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YPTS_4218

Victor ID 4161
Gene Name YPTS_4218
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis PB1/+
NCBI Gene ID 6261827
NCBI Protein GI 186897507
Locus Tag YPTS_4218
Genbank Accession CP001049
Protein Accession YP_001874618
Other Database IDs UniProtKB-ID: B2KAE7_YERPB
UniRef100: UniRef100_P69978
UniRef90: UniRef90_P69978
UniRef50: UniRef50_P69978
UniParc: UPI000013C097
EMBL: CP001049
EMBL-CDS: ACC91161.1
RefSeq_NT: NC_010635.1
GenomeReviews: CP001049_GR
KEGG: ypb:YPTS_4218
HOGENOM: HBG273653
ProtClustDB: CLSK862150
Taxonomy ID 502801
Plasmid No pYPTS01
Gene Starting Position 7807
Gene Ending Position 8154
Gene Strand (Orientation) +
Protein Name protein-tyrosine phosphatase YopH
Protein pI 6.51
Protein Weight 11816.44
Protein Length 115
Protein Note PFAM: Protein-tyrosine phosphatase YopH~KEGG: yps:pYV0089 YscM, LcrQ; putative type III secretion regulatory
DNA Sequence 
>gi|186897495:7807-8154 Yersinia pseudotuberculosis PB1/+ plasmid pYPTS01, complete sequence
GATGAAAATCAATACTCTTCAATCGTTAATAAATCAACAAATTACCCAAGTGGGACACGGGGGGCAGGCC
GGTCGTCTCACTGAAACTAACCCACTCACAGAGAATAGTCATCAGATATCTACCGCCGAAAAAGCCTTTG
CCAATGAGGTGCTGGAACATGTGAAAAATACGGCTCTCAGTCGTCACGATATTGCCTGCTTATTACCACG
CGTTTCTAATTTGGAACTAAAGCAGGGCAAGGCAGGGGAAGTGATAGTGACCGGCTTGCGTACTGAACAA
CTCTCGCTTAGCGATGCTAAATTATTGCTAGAAGCCGCCATGCGCCAGGATACGGCGGCTGACGGCTG
Protein Sequence 
>gi|186897507|ref|YP_001874618.1| protein-tyrosine phosphatase YopH [Yersinia pseudotuberculosis PB1/+]
MKINTLQSLINQQITQVGHGGQAGRLTETNPLTENSHQISTAEKAFANEVLEHVKNTALSRHDIACLLPR
VSNLELKQGKAGEVIVTGLRTEQLSLSDAKLLLEAAMRQDTAADG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopH mutant is attenuated in mice (Deleuil et al., 2003).
References
Deleuil et al., 2003: Deleuil F, Mogemark L, Francis MS, Wolf-Watz H, Fällman M. Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism. Cellular microbiology. 2003; 5(1); 53-64. [PubMed: 12542470].