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FTL_0616

Victor ID 430
Gene Name FTL_0616
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3951342
NCBI Protein GI 89256013
Locus Tag FTL_0616
Protein Accession YP_513375.1
Taxonomy ID 119857
Gene Starting Position 606073
Gene Ending Position 607026
Gene Strand (Orientation) +
Protein Name DNA-directed RNA polymerase subunit alpha
DNA Sequence 
>gi|89255449:606073-607026 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGGCATTAGAAAATTTACTACATCCTACTAATATTAAAATTGATGAATATGCTAAAAATGCTACTAAG
TTTTCTTTTGAAGCCCTAGAGAGAGGGGTAGGTTATACACTTGGGTTTGCTCTTAAGCAAACTATGCTTT
ACTCTATTGCTGGTGCATGTGTTACTAGTATAAAAATTAATGATGGTAAAGTTACTTCTTTAGAAGATGT
GATTCCATGTGATGAGACAGTTGCTGATATTATCCTGAACGTTAAATCTCTGTCTGTAACTTTAGCAGAA
GATGTTGAAACGGGGACAATAACTTTTGAACTATCAGGCTCGGAAGAAGAAATTTTTTCAGAAGAAGCTA
AGCTATCTGAAGGTTTGGCAATAACTGAAGAAGTATTTATCTGTAGTTACAATGGTGGTAAAAAGCTAAA
AATAGAAGCTAAAGTAGAAAAAGGCGTAGGCTTTAGACCTGCACAAGATAATTTTAAGGATGGTGAGTTC
CTTTTAGATGCGACTTTCTCACCTGTTGTTTTTTGTGATTTTGAGATTAAAGATGCTCGTGTTGGTAGAC
GTACGGATCTTGATAAGCTTGAGCTTAATATTAAAACAAATGGTAATGTGAATTGCGAGGAAGCTTTAAG
ACTAGCAGCTACTAAAATCCAAAATCAATTAAGAAATATCGTAGATATTGAAGAGATTAATAAGGGTATT
TTTGTAGAAGATCCTAAAGATATAAATCCTATTTTATTAAAGCATGTTGAAGAATTAAATCTAACAGCTA
GATCTTCTAATTGCTTAAAAGCTGTAAATATTAGACTAATTGGTGAGTTAGTACAGAAGACAGAAAACGA
ACTTCTTAAAGCACCAAATTTTGGTAAAAAATCATTAACAGAGATCAAAGACAAGTTGTCTGAGCTTGGT
TTATCTTTAGGAACTCTTATCGAAAATTGGCCTCAAGATTTATA
Protein Sequence 
>gi|89256013|ref|YP_513375.1| DNA-directed RNA polymerase subunit alpha [Francisella tularensis subsp. holarctica LVS] MALENLLHPTNIKIDEYAKNATKFSFEALERGVGYTLGFALKQTMLYSIAGACVTSIKINDGKVTSLEDVIPCDETVADIILNVKSLSVTLAEDVETGTITFELSGSEEEIFSEEAKLSEGLAITEEVFICSYNGGKKLKIEAKVEKGVGFRPAQDNFKDGEFLLDATFSPVVFCDFEIKDARVGRRTDLDKLELNIKTNGNVNCEEALRLAATKIQNQLRNIVDIEEINKGIFVEDPKDINPILLKHVEELNLTARSSNCLKAVNIRLIGELVQKTENELLKAPNFGKKSLTEIKDKLSELGLSLGTLIENWPQDL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0616 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0202K, under K: Transcription
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].