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mxiJ from Shigella flexneri 5a

Victor ID 42
Gene Name mxiJ from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876511
NCBI Protein GI 13449086
Locus Tag pWR501_p147
Protein Accession NP_085302.1
Other Database IDs UniProtKB-ID: MXIJ_SHIFL
UniRef100: UniRef100_Q06081
UniRef90: UniRef90_Q06081
UniRef50: UniRef50_Q06081
UniParc: UPI000012FAB2
EMBL: M98390
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: AAA26532.1
EMBL-CDS: CAC05814.1
EMBL-CDS: AAK18458.1
EMBL-CDS: AAL72328.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093164
EnsemblGenome_TRS: EBESCT00000094120
EnsemblGenome_PRO: EBESCP00000090327
GenomeReviews: AF386526_GR
KEGG: sfl:CP0139
HOGENOM: HBG671305
OMA: HISVIAI
P
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 113527
Gene Ending Position 114252
Gene Strand (Orientation) +
Protein Name Type III secretion protein
DNA Sequence 
>gi|13448939:113527-114252 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TATGATTAGGTATAAAGGTTTTATTTTATTCTTGTTGCTGATGTTGATTGGATGTGAGCAACGTGAAGAG
TTAATTTCTAATTTATCTCAAAGACAGGCAAATGAAATAATATCTGTGCTAGAACGCCATAATATTACTG
CTAGAAAAGTTGATGGAGGTAAACAGGGGATCTCGGTACAAGTCGAAAAGGGGACATTTGCATCGGCAGT
TGATTTGATGCGCATGTACGATTTGCCAAATCCGGAGAGAGTTGATATCTCACAAATGTTTCCTACAGAT
TCATTAGTGTCTTCTCCAAGAGCTGAAAAGGCCCGTTTATATAGTGCTATTGAGCAACGGCTGGAACAGT
CTTTAGTTTCTATTGGTGGTGTTATTTCGGCAAAAATACATGTTAGCTATGATCTTGAAGAAAAAAATAT
ATCTTCAAAACCGATGCATATATCAGTAATCGCTATATATGACTCACCGAAAGAGTCTGAACTATTAGTT
AGTAATATTAAGCGATTTTTGAAAAACACCTTTTCTGATGTTAAGTATGAAAATATATCTGTCATATTAA
CTCCGAAAGAAGAATATGTTTATACAAATGTACAACCTGTTAAGGAAGTTAAATCGGAATTTTTAACAAA
TGAAGTAATATATTTATTTCTCGGGATGGCTGTACTAGTTGTCATTCTTTTGGTATGGGCATTCAAAACA
GGGTGGTTCAAGAGAAACAAAATATG
Protein Sequence 
>gi|13449086|ref|NP_085302.1| Type III secretion protein [Shigella flexneri 5a str. M90T] MIRYKGFILFLLLMLIGCEQREELISNLSQRQANEIISVLERHNITARKVDGGKQGISVQVEKGTFASAVDLMRMYDLPNPERVDISQMFPTDSLVSSPRAEKARLYSAIEQRLEQSLVSIGGVISAKIHVSYDLEEKNISSKPMHISVIAIYDSPKESELLVSNIKRFLKNTFSDVKYENISVILTPKEEYVYTNVQPVKEVKSEFLTNEVIYLFLGMAVLVVILLVWAFKTGWFKRNKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiJ mutant was unable to invade HeLa cells, to induce the formation of plaques on confluent monolayers of HeLa cells, and to provoke keratoconjunctivitis in guinea pigs (Allaoui et al., 1992).
References
Allaoui et al., 1992: Allaoui A, Sansonetti PJ, Parsot C. MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. Journal of bacteriology. 1992; 174(23); 7661-7669. [PubMed: 1332940].