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SPs0560

Victor ID 4348
Gene Name SPs0560
Sequence Strain (Species/Organism) Streptococcus pyogenes SSI-1
NCBI Gene ID 1065796
NCBI Protein GI 28895472
Locus Tag SPs0560
Protein Accession NP_801822.1
Other Database IDs UniProtKB-ID: Q8K6K5_STRP3
UniRef100: UniRef100_Q8K6K5
UniRef90: UniRef90_P62561
UniRef50: UniRef50_P62561
UniParc: UPI000000AC8D
EMBL: AE014074
EMBL: BA000034
EMBL-CDS: AAM79908.1
EMBL-CDS: BAC63655.1
RefSeq_NT: NC_004070.1
RefSeq_NT: NC_004606.1
HSSP: P01552
EnsemblGenome: EBSTRG00000034985.
EnsemblGenome_TRS: EBSTRT00000034985
EnsemblGenome_PRO: EBSTRP00000033724
EnsemblGenome: EBSTRG00000035378.
EnsemblGenome_TRS: EBSTRT00000035378
EnsemblGenome_PRO: EBSTRP00000034028
GenomeReviews: AE014074
Taxonomy ID 193567
Gene Starting Position 582445
Gene Ending Position 583200
Gene Strand (Orientation) -
Protein Name SpeA precursor
DNA Sequence 
>gi|28894912:582445-583200 Streptococcus pyogenes SSI-1, complete genome
GTTACTTGGTTGTTAGGTAGACTTCAATTTGGCTTGTGTTTGAGTCAAGCGTTTCATTATCTTTATATAT
CATAAGATATTTAGATTGAGTAAATTCTGGTTCAGGGAAAAAATCAAACCAAAAACTTTCTTTATTCTTA
GGTATGAACTTTATATATCCAGTTTCATATTTAGAAGGTCCATTAGTATATAGTTGCTTATTATCTGTAA
GATATTTTCTAACTTTATAGTCTAATTCTTGAGCAGTTACCATTTTTTTATTTGTTTCAATATCAAATGA
TAGGCTTTGGATACCATCGATTGATACTTTAACGACTATCTTTTTAGGAATTTCTAAATGATTCCCTTCA
TGATTTGTTACCCCTCCGTAGATACATGCACTCCTTTCTGCATTTTCACATAAATAACAGAGATGGTAAT
ATTCTACACCATAAATATCAATGTTTTTATCCTTAAATAAAGTTGCCATCTCTTGGTTCTTAAGTTCAGT
TTTTAATTTATCATAATTTGGCCCTGAAACATTATATATTAAATCGTGAGATAAAAGTTGATCAACAGAT
TTCACATTCTCGTGAGTAACAGGGTCACCCTCATAAAGAAAATATATATTTTGAAGGTTTTTAACTAAAC
TAGATCTGTGAAGTTGGCTTGGATCGGGGTCTTGTTGAGCAAATACCTCTTGCGAGATTGTTAGTCCAAG
AAATGTCACTAAAACAAAAAATACCATTTTCTTCAATACTTTTTTATTGTTTTCCA
Protein Sequence 
>gi|28895472|ref|NP_801822.1| protein SpeA [Streptococcus pyogenes SSI-1] MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNIDIYGVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: SpeA causes pyrexia, hypotension and lethality when administered to rabbits (Lee and Schlievert, 1989).
References
Lee and Schlievert, 1989: Lee PK, Schlievert PM. Quantification and toxicity of group A streptococcal pyrogenic exotoxins in an animal model of toxic shock syndrome-like illness. Journal of clinical microbiology. 1989; 27(8); 1890-1892. [PubMed: 2504778].