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SpyM3_0013

Victor ID 4322
Gene Name SpyM3_0013
Sequence Strain (Species/Organism) Streptococcus pyogenes MGAS315
NCBI Gene ID 1008327
NCBI Protein GI 21909549
Locus Tag SpyM3_0013
Protein Accession NP_663817.1
Other Database IDs UniProtKB-ID: Q8K8Z2_STRP3
UniRef100: UniRef100_Q879R6
UniRef90: UniRef90_Q1J947
UniRef50: UniRef50_B4U5I2
UniParc: UPI00000DA976
EMBL: AE014074
EMBL-CDS: AAM78620.1
RefSeq_NT: NC_004070.1
EnsemblGenome: EBSTRG00000033559.
EnsemblGenome_TRS: EBSTRT00000033559
EnsemblGenome_PRO: EBSTRP00000032298
GenomeReviews: AE014074_GR
KEGG: spg:SpyM3_0013
HOGENOM: HBG727793
OMA: EGGFFPY
ProtClustDB: CLSK876990
BioCyc: SPYO198466:SPYM3_0013-MONOMER
Taxonomy ID 198466
Gene Starting Position 15109
Gene Ending Position 16500
Gene Strand (Orientation) +
Protein Name putative amino acid permease
DNA Sequence 
>gi|21909536:15109-16500 Streptococcus pyogenes MGAS315 chromosome, complete genome
CATGACTATTTTTCGTAAAAAAAAGAAATATTCCAATAAAACAGAAATGCAAAGGCACTTCAAAGTTATT
GATTTAATTTTTTTAGGCCTAGGTTCAATGGTTGGAACAGGTATCTTTACAGTTACTGGCATAGGCGCTG
CTAAGTATGCAGGTCCTGCTTTAACAATATCGATTATCATTTCCGCGATTGCTATTGGAATTTTAGCCTT
ATTTTATGCAGAATTTGCGTCTCGTATGCCTTCTAACGGTGGTGCTTATAGTTATGTTTATGCAACCTTG
GGAGAGTTTCCAGCATGGCTTGTTGGCTGGTATATTATTATGGAATTTTTAACAGCTATATCTAGTGTTG
CTGTTGGCTGGGGAAGTTATTTAAAAGGATTGCTTGCCAATTATAATATAGTATTACCAAACGCTTTAAA
TGGCACGTTCAATCTTAAGAATGGAACTTACATAGATATTCTTCCTGTTTTAGTGATGTTTTTCGTGACA
GGGATTGTCCTAATGAATTCGAAATTAGCCCTGAGATTCAATAGTTTTTTAGTTATTTTAAAATTTTCAG
CACTGGCTTTATTTATCTTTGTAGGCATTTTTTTTATTGATCACAATAATTGGTTTCATTTTGCTCCATA
TGGTGTAGGACAAATTACTGGAGGTAAAACAGGTATATTTGCTGGTGCTTCTGTTATGTTCTTTGCATTT
TTAGGATTTGAATCTATTTCAATGGCAGTTGATGAAGTGAAAGAACCACAAAAAACAATCCCTAAAGGCA
TCATTTTATCTTTGATTATTGTAACAGCACTCTATATAGTTGTCACCACTATTTTAACGGGAATTGTACA
CTACACTAAATTAAATGTTCCAGACGCGGTGGCTTTTGCTTTAAGAAATATTAGACTTTATTGGGCAGCT
GACTATGTGTCGATAGTTGCTATTTTGACTCTTATTACGGTATGTATTTCTATGACCTATGCATTAGCTA
GAACAATTTACAGTATTAGTAGAGATGGTTTATTACCTAAATCACTTTATACTCTCACTAAAAAAAATAA
AGTGCCTCAAAATGCTACTCTTGTCACTGGACTACTTGCTATGATTTGTGCGGGAATATTTCCTTTATCG
AGTCTAGCAGAGTTTGTTAATATTTGTACTTTAGCATATTTAATTATTCTGTCGGGTGCAATTATTAAAC
TCAGAAGAATAGAAGGAGAACCAAAAGCAAATGAATTTAAAACTCCTCTAGTACCATTCCTACCAATGTT
GGCAATTATCATTTGTCTATCATTTATGAGCCAATATAAAGCTTTTACTTGGATTGCTTTTGCTATTGCC
ACAATTATTGGAACATTAATCTACTTAGCTTATGGTTATACTCATTCAATAGAAAATAAATA
Protein Sequence 
>gi|21909549|ref|NP_663817.1| amino acid permease [Streptococcus pyogenes MGAS315] MTIFRKKKKYSNKTEMQRHFKVIDLIFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMFFVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWFHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SpyM3_0013 mutant is attenuated in zebrafish (Kizy and Neely, 2009).
COG COG0531E, under E: Amino acid transport and metabolism
References
Kizy and Neely, 2009: Kizy AE, Neely MN. First Streptococcus pyogenes signature-tagged mutagenesis screen identifies novel virulence determinants. Infection and immunity. 2009; 77(5); 1854-1865. [PubMed: 19223485].