptococcus pyogenes MGAS5005
NCBI Gene ID 3572347
NCBI Protein GI 71910375
Locus Tag M5005_Spy_0562
Protein Accession YP_281925.1
Other Database IDs UniProtKB-ID: Q7DAM4_STRP1
UniRef100: UniRef100_A2RFE2
UniRef90: UniRef90_A2RFE2
UniRef50: UniRef50_C0M9J9
UniParc: UPI000000AFB5
EMBL: AE004092
EMBL: CP000017
EMBL-CDS: AAK33684.1
EMBL-CDS: AAZ51180.1
RefSeq_NT: NC_002737.1
RefSeq_NT: NC_007297.1
EnsemblGenome: EBSTRG00000000512.
EnsemblGenome_TRS: EBSTRT00000000512
EnsemblGenome_PRO: EBSTRP00000000512
EnsemblGenome: EBSTRG00000028991.
EnsemblGenome_TRS: EBSTRT00000028991
EnsemblGenome_PRO: EBSTRP00000028009
GenomeReviews: AE004092_GR
GenomeRev
Taxonomy ID 293653
Gene Starting Position 559705
Gene Ending Position 559866
Gene Strand (Orientation) +
Protein Name streptolysin S precursor
DNA Sequence 
>gi|71909814:559705-559866 Streptococcus pyogenes MGAS5005 chromosome, complete genome
TATGTTAAAATTTACTTCAAATATTTTAGCTACTAGTGTAGCTGAAACAACTCAAGTTGCTCCTGGAGGC
TGCTGTTGCTGCTGTACTACTTGTTGCTTCTCAATTGCTACTGGAAGTGGTAATTCTCAAGGTGGTAGCG
GAAGTTATACGCCAGGTAAATA
Protein Sequence 
>gi|71910375|ref|YP_281925.1| streptolysin S [Streptococcus pyogenes MGAS5005] MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQGGSGSYTPGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sagA mutant is attenuated in mice (Betschel et al., 1998).
References
Betschel et al., 1998: Betschel SD, Borgia SM, Barg NL, Low DE, De Azavedo JC. Reduced virulence of group A streptococcal Tn916 mutants that do not produce streptolysin S. Infection and immunity. 1998; 66(4); 1671-1679. [PubMed: 9529097].