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gbs1477

Victor ID 4346
Gene Name gbs1477
Sequence Strain (Species/Organism) Streptococcus agalactiae NEM316
NCBI Gene ID 1030552
NCBI Protein GI 25011519
Locus Tag gbs1477
Protein Accession NP_735914.1
Other Database IDs UniProtKB-ID: Q8E4C4_STRA3
UniRef100: UniRef100_B9UR18
UniRef90: UniRef90_B9UQT2
UniRef50: UniRef50_B9UQV0
UniParc: UPI0000053EAD
EMBL: AL766851
EMBL-CDS: CAD47136.1
RefSeq_NT: NC_004368.1
EnsemblGenome: EBSTRG00000002469.
EnsemblGenome_TRS: EBSTRT00000002469
EnsemblGenome_PRO: EBSTRP00000002387
GenomeReviews: AL732656_GR
KEGG: san:gbs1477
GenoList: gbs1477
HOGENOM: HBG702811
OMA: KITIPQT
ProtClustDB: CLSK447118
BioCyc: SAGA211110:GBS1477-MONOMER
Taxonomy ID 211110
Gene Starting Position 1525910
Gene Ending Position 1527948
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|25010075:1525910-1527948 Streptococcus agalactiae NEM316, complete genome
CTTAAGCTTCCTCTGATTGACGTTTTTTCATGACAACTACTGCTCCAAGCATAATGCTTAAACCAATAAT
TGTGAAAAGAATTGTACCAATACCACCTGTTTGTGGGATGGTTACTTTTTTGTTTTGAACTTGTTGGGCA
TCTTTTTTTACAGATCCTTTATCATATGCGATGTCAGTTGTAGCCCCTTTGCTATATGATGTGGCAGTTA
CTTCAAAGTTTACATCACCTGACAATGTCGCATAACCTGCTGGTGCTTGAGTTTCTTCCAAGCTATAAGT
GCCTTTATCCAAACCAGTAATTTCAAATTGACCACCGGCGTTAGAGATCAATTTAACAACATTATCAGCC
TTTTTATCTGCAACCCATTCATATGAGTAGTTAGCTTTAACAAAAGCGTCATTGTAAGCTTTTTGTTTTT
GATCAACAGTAGCCAATGCTGTTTTACCTTCTTGGCCTTCTTGTTTTTCTTTAGTCAAGTCGTTATAAGC
TTTAACAGCTTCATCCAATGCTAGTTTAGCAGTTTTTACAGCTGCCTTTGCTTCAGCAGTTGCTGCACCT
GCTTTACGTGCCAAGTATTTTCCTTCTTTCTTAACAAGGAAGGTAGCTCCTGCCAAGCGTTCAGTGTTAG
CTTGATTTGTTTTCACAAATTTACGTCCATAAGTCACCACTTTTGGTTCTGATGGGTTGATTGGAGTTGG
ATCATTTGAGTTTTTGTTGTTCTTGATAGTCACAACACCATTTTTAAATGATACATATTCTGGAGTGTAG
CCGCTAACACGTTCGACAACGCGGTAAGTTTTAGTATTATCCAAACCTGTGAAAGTATGTTCAAAGCGTG
ATGGTTTTGTTGCTTCGTGTGAAGCAACGTTCACCCATGTACCATCCGTTTGTTTTTCTTGCAAGGTAAA
GATAGCTTTAACTGCAACATTAACATCAGTAATTGTACCATCTACTGCCCAGTCTTTAATGACTTTAATT
TCTTGGTTAGCTGGAGTACCTTCTTGTGGTTCACTTTCTTCCGTTGGGTTATTACCATAGTCCAATTTAA
CATCATTGGTTTCTGGAACTTCAACAGTAGTGGAGCCGTTCACCGTAGCTGAGTAAGTGATCTTGATTTC
AACATCTTTGTCTTTTGCAGCAGCTGCTACTGCTGCAAGACCTGTTGCATTCAAGGCAAGACGGAAACCT
TGGTCATCTGTTACGAGTTTGTAGTTTAAAACAGGAAAATCTTTACCATCCAATGTTACTTTAACGTTGT
TGTTGAACGTCAAACCTTTAGTCATGCTATCAGTCCAAACCAGTTTCTTATAGTCTGAGCCTTTAAGAAT
TTTTGTTCCAACTATGTATTCTTTTTTGTCACCAACTGTCGCTGAGACAACACCTTTGTCTTTTCGGTTG
TCAGTATAATCAAGATCTTTATCTGCAAAGTTCTTATCTACTTGTGGTTTTGTTTCAGTATTCTTTGGAT
AAATGTGAGCATCTTTAACAACACCTTGGTTGTTTACCAATGGCAGAGTGATTTTAACTGGAACTGCTTT
TGAATCAGCCAAGATAGAACCGTTGTTATCGTAGTTTGATTTTTCTTTCAATTCAACGATTTGGTAAGTT
CCTTTTAACTTAGCAGTGTTAAAAGCAAAACCAGTGTCTTTTGTTAACCCTGAAAGAACAGCACCACCTT
CAGCATCTTTAGCTTCCAAAGTATCGACTTCCTTACCATTTTCAGTAATGAATTTTGTACCAGTTTCATT
TTTGAAAACAAAGAAAGCACCCTTAATTTCTTTAGCATCGGTTGAGCCAAAATAAGATTTAAGGTCATTA
ATTTGTTTACCAACATAATCGCTATCATTCTTACCTTTTGTACCTTCAGTAAAGTTATCAAATGCAGCTT
GTGGCATGACAATCTTGTGCAAGGTCACAGTATCAGTTGTTACGTCGTCCGCAAACGCTGGTGCAACTGA
GAATAGTGACGTTAAGATCAATAGCAGTGTCGAGAACACTGTAAGACATTTGTTGATTTTTTTCATTTCT
ATCTCCTTC
Protein Sequence 
>gi|25011519|ref|NP_735914.1| hypothetical protein gbs1477 [Streptococcus agalactiae NEM316] MKKINKCLTVFSTLLLILTSLFSVAPAFADDVTTDTVTLHKIVMPQAAFDNFTEGTKGKNDSDYVGKQINDLKSYFGSTDAKEIKGAFFVFKNETGTKFITENGKEVDTLEAKDAEGGAVLSGLTKDTGFAFNTAKLKGTYQIVELKEKSNYDNNGSILADSKAVPVKITLPLVNNQGVVKDAHIYPKNTETKPQVDKNFADKDLDYTDNRKDKGVVSATVGDKKEYIVGTKILKGSDYKKLVWTDSMTKGLTFNNNVKVTLDGKDFPVLNYKLVTDDQGFRLALNATGLAAVAAAAKDKDVEIKITYSATVNGSTTVEVPETNDVKLDYGNNPTEESEPQEGTPANQEIKVIKDWAVDGTITDVNVAVKAIFTLQEKQTDGTWVNVASHEATKPSRFEHTFTGLDNTKTYRVVERVSGYTPEYVSFKNGVVTIKNNKNSNDPTPINPSEPKVVTYGRKFVKTNQANTERLAGATFLVKKEGKYLARKAGAATAEAKAAVKTAKLALDEAVKAYNDLTKEKQEGQEGKTALATVDQKQKAYNDAFVKANYSYEWVADKKADNVVKLISNAGGQFEITGLDKGTYSLEETQAPAGYATLSGDVNFEVTATSYSKGATTDIAYDKGSVKKDAQQVQNKKVTIPQTGGIGTILFTIIGLSIMLGAVVVMKKRQSEEA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gbs1477 (pilB) mutant had significantly reduced invasion of hBMECs (Maisey et al., 2007).
References
Maisey et al., 2007: Maisey HC, Hensler M, Nizet V, Doran KS. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. Journal of bacteriology. 2007; 189(4); 1464-1467. [PubMed: 17041051].