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purL

Victor ID 4288
Gene Name purL
Sequence Strain (Species/Organism) Staphylococcus aureus subsp. aureus N315
NCBI Gene ID 1123744
NCBI Protein GI 15926655
Locus Tag SA0921
Protein Accession NP_374188.1
Other Database IDs UniProtKB-ID: PURL_STAAN
UniRef100: UniRef100_A7X0W1
UniRef90: UniRef90_A7X0W1
UniRef50: UniRef50_A7X0W1
UniParc: UPI0000132B41
EMBL: BA000018
EMBL-CDS: BAB42166.1
RefSeq_NT: NC_002745.2
EnsemblGenome: EBSTAG00000002331
EnsemblGenome_TRS: EBSTAT00000002331
EnsemblGenome_PRO: EBSTAP00000002331
GenomeReviews: BA000018_GR
KEGG: sau:SA0921
eggNOG: COG0046
HOGENOM: HBG311214
OMA: YGNSFGV
ProtClustDB: PRK01213
BioCyc: SAUR158879:SA0921-MONOMER
Taxonomy ID 158879
Gene Starting Position 1044833
Gene Ending Position 1047022
Gene Strand (Orientation) +
Protein Name phosphoribosylformylglycinamidine synthase II
DNA Sequence 
>gi|29165615:1044833-1047022 Staphylococcus aureus subsp. aureus N315, complete genome
CATGTCTAAATTTATCGAACCAAGCGTTGAAGAAATTAAACTTGAAAAAGTATATCAAGATATGGGATTA
AGTGATCAAGAATATGAAAAAGTTTGCGATATTTTAGGCAGACAACCTAACTTTACAGAAACAGGTATCT
TTTCTGTTATGTGGAGTGAACATTGCTCTTATAAACATTCTAAACCGTTTTTAAAGCAATTTCCTACGTC
AGGTGAGCATGTGCTTATGGGTCCAGGTGAAGGTGCAGGGGTAGTCGATATAGGTGATAATCAAGCCGTA
GTATTTAAAGTAGAGTCTCACAATCATCCATCAGCAATTGAACCATATCAAGGGGCTGCTACAGGCGTTG
GTGGAATCATTCGTGACATTGTTTCTATTGGGGCTAGACCTATTAATTTGTTAAACAGTCTTAGATTTGG
AGAATTAGATAATAAACAAAACCAAAGATTACTTAAAGGGGTTGTAAAGGGTATCGGAGGTTATGGTAAC
TGCATTGGTATTCCAACAACTGCTGGTGAAATCGAATTTGATGAACGTTATGATGGCAATCCACTTGTTA
ATGCAATGTGTGTTGGTGTTATCAATCACGACATGATTCAAAAAGGCACAGCAAAAGGTGTAGGTAATTC
GGTCATTTATGTTGGTTTGAAAACTGGTCGAGATGGTATTCATGGTGCTACTTTTGCATCTGAAGAATTG
ACGGAAGAAAGCGAAAGTAAACGACCTTCTGTACAAATCGGTGATCCATTTGTAGGTAAAAAATTAATGG
AAGCAACACTTGAAGCAATTACATTTGATGAATTAGTTGGTATTCAAGATATGGGTGCTGCTGGTTTAAC
ATCTTCATCGTCTGAAATGGCGGCAAAAGGTGGTAGTGGGTTACATTTGAGATTAGAACAAGTGCCAACA
CGTGAGCCAGGTATTTCTCCTTATGAAATGATGCTTTCAGAAACTCAAGAACGTATGTTACTAGTTGTTG
AAAAAGGTAATGAACAAAAATTCTTAGATTTATTTGATAAGCACGAATTGGATAGTGCTGTTATAGGTGA
AGTTACAGATACAAATCGTTTTGTTTTAACATATGATGATGAAGTTTATGCTGACATTCCAGTTGAACCA
CTAGCTGATGAAGCACCTGTATATATTTTAGAAGGAGAAGAAAAAGATTATAATACTTCTAAAAATGATT
ATACACACATCGATGTTAAAGATACTTTCTTTAAATTACTTAAGCATCCGACTATAGCATCTAAACACTA
TTTATATGATCAATACGACCAACAAGTTGGTGCCAATACGATAATTAAGCCAGGACTTCAAGCATCGGTA
GTACGTGTGGAAGGCACAAATAAGGCAATTGCTTCAACAATTGATGGTGAAGCGCGTTATGTATATAACA
ATCCATATGAAGGTGGAAAGATGGTAGTAGCTGAAGCTTATCGAAATTTAATTGCCGTGGGTGCAACACC
ATTAGCAATGACAGATTGTTTAAATTATGGTTCTCCTGAAAAGAAAGAAATCTATCAACAGTTGATAGAT
TCAACGAAAGGTATGGCAGAAGCATGCGACATTCTTAAGACACCAGTAGTTTCTGGAAATGTATCTTTAT
ATAACGAAACGAAAGGTACTTCTATTTTCCCAACACCAGTTGTTGGAATGGTAGGTTTGATTGAAAATGT
AAATTATTTAAATGATTTTGAACCTCAAGTTGGAGATAAATTATATTTAATCGGTGATACTAAGGACGAC
TTTGGTGGTAGTCAACTTGAAAAGTTAATTTATGGCAAAGTTAATCATGAATTTGAGTCATTAGATTTGA
GTTCAGAAGTTGAAAAAGGTGAATCAATCAAGACCGCTATTCGTGAAGGACTATTATCACATGTTCAAAC
AGTTGGTAAAGGTGGCTTACTGATTACCTTAGCTAAACTAAGTGCGCATTACGGTTTAGGATTAAAATCT
TCAATAGATATAACAAATGCACAATTGTTTAGTGAGACACAAGGCCGATATGTTGTTTCTGTTAAATCAG
GTAAAACTTTAAATATTGATAATGCAATAGAAATTGGACTTTTAACAGATAGTGATAATTTCAAAGTAAC
AACACCATATACAGAGATTAGTGAAAATGTTTCAGATATTAAACAAATATGGGAAGGGGCAATTGCTCAA
TGTTTAACTACTCAGGATTA
Protein Sequence 
>gi|15926655|ref|NP_374188.1| phosphoribosylformylglycinamidine synthase II [Staphylococcus aureus subsp. aureus N315] MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in murine model (Mei et al., 1997).
COG COG0046F, under F: Nucleotide transport and metabolism
References
Mei et al., 1997: Mei JM, Nourbakhsh F, Ford CW, Holden DW. Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis. Molecular microbiology. 1997; 26(2); 399-407. [PubMed: 9383163].