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thrB

Victor ID 4292
Gene Name thrB
Sequence Strain (Species/Organism) Staphylococcus aureus subsp. aureus N315
NCBI Gene ID 1124002
NCBI Protein GI 15926911
Locus Tag SA1166
Protein Accession NP_374444.1
Other Database IDs UniProtKB-ID: KHSE_STAAN
UniRef100: UniRef100_A7X1Y2
UniRef90: UniRef90_A7X1Y2
UniRef50: UniRef50_Q2FYV2
UniParc: UPI000012DE32
EMBL: BA000018
EMBL-CDS: BAB42423.1
RefSeq_NT: NC_002745.2
EnsemblGenome: EBSTAG00000002108
EnsemblGenome_TRS: EBSTAT00000002108
EnsemblGenome_PRO: EBSTAP00000002108
GenomeReviews: BA000018_GR
KEGG: sau:SA1166
eggNOG: COG0083
HOGENOM: HBG646290
OMA: FDCLGAA
ProtClustDB: PRK01212
BioCyc: SAUR158879:SA1166-MONOMER
Taxonomy ID 158879
Gene Starting Position 1327840
Gene Ending Position 1328754
Gene Strand (Orientation) +
Protein Name homoserine kinase homolog
DNA Sequence 
>gi|29165615:1327840-1328754 Staphylococcus aureus subsp. aureus N315, complete genome
CATGTCGAATGTTTTGGAGTTAACAATTCCTGCATCAACAGCCAACCTTGGAGTTGGCTTTGATTCTATA
GGTATGGCTTTAGATAAATTTTTGCATCTGTCTGTAAAGGAAACATCAGGGACAAAATGGGAATATATTT
TCCATGATGATGCATCTAAGCAATTGCCTACTGACGAAACAAACTTTATTTATCATGTAGCACAACAAGT
TGCTTCTAAATATAGTGTTGACTTGCCTATTTTATGTATCGAAATGAGAAGTGATATTCCATTGGCAAGA
GGGTTAGGTTCGTCAGCTTCTGCTTTAGTAGGAGCTATATATATCGCAAATTATTTTGGTGATATCCAAC
TGTCTAAACATGAGGTATTACAATTAGCGACTGAAATCGAAGGACATCCTGATAATGTTGCGCCGACCAT
TTATGGTGGTTTAATCGCTGGATTTTATAATGATGTCTCGAAAGAAACGTCAGTTGCACATATCGACATA
CCAGACGTGGATGTGATTGTAACGATACCAACTTATGAACTAAAAACAGAAGCATCAAGACGTGCTTTAC
CACAAAAATTAACACATAGTGAAGCGGTAAAAAGTAGTGCAATTAGTAATACAATGATTTGTGCATTAGC
ACAGCACAATTATGAATTAGCAGGTAAACTCATGCAACAAGATGGCTTTCATGAACCGTATCGTCAGCAT
TTAATTGCTGAATTTGATGAAGTGAAAACAATTGCTAGTCAACATAATGCCTATGCAACTGTAATTAGTG
GTGCTGGACCAACTATTTTAATATTTAGTCGTAAAGAAAATAGTGGGGAATTGGTTCGCTCTTTAAATAG
TCAGGTAGTATCATGCCATTCTGAATTGGTCGATATTAATATCAGTGGTGTTAAAGAACGAATTGTATAC
CAATA
Protein Sequence 
>gi|15926911|ref|NP_374444.1| homoserine kinase [Staphylococcus aureus subsp. aureus N315] MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPILCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGFYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in murine model (Mei et al., 1997).
COG COG0083E, under E: Amino acid transport and metabolism
References
Mei et al., 1997: Mei JM, Nourbakhsh F, Ford CW, Holden DW. Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis. Molecular microbiology. 1997; 26(2); 399-407. [PubMed: 9383163].