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cls from Yersinia pseudotuberculosis PB1/+

Victor ID 4157
Gene Name cls from Yersinia pseudotuberculosis PB1/+
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis PB1/+
NCBI Gene ID 6259537
NCBI Protein GI 186895486
Locus Tag YPTS_2180
Protein Accession YP_001872598.1
Other Database IDs UniProtKB-ID: CLS_YERPB
UniRef100: UniRef100_B2K3U5
UniRef90: UniRef90_A1JQ40
UniRef50: UniRef50_Q8D2I8
UniParc: UPI0000426BD8
EMBL: CP001048
EMBL-CDS: ACC89141.1
RefSeq_NT: NC_010634.1
GenomeReviews: CP001048_GR
KEGG: ypb:YPTS_2180
HOGENOM: HBG694312
OMA: SKKVKMA
ProtClustDB: PRK01642
Taxonomy ID 502801
Gene Starting Position 2406767
Gene Ending Position 2408227
Gene Strand (Orientation) -
Protein Name cardiolipin synthetase
DNA Sequence 
>gi|186893344:2406767-2408227 Yersinia pseudotuberculosis PB1/+ chromosome, complete genome
TTTACAGTAATGGGCTGAAAAAATAGAATAAACGCTCAGTTACTCTGTGCCAAAGAGGGCGCTTGTTCCA
CCGTTCACCATCCAATAAGGCAGAGCGGGCGATATAATCATCCTGAACTTGTGCTAAATCAGCCCCAAAG
CCATCATCATCAATCACCAGTGTGATTTCAAAATTCAGCCACAAACTGCGCATATCCAGATTAACAGTGC
CGACTAAACTTAGCTGTCCATCGACCAGAACACTTTTACTGTGTAATAGGCCGCCTTCAAACTGATAAAT
TTTAACGCCTGCATTCAGCAATTCGGTGAAGAATGCTCGGCTGGCCCAGCGAACCATCATCGAATCATTC
TCACGCGGGACAATAATACTGACATCAACCCCGCGTTGTGCCGCGGTACAGATGGCATGTAATAAGTCAT
CACTGGGGACAAAATATGGCGTAGTCATAATTAACTGTTCACGTGCGGCATACACAGCTGTTAATAATGC
CTGGTGGATCATTTCTTCTGGGAAACCAGGGCCAGAAGCGATGACTTGAATCGTATGACCAGTCTCTTCT
TCGAATGGCATAATATTCGCGTCGGGGGGCGGGGGTAAAATACGTTTGCCTGTTTCAATTTCCCAGTCAC
AGGCATAAACAATACCTAGGGTTGTGGCTACCGGGCCTTCCATGCGCGCCATCATATCAATCCACTGACC
AACCCCGGCATCTTGTTTGAAGAACCGGGGATCTACCATGTTCATACTGCCGGTATAAGCAACATAGTTG
TCGATTAACACAATTTTCCGATGTTGGCGCAGATCCATTCGGCGCAAGAACATACGAAATACATTAACTT
TAAGTGCCTCAACCACCTCAATACCTGCATTACGCATCATTGCGGGATAAGGGCTGCGGAAAAATTGCTT
GCTACCCGCTGAATCGAGTAACAGCCGGCAATGAACGCCGCGTCGAGCCGCAGCCATCAACGATTCAGCC
ACCTGATCGACCAGACCACCAGGTTGCCAAATATAAAACACCATTTCTATATTGTGGCGGGCGAGTTCAA
TATCTCGTACTAGCGCTTTTAGTGTGTCATCGGTTGTTGTTAATAGTTGTAGTTGATTTCCTTTAACACC
GTTTATTCCTTGACGCCGTTCGCATAATTGAAACAGTGGGGTGGCAACTTCGCTATTAGAGTTAGCAAAG
ATATGTTGGCATTCCTTGAGTTCACTCAGCCAGCGAGCGGTCGATGGCCACATGGCTTTAGCTCGTTCAG
CACGCCGCTTACCCAAATGCAATTCACCGAATGAAAGGTAAGCAATTATCCCCACCAATGGCAGAATGTA
GATAATCAGTAACCAAGCCATAGCAGAAGGAACGGCCCTGCGTTTCATCAGAATACGCAATGTTACCCCG
GCAATGAGTAACCAGTAGCCAAAAACGGAAAGCCAACTGATTACGGTATAAAATGTCGTCA
Protein Sequence 
>gi|186895486|ref|YP_001872598.1| cardiolipin synthetase [Yersinia pseudotuberculosis PB1/+] MTTFYTVISWLSVFGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERAKAMWPSTARWLSELKECQHIFANSNSEVATPLFQLCERRQGINGVKGNQLQLLTTTDDTLKALVRDIELARHNIEMVFYIWQPGGLVDQVAESLMAAARRGVHCRLLLDSAGSKQFFRSPYPAMMRNAGIEVVEALKVNVFRMFLRRMDLRQHRKIVLIDNYVAYTGSMNMVDPRFFKQDAGVGQWIDMMARMEGPVATTLGIVYACDWEIETGKRILPPPPDANIMPFEEETGHTIQVIASGPGFPEEMIHQALLTAVYAAREQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPRENDSMMVRWASRAFFTELLNAGVKIYQFEGGLLHSKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSALLDGERWNKRPLWHRVTERLFYFFSPLL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cls mutant is attenuated in mice (Mecsas et al., 2001).
COG COG1502I, under I: Lipid transport and metabolism
References
Mecsas et al., 2001: Mecsas J, Bilis I, Falkow S. Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis. Infection and immunity. 2001; 69(5); 2779-2787. [PubMed: 11292689].