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lmb from Streptococcus agalactiae NEM316

Victor ID 4343
Gene Name lmb from Streptococcus agalactiae NEM316
Sequence Strain (Species/Organism) Streptococcus agalactiae NEM316
NCBI Gene ID 1030333
NCBI Protein GI 25011353
Locus Tag gbs1307
Protein Accession NP_735748.1
Other Database IDs UniProtKB-ID: Q8E4U0_STRA3
UniRef100: UniRef100_B5XIS2
UniRef90: UniRef90_Q1J4I1
UniRef50: UniRef50_B4U552
UniParc: UPI000005392D
EMBL: AL766850
EMBL-CDS: CAD46966.1
RefSeq_NT: NC_004368.1
EnsemblGenome: EBSTRG00000001926.
EnsemblGenome_TRS: EBSTRT00000001926
EnsemblGenome_PRO: EBSTRP00000001844
GenomeReviews: AL732656_GR
KEGG: san:gbs1307
GenoList: gbs1307
HOGENOM: HBG731008
OMA: CGASNDK
ProtClustDB: CLSK877302
BioCyc: SAGA211110:GBS1307-MONOMER
Taxonomy ID 211110
Gene Starting Position 1350555
Gene Ending Position 1351485
Gene Strand (Orientation) -
Protein Name laminin-binding surface protein
DNA Sequence 
>gi|25010075:1350555-1351485 Streptococcus agalactiae NEM316, complete genome
TTTACTTCAACTGTTGATAGAGCACTTCCAAATTTGCTCTAAGATTTTCTAGATATGTCTTGTTTCCGCT
TGGAGCAGCTTCAAGTGGACTTAATGTCTTTACTTTAGCTCCTGTTGATTTCGCAATAGCATGAGCAATT
TTGGGATTGACGTTGTCTTCTGCAAAAATAGTCTTGACGTTGTATTCTTTGACAAAGTCTTGAATTTCTT
TCAATTGGCGAGGAGAGGGCTCTTGCTCTGGAGAAATACCCGAGATACCAAGTTGTTTCAAGCCGAATCG
TTTAGCCAGATAAGAAAATGCCGTGTGTTGCGTCACGAATGTTTTTGAGCGCACCTTTTTAAATTTTTGA
GTGTATTCTTCAGTTAGTTGCTCTGCTTCTTTTTTGAAAGCCTTAGCCTTTTTAGTGTAACTGTCTTTGT
GTTTAGGATCCAAACGTCCTAGCTCTTTAGCGATATTAACAGCTTCCTCACCAGCTAAAACGGGATCCGT
CCAGGTATGTGGGTCATAAAGTGTCGCAGGGTCAATGCCTTGTGTGACTTCCATATCTTCTAGCCCTTTG
ACTCTATCTAGTGTCAAAGGTTTTGACGCTTCAAACACATCAACCTTTGATTTTTTTAAATTAGGGTCTA
GATCCCTTGCCCAAGCTTCTAAGGTATGTGAATGGTAAACAAACAAATCCGCGTCATAAATAGCTGCCAC
ATCATTTACAGACGGTTCAAAGGAATGAATGCCTGCACCTGATTGGATCATCCTCACATCATTGAGGTCT
CCAGATACTTCTTTTGTCATCGCATACATTGGGTAAAAGCTGGTTACAACTGACATGCCTTGCGTAGGCT
GTTTGGGGTTTGCTGACTTATCACACCCTGCTATCATTACTAAACTCACAACCATAGCCATGAGAAAAAA
ACCTTTTTTCATAGTACCTCC
Protein Sequence 
>gi|25011353|ref|NP_735748.1| laminin-binding surface protein [Streptococcus agalactiae NEM316] MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lmb mutant has reduced invasion of human brain microvascular endothelial cells compared to wildtype (Tenenbaum et al., 2007).
COG COG0803P, under P: Inorganic ion transport and metabolism
References
Tenenbaum et al., 2007: Tenenbaum T, Spellerberg B, Adam R, Vogel M, Kim KS, Schroten H. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein Lmb. Microbes and infection / Institut Pasteur. 2007; 9(6); 714-720. [PubMed: 17400016].