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trpB

Victor ID 4297
Gene Name trpB
Sequence Strain (Species/Organism) Staphylococcus aureus subsp. aureus N315
NCBI Gene ID 1124043
NCBI Protein GI 15926952
Locus Tag SA1204
Protein Accession NP_374485.1
Other Database IDs UniProtKB-ID: TRPB_STAAN
UniRef100: UniRef100_A7X238
UniRef90: UniRef90_A7X238
UniRef50: UniRef50_B1XY48
UniParc: UPI000013752B
EMBL: BA000018
EMBL-CDS: BAB42464.1
RefSeq_NT: NC_002745.2
EnsemblGenome: EBSTAG00000000414
EnsemblGenome_TRS: EBSTAT00000000414
EnsemblGenome_PRO: EBSTAP00000000414
GenomeReviews: BA000018_GR
KEGG: sau:SA1204
eggNOG: COG0133
HOGENOM: HBG303148
OMA: LKREDLC
ProtClustDB: PRK04346
BioCyc: SAUR158879:SA1204-MONOMER
Taxonomy ID 158879
Gene Starting Position 1376946
Gene Ending Position 1378160
Gene Strand (Orientation) +
Protein Name tryptophan synthase subunit beta
DNA Sequence 
>gi|29165615:1376946-1378160 Staphylococcus aureus subsp. aureus N315, complete genome
AATGAATAAACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTT
CCAGAAACATTAATGCCAGCAATTATTGAGTTGAAAAAAGCTTATAAAGAGGCAAAAGCAGACCCAGAGT
TTCAAAGAGAACTGGAATACTATTTATCAGAGTATGTAGGACGCGCGACACCACTTACATATGCTGCATC
ATATACTGAAAGCCTAGGTGGCGCTAAAATATATTTGAAACGAGAGGATCTAAATCATACAGGCGCCCAT
AAAATTAATAATGCGTTAGGTCAAGCGTTGCTTGCTAAAAGAATGGGCAAGAAGAAGCTTGTTGCTGAAA
CTGGTGCGGGTCAACATGGTGTAGCTAGTGCTACGGTTGCTGCATTATTTGATATGGAACTTGTTGTCTT
TATGGGAAGTGAAGATATTAAAAGACAACAACTTAATGTATTTAGAATGGAATTACTTGGTGCAAAGGTT
GTGGCAGTTGAAGAAGGTCAAGGGACTTTATCGGATGCAGTTAATAAAGCATTGCAATATTGGGTAAGTC
ATGTAGATGATACACATTATTTATTAGGTTCTGCATTAGGTCCAGACCCATTCCCAACGATTGTTAGAGA
TTTTCAGAGTGTCATTGGTAAAGAAATAAAATCACAGATATTGAAGAAAGAAGGTCGACTTCCGGATGCA
ATTGTAGCATGTATCGGTGGTGGCTCAAATGCAATCGGTACATTTTATCCATTTATTAAAGATGATGTTG
CATTATACGGTGTTGAAGCCGCAGGTCAAGGCGAGGATACTGATAAACATGCACTTGCAATTGGCAAAGG
ATCACCTGGCGTATTACATGGTACTAAAATGTATTTAATTCAAGATGAAGGTGGGCAAGTGCAACTAGCA
CATTCTATTTCAGCAGGACTTGATTATCCTGGTATTGGGCCTGAACATTCTTATTACCACGACATTGGTA
GAGTAACTTTTGAAAATGCAAGTGATACACAAGCAATGAATGCTTTAATCAACTTTACAAAACATGAAGG
TATTATACCTGCAATTGAAAGTGCACATGCACTGAGTTATGTTGAAAGACTAGCGCCTACGATGTCGAAA
GAAGATATTATTGTAGTAACTATTTCTGGACGTGGCGATAAAGATATGGAAACAATTAGACAATATATGG
CAGAGCGAGGTCTTGCAAATGACTA
Protein Sequence 
>gi|15926952|ref|NP_374485.1| tryptophan synthase subunit beta [Staphylococcus aureus subsp. aureus N315] MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in murine model (Mei et al., 1997).
COG COG0133E, under E: Amino acid transport and metabolism
References
Mei et al., 1997: Mei JM, Nourbakhsh F, Ford CW, Holden DW. Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis. Molecular microbiology. 1997; 26(2); 399-407. [PubMed: 9383163].