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mprF from Staphylococcus aureus subsp. aureus MRSA252

Victor ID 4312
Gene Name mprF from Staphylococcus aureus subsp. aureus MRSA252
Sequence Strain (Species/Organism) Staphylococcus aureus subsp. aureus MRSA252
NCBI Gene ID 2861306
NCBI Protein GI 49483553
Locus Tag SAR1372
Protein Accession YP_040777.1
Other Database IDs UniProtKB-ID: MPRF_STAAR
UniRef100: UniRef100_Q6GH45
UniRef90: UniRef90_Q2G2M2
UniRef50: UniRef50_Q99UB9
UniParc: UPI00003B165A
EMBL: BX571856
EMBL-CDS: CAG40370.1
RefSeq_NT: NC_002952.2
EnsemblGenome: EBSTAG00000021761
EnsemblGenome_TRS: EBSTAT00000021762
EnsemblGenome_PRO: EBSTAP00000021098
GenomeReviews: BX571856_GR
KEGG: sar:SAR1372
eggNOG: COG2898
HOGENOM: HBG694561
OMA: WEPRYMA
ProtClustDB: CLSK885299
BioCyc: SAUR282458:SAR1372-MONOMER
Taxonomy ID 282458
Gene Starting Position 1427046
Gene Ending Position 1429568
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|49482253:1427046-1429568 Staphylococcus aureus subsp. aureus MRSA252 chromosome, complete genome
AATGAATCAGGAAGTTAAAAACAAAATATTTTCAATCTTAAAAATTACGTTTGCTACAGCTTTATTTATT
TTTGTAGTAATCACGTTGTATCGAGAGTTATCTGGGATTAACTTTAAAGATACTTTGGTTGAATTTAGTA
AAATCAACCGTATGTCCCTTGTCTTATTATTTATTGGTGGTGGGGCATCGCTTGTTATTCTCTCAATGTA
TGATGTGATTTTATCTAGAGCTTTAAAAATGGATATTTCATTAGGAAAAGTTTTAAGAGTAAGTTATATC
ATTAATGCATTAAATGCGATTGTAGGCTTTGGTGGCTTTATTGGTGCCGGTGTAAGAGCAATGGTTTACA
AAAACTATACGCATGATAAAAAGAAATTGGTTCACTTTATTTCATTAATACTGATTTCAATGTTGACAGG
TTTAAGTTTGTTATCATTGTTAATCGTATTCCATGTTTTTGATGCATCATTAATTTTAAATAAAATTACG
TGGGTGAGATGGGTACTTTATGCTGTGTCGTTGTTCTTACCATTATTTATTATATATTCAATGGTTAGAC
CGCCCGATAAAAACAATCGTTATGTAGGCTTGTATTGTACATTAGTGTCATGTGTGGAATGGTTAGCCGC
TGCAGTTGTATTATACTTCTGTGGTGTCATAGTTGACGTCCATGTCTCATTTATGTCATTTATTGCAATA
TTCATTATTGCTGCATTATCTGGATTAGTCAGCTTTATTCCAGGTGGTTTTGGTGCCTTCGACTTAGTTG
TTTTATTAGGCTTTAAAACGTTAGGTGTACCTGAAGAAAAAGTATTATTAATGCTACTACTTTATCGCTT
TGCGTACTATTTCGTACCAGTGATTATTGCATTAATCCTTTCATCATTTGAGTTTGGTACTTCAGCTAAG
AAATATATTGAAGGATCTAAATATTTCATTCCGGCTAAAGATGTGACATCGTTTTTAATGTCGTATCAAA
AAGATATTATTGCTAAAATACCATCATTATCATTGGCAATTTTAGTATTCTTTACAAGTATGATTTTCTT
TGTAAATAATTTGACGATTGTATACGATGCTTTATATGATGGCAATCATTTAACGTATTATCTTTTATTG
GCAATACATACAAGTGCCTGTTTATTACTTTTACTTAATGTTGTAGGTATTTATAAACAAAGTAGACGTG
CCATTATTTATGCAATGATTTCGATTATCTTAATTATTGTCGCGACGTTATTCACTTATGCGTCATACAT
TTTAATAACTTGGTTAGTTATTATCTTTGCTTTACTTATTGTTGCTTTCCGTAGAGCACGTAGGTTAAAA
CGTCCAATTCGAATGAGAAATCTAGTCGCAATGCTTTTGTTCAGCATATTTATACTCTACATCAACCATA
TATTTATAGCTGGAACATTTTATGCTTTAGATGTTTATACAATCGAAATGCATACGTCTGTACTTAAATA
TTATTTCTGGATTACCATTTTAATTATCGCAATTATTGTTGGTGCAATTGCGTGGTTATTCGATTATCAA
TTTAGTAAAGTGCGTATATCTTCTAATATTGAAGAGTGCGAAGAGATTATTGATCAATATGGTGGGAATT
ATTTAAGTCATTTAATTTATAGTGGTGATAAACAGTTCTTTACTAATGAAGATAAAAATGCATTTTTAAT
GTATCGCTATAAAGCAAGTTCGTTAGTAGTTCTTGGCGATCCAATCGGTGATGAAAATGCCTTTGATGAA
TTGTTAGAAGCATTCTATAATTACGCTGAGTATTTAGGCTATGATGTTATATTCTATCAAGTTACAGATC
AACACATGCCTTTATATCATAATTTCGGCAACCAATTTTTCAAATTAGGTGAAGAAGCAATTATTGATTT
AACGCAATTTTCAACTTCAGGTAAAAAACGCCGTGGATTTAGAGCGACTTTAAACAAATTCGATGAACTT
AATATTTCATTCGAAATTATTGAACCACCGTTTTCAACTGAATTTATAAATGAACTTCAACATGTCAGTG
ATTTGTGGTTAGATAATCGTCAGGAAATGCATTTCTCTGTTGGTCAATTTAATGAAACATATTTATCTAA
AGCGCCAATTGGTGTGATGCGCAATGAAAATAATGAAGTAATTGCATTTTGTAGTTTAATGCCAACATAC
TTTAATGATGCCATTTCAGTCGATTTAATTAGATGGTTGCCAGAGTTAGATTTACCGTTAATGGATGGAT
TATACTTGCACATGTTACTTTGGAGTAAAGAACAAGGTTATACAAAATTTAATATGGGTATGGCAACGTT
ATCGAACGTTGGTCAATTGCATTATTCATATTTAAGAGAAAGACTTGCAGGTCGTGTCTTTGAACATTTC
AACGGTCTATATCGTTTCCAAGGATTACGTCGTTATAAATCTAAATATAATCCGAATTGGGAACCACGCT
TTTTAGTTTATCGTAAAGATAATTCGCTTTGGGAATCACTTTCTAAAGTAATGCGTGTAATACGTCACAA
ATA
Protein Sequence 
>gi|49483553|ref|YP_040777.1| hypothetical protein SAR1372 [Staphylococcus aureus subsp. aureus MRSA252] MNQEVKNKIFSILKITFATALFIFVVITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILNKITWVRWVLYAVSLFLPLFIIYSMVRPPDKNNRYVGLYCTLVSCVEWLAAAVVLYFCGVIVDVHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIPSLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYLLLAIHTSACLLLLLNVVGIYKQSRRAIIYAMISIILIIVATLFTYASYILITWLVIIFALLIVAFRRARRLKRPIRMRNLVAMLLFSIFILYINHIFIAGTFYALDVYTIEMHTSVLKYYFWITILIIAIIVGAIAWLFDYQFSKVRISSNIEECEEIIDQYGGNYLSHLIYSGDKQFFTNEDKNAFLMYRYKASSLVVLGDPIGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGQFNETYLSKAPIGVMRNENNEVIAFCSLMPTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mprF mutant is attenuated in mice (Peschel et al., 2001).
COG COG2898S, under S: Function unknown
References
Peschel et al., 2001: Peschel A, Jack RW, Otto M, Collins LV, Staubitz P, Nicholson G, Kalbacher H, Nieuwenhuizen WF, Jung G, Tarkowski A, van Kessel KP, van Strijp JA. Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine. The Journal of experimental medicine. 2001; 193(9); 1067-1076. [PubMed: 11342591].