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lmb from Streptococcus agalactiae 2603V/R

Victor ID 4338
Gene Name lmb from Streptococcus agalactiae 2603V/R
Sequence Strain (Species/Organism) Streptococcus agalactiae 2603V/R
NCBI Gene ID 1014041
NCBI Protein GI 22537388
Locus Tag SAG1234
Protein Accession NP_688239.1
Other Database IDs UniProtKB-ID: Q8DZ80_STRA5
UniRef100: UniRef100_Q9ZHG8
UniRef90: UniRef90_Q1J4I1
UniRef50: UniRef50_B4U552
UniParc: UPI00000B30F0
EMBL: AE009948
EMBL-CDS: AAN00112.1
RefSeq_NT: NC_004116.1
EnsemblGenome: EBSTRG00000006383.
EnsemblGenome_TRS: EBSTRT00000006383
EnsemblGenome_PRO: EBSTRP00000006050
GenomeReviews: AE009948_GR
KEGG: sag:SAG1234
TIGR: SAG1234
HOGENOM: HBG731008
OMA: CGASNDK
ProtClustDB: CLSK877302
BioCyc: SAGA208435:SAG_1234-MONOMER
Taxonomy ID 208435
Gene Starting Position 1243495
Gene Ending Position 1244415
Gene Strand (Orientation) -
Protein Name laminin-binding surface protein
DNA Sequence 
>gi|22536185:1243495-1244415 Streptococcus agalactiae 2603V/R, complete genome
TTTACTTCAACTGTTGATAGAGCACTTCCAAATTTGCTCTAAGATTTTCTAGATATGTCTTGTTTCCGCT
TGGAGCAGCTTCAAGTGGACTTAATGTCTTTACTTTAGCTCCTGTTGATTTCGCAATAGCATGAGCAATT
TTGGGGTTGACGTTGTCTTCTGCAAAAATAGTCTTGACGTTGTATTCTTTAACAAAGTCTTGAATTTCTT
TCAATTGGCGAGGAGAGGGCTCTTGCTCTGGAGAAATACCCGAGATACCAAGTTGTTTCAAGCCGAATCG
TTTAGCCAGATAAGAAAATGCCGTGTGTTGCGTCACAAATGTTTTTGAGCGCACCTTTTTAAATTTTTGA
GTGTATTCTTCAGTTAGTTGCTCTGCTTCTTTTTTGAAAGCCTTAGCCTTTTTAGTGTAACTGTCTTTGT
GTTTAGGATCCAAATGTCCTAGCTCTTTAGCGATATTAACAGCTTCCTCACCAGCTAAAACGGGATCCGT
CCAGGTATGTGGGTCATAAAGTGTCGCAGGGTCAATGCCTTGTGTGACTTCCATATCTTCTAGCCCTTTG
ACTCTATCTAGTGTCAGAGGTTTTGACGCTTCAAACACATTAACCTTTGATTTTTTTAAATTAGGGTCTA
GATCCCTTGCCCAAGCTTCTAAGGTATGTGAATGGTAAACAAACAAATCCGCGTCATAAATAGCTGCCAC
ATCATTTACAGACGGTTCAAAGGAATGAATGCCTGCACCTGATTGGATCATCCTCACATCATTTAGGTCT
CCAGATACTTCTTTTGTCATCGCATACATTGGGTAAAAGCTGGTTACAACTGACATGCCTTGCGTAGGCT
GTTTGGGGTTTGCTGACTTATCACACCCTGCTATCATTACTAAACTCACAACCATAGCCATGAGAAAAAA
AACTTTTTTCA
Protein Sequence 
>gi|22537388|ref|NP_688239.1| laminin-binding surface protein [Streptococcus agalactiae 2603V/R] MKKVFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVNVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGHLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lmb mutant has reduced invasion of human brain microvascular endothelial cells compared to the wildtype (Tenenbaum et al., 2007).
COG COG0803P, under P: Inorganic ion transport and metabolism
References
Tenenbaum et al., 2007: Tenenbaum T, Spellerberg B, Adam R, Vogel M, Kim KS, Schroten H. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein Lmb. Microbes and infection / Institut Pasteur. 2007; 9(6); 714-720. [PubMed: 17400016].