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mxiD from Shigella flexneri 5a

Victor ID 43
Gene Name mxiD from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876512
NCBI Protein GI 13449092
Locus Tag pWR501_p153
Protein Accession NP_085308.1
Other Database IDs UniProtKB-ID: MXID_SHIFL
UniRef100: UniRef100_Q04641
UniRef90: UniRef90_Q04641
UniRef50: UniRef50_Q04641
UniParc: UPI000012FAAC
EMBL: X67206
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: CAA47644.1
EMBL-CDS: CAC05820.1
EMBL-CDS: AAK18464.1
EMBL-CDS: AAL72331.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
PDB: 2JW1
DIP: DIP-45187N
EnsemblGenome: EBESCG00000093062
EnsemblGenome_TRS: EBESCT00000094018
EnsemblGenome_PRO: EBESCP00000090225
GenomeReviews: AF386526_GR
KEGG: sfl:CP0145
HOGENOM
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 116974
Gene Ending Position 118674
Gene Strand (Orientation) +
Protein Name Type III secretion protein
DNA Sequence 
>gi|13448939:116974-118674 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
AATGAAAAAATTTAATATTAAATCTTTGACTCTCTTGATTGTATTGTTACCATTGATAGTTAATGCTAAT
AATATTGACTCTCATTTATTAGAACAAAATGACATAGCGAAATATGTTGCTCAAAGTGATACGGTAGGAT
CTTTTTTTGAACGTTTTTCTGCGTTATTAAATTATCCTATTGTTGTTAGCAAACAAGCTGCAAAAAAGAG
AATATCTGGGGAGTTTGATTTATCTAATCCAGAAGAAATGCTTGAAAAACTGACATTACTTGTGGGACTC
ATATGGTATAAAGATGGAAATGCATTATACATATATGACTCTGGAGAATTAATAAGCAAAGTTATTTTGC
TGGAGAATATATCACTTAATTATCTTATTCAGTATCTGAAGGATGCTAACCTTTATGATCACAGATATCC
TATAAGAGGAAACATTAGTGATAAAACATTCTATATATCTGGTCCTCCGGCATTGGTTGAACTGGTAGCT
AATACAGCAACTTTGCTTGATAAGCAGGTTTCTTCTATTGGGACAGATAAAGTTAATTTTGGGGTTATAA
AATTAAAAAATACATTTGTTAGTGACAGAACTTATAATATGAGAGGGGAGGATATTGTCATCCCAGGGGT
GGCTACTGTTGTAGAACGTTTATTAAATAATGGTAAGGCTCTGAGTAACAGACAAGCCCAAAATGATCCG
ATGCCACCCTTTAATATTACACAGAAAGTATCTGAGGATAGTAATGACTTTTCATTTAGTTCAGTTACCA
ATAGTTCTATATTAGAGGATGTATCACTTATTGCATATCCAGAAACCAATTCTATATTAGTCAAAGGTAA
TGATCAGCAAATACAGATTATTCGCGATATTATCACTCAGTTAGATGTAGCCAAACGACATATAGAATTA
TCATTATGGATAATCGATATTGATAAATCTGAATTAAATAACCTTGGTGTTAATTGGCAAGGAACGGCTT
CATTTGGTGATTCGTTTGGTGCGTCATTTAATATGAGCTCATCAGCATCGATAAGCACTTTGGACGGCAA
TAAGTTTATTGCTTCAGTTATGGCATTAAATCAGAAAAAGAAAGCAAATGTAGTTTCAAGGCCGGTGATT
TTGACACAAGAGAATATTCCGGCTATATTTGATAATAACAGGACTTTTTATGTGTCATTAGTTGGTGAGC
GCAATTCTTCGTTGGAGCATGTTACGTATGGAACATTGATAAATGTTATACCTCGCTTTTCATCTCGGGG
ACAAATTGAGATGTCTTTAACGATAGAGGATGGAACAGGAAATAGTCAGTCAAATTACAATTATAATAAT
GAAAATACATCTGTCCTTCCAGAAGTTGGAAGGACCAAAATCAGTACAATAGCGAGAGTTCCACAAGGCA
AAAGTTTGTTGATAGGTGGTTATACGCATGAAACGAACTCTAACGAAATAATATCCATTCCTTTTCTCTC
CTCTATTCCTGTAATCGGTAATGTGTTCAAGTATAAAACAAGTAATATCAGTAATATTGTAAGGGTTTTT
CTGATTCAACCCCGTGAGATAAAGGAGTCAAGTTATTATAATACTGCAGAATATAAAAGCCTCATATCTG
AAAGAGAAATACAAAAGACTACACAAATAATCCCATCTGAAACTACTTTGCTGGAAGACGAAAAATCATT
GGTTTCATACTTAAATTACTA
Protein Sequence 
>gi|13449092|ref|NP_085308.1| Type III secretion protein [Shigella flexneri 5a str. M90T] MKKFNIKSLTLLIVLLPLIVNANNIDSHLLEQNDIAKYVAQSDTVGSFFERFSALLNYPIVVSKQAAKKRISGEFDLSNPEEMLEKLTLLVGLIWYKDGNALYIYDSGELISKVILLENISLNYLIQYLKDANLYDHRYPIRGNISDKTFYISGPPALVELVANTATLLDKQVSSIGTDKVNFGVIKLKNTFVSDRTYNMRGEDIVIPGVATVVERLLNNGKALSNRQAQNDPMPPFNITQKVSEDSNDFSFSSVTNSSILEDVSLIAYPETNSILVKGNDQQIQIIRDIITQLDVAKRHIELSLWIIDIDKSELNNLGVNWQGTASFGDSFGASFNMSSSASISTLDGNKFIASVMALNQKKKANVVSRPVILTQENIPAIFDNNRTFYVSLVGERNSSLEHVTYGTLINVIPRFSSRGQIEMSLTIEDGTGNSQSNYNYNNENTSVLPEVGRTKISTIARVPQGKSLLIGGYTHETNSNEIISIPFLSSIPVIGNVFKYKTSNISNIVRVFLIQPREIKESSYYNTAEYKSLISEREIQKTTQIIPSETTLLEDEKSLVSYLNY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiD mutant is unable to invade HeLa cells or to provoke keratoconjunctivitis in guinea-pigs (Allaoui et al., 1993).
References
Allaoui et al., 1993: Allaoui A, Sansonetti PJ, Parsot C. MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins. Molecular microbiology. 1993; 7(1); 59-68. [PubMed: 8437520].