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salT

Victor ID 4329
Gene Name salT
Sequence Strain (Species/Organism) Streptococcus pyogenes MGAS315
NCBI Gene ID 1009964
NCBI Protein GI 21911185
Locus Tag SpyM3_1649
Protein Accession NP_665453.1
Other Database IDs UniProtKB-ID: Q7CEQ8_STRP3
UniRef100: UniRef100_Q7CEQ8
UniRef90: UniRef90_E0PU23
UniRef50: UniRef50_Q1J4R0
UniParc: UPI000011E560
EMBL: AE014074
EMBL-CDS: AAM80256.1
RefSeq_NT: NC_004070.1
EnsemblGenome: EBSTRG00000034542.
EnsemblGenome_TRS: EBSTRT00000034542
EnsemblGenome_PRO: EBSTRP00000033281
GenomeReviews: AE014074_GR
KEGG: spg:SpyM3_1649
HOGENOM: HBG698018
OMA: ERIISIW
ProtClustDB: CLSK452366
BioCyc: SPYO198466:SPYM3_1649-MONOMER
Taxonomy ID 198466
Gene Starting Position 1659727
Gene Ending Position 1661211
Gene Strand (Orientation) -
Protein Name putative salivaricin A modification enzyme
DNA Sequence 
>gi|21909536:1659727-1661211 Streptococcus pyogenes MGAS315 chromosome, complete genome
TTCATTTTGCCTCTTCCTCCTGATATTTATTCATATACGAGTCATATAAGTCACAATAATCCTTATTATT
TTTGTACAAATAATGATGGTTTCCATAGTCAATAATTTTGCCATTATCCATTATTAAAATCTTATCAGCT
TTTTCAACTGTATTAAGTCTATGGGTAACCAAAACCCTCGTACAATGTAAAGCCTCAACATTTTTTTGGA
TTATTCTTTCAGTTTTTACATCTAAAGCTGATGTAGGTTCATCAAGAACTAAGATTCTAGGGGTAGTTAC
TAACTCTCTTGCTAAAGAAATTCGTTGTTTTTGCCCCCCAGATAGTGATGGATTATCTCGAAAAAGTGGA
GTATGAAACTTCATTGGCATACTCCTGATATCCTCATATAGTGATACCCTTTTACAAGTTTCAATAACCT
GTTCTCCTGAAACAGATTCTCTCCCTAGCGAAATGTTATACATCACATCCCCATCAAATATGGGAGAATC
TTGAGATACAAAAGCCGATATATTCCTAAAATCAGTTTTATCAATTTTAGAGTAGGATATATTGTTGTAT
GTGATGTCTCCACTACTAGGGCTTACATAGCCTAACAACATCTTAGCTAGAGTTGTCTTTCCACTTCCAC
TTTTCCCTATAATTGCAACAAATTCTCCTGAATGGACTTTTAGGTTTATTCCATTTAACACCTCTGCCCC
ATTTAACTCATATTGATAGTTTATATTTTCTAAATTTATCTCTATATCTGTATCCTCTGATAGCTTATAA
GTGCCATTCGTCTCATCATCAAGAGTTGATATCTCTAATACCCTTTCGTAATGCTTAACACCATATAGAA
TCTCATCAATCGAATTCAAAATATTATTAATGGGATTAATAATATTTAAAACCATCATATAAAGAAGAAT
AAGCTCACCACTGCTACTATTTGGTGAATAATATAGAAATAACAGAATTAACAAAATAGGTATGGAAAAA
GTTATCACATAATTTACTGCTCCTAAAAGATTGAAATATCTATTTCTATCATATGTTGAATTGATATAGT
CCTTAAAACTTTTATCCCATTTTGACAAAAGTTCTTTTTCAGAATTTTTAGCTTTAAAAAGAAATAGCCC
GTCCATCAGTGAAAAAAATGTTTGTAAAGAGTTCTTTTGTCTTAAAACTTCTTTACCTAACTTTTCTTGT
TTAATGCTTAGTGATAGGAAAAAAATCATCATTTCTACAATAAAAACTATACACAATATAACTCCCAAAG
GTGTAGAAACATATGTGATATAACTAATACTCGCAAACATTAAGATAATATCCAACCAGATAGAAATAAT
TCTTTCTGATAGTAACTCCCTCACAATCATCAAACCATTATATCTATGAATGATGTCTGTTTTATCTATT
TTTCCAATATATTCTATGGGAAGTTTCAATAACTTAGTCACAAACTTTTCTGAAATAGTGCTGTGAAATT
TATTTTGCAATTTCA
Protein Sequence 
>gi|21911185|ref|NP_665453.1| salivaricin A modification enzyme [Streptococcus pyogenes MGAS315] MKLQNKFHSTISEKFVTKLLKLPIEYIGKIDKTDIIHRYNGLMIVRELLSERIISIWLDIILMFASISYITYVSTPLGVILCIVFIVEMMIFFLSLSIKQEKLGKEVLRQKNSLQTFFSLMDGLFLFKAKNSEKELLSKWDKSFKDYINSTYDRNRYFNLLGAVNYVITFSIPILLILLFLYYSPNSSSGELILLYMMVLNIINPINNILNSIDEILYGVKHYERVLEISTLDDETNGTYKLSEDTDIEINLENINYQYELNGAEVLNGINLKVHSGEFVAIIGKSGSGKTTLAKMLLGYVSPSSGDITYNNISYSKIDKTDFRNISAFVSQDSPIFDGDVMYNISLGRESVSGEQVIETCKRVSLYEDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALDVKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDYCDLYDSYMNKYQEEEAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: salT mutant is attenuated in zebrafish (Kizy and Neely, 2009).
COG COG2274V, under V: Defense mechanisms
References
Kizy and Neely, 2009: Kizy AE, Neely MN. First Streptococcus pyogenes signature-tagged mutagenesis screen identifies novel virulence determinants. Infection and immunity. 2009; 77(5); 1854-1865. [PubMed: 19223485].