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SPy_1633

Victor ID 4283
Gene Name SPy_1633
Sequence Strain (Species/Organism) Streptococcus pyogenes M1 GAS
NCBI Gene ID 901885
NCBI Protein GI 15675508
Locus Tag SPy_1633
Genbank Accession AE004092
Protein Accession NP_269682
Other Database IDs UniProtKB-ID: CNPD_STRP1
UniRef100: UniRef100_Q1JAJ3
UniRef90: UniRef90_Q1JAJ3
UniRef50: UniRef50_A3CPX8
UniParc: UPI000000AC43
EMBL: AE004092
EMBL: CP000017
EMBL-CDS: AAK34403.1
EMBL-CDS: AAZ51960.1
RefSeq_NT: NC_002737.1
RefSeq_NT: NC_007297.1
EnsemblGenome: EBSTRG00000000794
EnsemblGenome_TRS: EBSTRT00000000794
EnsemblGenome_PRO: EBSTRP00000000794
EnsemblGenome: EBSTRG00000028693
EnsemblGenome_TRS: EBSTRT00000028693
EnsemblGenome_PRO: EBSTRP00000027711
GenomeReviews: AE004092_GR
GenomeReviews
Taxonomy ID 160490
Gene Starting Position 1354207
Gene Ending Position 1355814
Gene Strand (Orientation) -
Protein Name hypothetical protein
Protein pI 5.62
Protein Weight 56808.67
Protein Length 535
Protein Note Best Blastp hit = gb|AAF34762.1|AF228345_1 (AF228345) unknown [Listeria monocytogenes]
DNA Sequence 
>gi|15674250:1354207-1355814 Streptococcus pyogenes M1 GAS chromosome, complete genome
TCTACTTGGCATAATCAACCGCTCTCATCTCACGAATAACAGTTACTTTAATATTTCCTGGGTAATCTAG
ATTGTTTTCAATTTTTTCTCTTACTTTATGCGACAAAATGACAACCTGATCATCTGAAATTTTTTCAGGT
TGAACCATAATACGAATCTCACGTCCAGCTTGTAGAGCAAAACTATTTTGTACCCCATCAAAACTTGTCG
CGATTTCTTCTAAATCACGAAGACGCTTGATGTAATTCTCCATTGACTCATTACGAGCGCCTGGACGAGC
CGAACTGAGAGCGTCTGCTGCAGCTACTAGCACAGCGATCACAGAATCTGGCTCCACATCTCCGTGGTGG
CTAGCAATAGTGTTGACAACAACTGGATGTTCTTTGTATTTACGTGCAAATTCCATTCCAATCTCAACGT
GACTGCCTTCAACCTCACGGTCAATAGCTTTACCCATATCATGCAAGAAACCAGCACGGCGGGCAAGAGC
AACATTTTCACCTAACTCACCAGCTAAAATACCAGCTAACTTACCAACCTCAACAGAGTGACGTAGGACA
TTTTGACCAAACGAGGTACGGAATTGCAGGCGTCCCATGATTTTAATCAAATCAGGATGAAGGTTTGGTG
CACCAATCTCATAGGCTGCAGCTTCACCGTACTCACGAATACGATTATCCATTTCAAGACGATTTTTCTC
AACCAATTCCTCGATACGAGCTGGATGGATGCGACCATCAGCAATCAGAGATTCCAAGGTCATACGAGCA
ATTTCACGTCGAATAGGATCAAATCCTGATAAGATAACAACTTCAGGAGTATCGTCAATAATAACGTCAA
TGCCAGTCAAGCTCTCTAAAGTACGAATATTACGGCCTTCACGTCCAATAATTCGGCCCTTCATGTTGTC
GTCTGGGAGATGGACACTGGTAATAGTTTGTTCAGTCACATACTCACCAGCAAGGCGTTGCATGGCTTGC
GCTAACAAGTCCTTGGCTGTTTTAACTGTTCGGTCCTTGATGTCACGTTCGGCATCTCGAATGCGCGTCG
CAATTTCATGGGTCAGTTTGTTTTCCGTCTCCATTAAAATCACTTCACGCGCTTCTGCAATCGTCATCGC
AGCAACTTTTTCCAGTTCTGCTTTTTTCTCCTCTTCAAGTTTTTCCACTTGAAGTTGCCGCTCATCAATG
TGTTTAGATTTATCGGTCAGACTTTGTTCTTTACTATCTAGTACCTTTTCTTTACTTGATAGGTTTTCAT
CTTTACGGTCAAGAGTTAAGGAGCGCTCCGCTAAGCGTGTCTCGAGTTGTTTAAGCTCTTGTCTTTCAGA
CTTAAATTCTTGTTCAATCTCTTCACGATATTTTCTTGCCTCTTCTTTTGCTTCTAAAAGTAATTCTTTA
CGATTTGCTTTACTTTCACGTTTAGCTGTTTTTTTGATGTGTTCAGCATCTACTTCTGCTTTGCCACGAA
TATCAACAGCTTCTTGTTCAGCGTTTAAAAGAGTCAACTCTGCAGCTTCCTTCGCAGACTTGAGTCTAAT
CGAAATAAGTGCATAACCTAATATTAAACCAATGAGGGCAGAAACAATTAATAAAATAATATTAACCA
Protein Sequence 
>gi|15675508|ref|NP_269682.1| hypothetical protein SPy_1633 [Streptococcus pyogenes M1 GAS]
MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGKAEVDAEHIKKTAKRESKANR
KELLLEAKEEARKYREEIEQEFKSERQELKQLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKH
IDERQLQVEKLEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLA
QAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPIRREI
ARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQN
VLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEIGMEFARKYKEHPVVVNTIAS
HHGDVEPDSVIAVLVAAADALSSARPGARNESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQ
PEKISDDQVVILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SPy_1633 (cvfA) mutant is attenuated in mice (Kang et al., 2010).
COG COG1418R, under R: General function prediction only
References
Kang et al., 2010: Kang SO, Caparon MG, Cho KH. Virulence gene regulation by CvfA, a putative RNase: the CvfA-enolase complex in Streptococcus pyogenes links nutritional stress, growth-phase control, and virulence gene expression. Infection and immunity. 2010; 78(6); 2754-2767. [PubMed: 20385762].