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vicK

Victor ID 4183
Gene Name vicK
Sequence Strain (Species/Organism) Streptococcus equi
NCBI Gene ID 6760966
NCBI Protein GI 195978500
Locus Tag Sez_1395
Protein Accession YP_002123744.1
Other Database IDs UniProtKB-ID: B4U414_STREM
UniRef100: UniRef100_B4U414
UniRef90: UniRef90_B5XKB5
UniRef50: UniRef50_B5XKB5
UniParc: UPI00017BD5DE
EMBL: CP001129
EMBL-CDS: ACG62731.1
RefSeq_NT: NC_011134.1
EnsemblGenome: EBSTRG00000008584.
EnsemblGenome_TRS: EBSTRT00000008584
EnsemblGenome_PRO: EBSTRP00000008145
GenomeReviews: CP001129_GR
KEGG: sez:Sez_1395
HOGENOM: HBG334875
OMA: THENLIQ
ProtClustDB: CLSK876742
Taxonomy ID 552526
Gene Starting Position 1433586
Gene Ending Position 1434938
Gene Strand (Orientation) -
Protein Name TCS sensor kinase VicK
DNA Sequence 
>gi|195977156:1433586-1434938 Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome
ATTAATCAATATCATCCTCCCATTCATCATAGATAGCAGCATCCTTTTCATAAGGTAACACAATGGTAAA
GGTTGAGCCCTTGCCATAATCACTCTTAGCCCAAATAAAGCCTCGGTGCTGCTTAATAATTTCTTTAGCA
ATCGCTAGGCCTAGCCCGGTCCCTCCTTGAGCTCTACTCCTAGCCTTATCCACTCGGTAAAAACGGTCAA
AAATCAAAGGCAGGTCCTTTTTTGGAATACCCAAGCCCTCATCAGAAATCGAAATGATTAGCTGGGTATC
TGTTGTTTTCATGTTGACGACAATTTTTCCGCCATCGGGTGAATATTTGATCGCATTGTTTAAAATATTT
TCGATAACCTGCGTCATTTTGTCATCGTCAATTTCTAGCCAAATAGAGGTAATGGGGTAATCTCTGACAA
TTTCATAGGATTTTCCTGTGCTTGTGTGCTGATTTTTCACCAAATCAAAGCGGTTTAAGATAGAGGTCAT
AAAGGCTGTAAAGTTGGTCATTTCAACAGACAGCTGTGTCACATGATTATCAATTCTTGAGAGGTTGAGC
AAATCTGAAATCATGCGCATCATGCGATTGGTTTCATCTAGTGAGACCTTTATAAAGCTTGGAGCGATGT
CCTCCTTTAGCGCGCCCTCATCTAGAGCCTCTAGGTATGACTTGACAGAGGTCAAAGGTGTCCGCAGCTC
ATGGCTAACATTTGAAACAAAGAGTCTGCGCTCGCGCTCTTCCTTTTCCTGCTCAGTCGTGTCATGAAGT
ACAACAACCAGACCTGAAATAAAGCCGCTCTCTCGCCTATTAAGCGCAAAGCGCAGCCGCAGGGAAACAA
ATTCTCCTGTATCATTACGACGGTTTAAGGTCACAATCGGTGTTTTTGAGACCAGCTCTCGGTAGGTATA
AGGGGAGTCACTGTCTAATAAATCTGTAATGTTTTTTTCCAAGGCCTGCTCGCGATTTAAATTGAGCTGC
TTTTGAGCAGTCTCATTAATCATGATAATCTTGCCGGAACGATTGGTCGCAAGGACCCCATCTGTCATAT
AAGCCAAAATACTAGCAAGACGATTTTTTTCTTGAGCAAGGTTTTCATGAGTCAGACGAAAAACATCTGA
TAGGTCATTGAGCTGCTCAGACAGCTCCATCAATTCAATATCAGCCTTTTCATTGATCGTATCAGTATAG
CGACCATTGATCAAATCTCTTATCTTGTGGCTCATCAGACGAATGATCCGAGCATTGCGATAATCACGAA
TGGCTAAATGAATGAAATAAAAAGCAACAAAAACAAGCAATAAGAGTATGGCTAGCTCAAATGCAGAAAG
GTTTCCAATGATGTCCTTAGTCA
Protein Sequence 
>gi|195978500|ref|YP_002123744.1| TCS sensor kinase VicK [Streptococcus equi subsp. zooepidemicus MGCS10565] MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPIVTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDDDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: vicK mutant was attenuated in mice (Liu et al., 2008).
COG COG5002T, under T: Signal transduction mechanisms
References
Liu et al., 2008: Liu M, McClure MJ, Zhu H, Xie G, Lei B. The Two-Component Regulatory System VicRK is Important to Virulence of Streptococcus equi Subspecies equi. The open microbiology journal. 2008; 2; 89-93. [PubMed: 19088917].