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cls from Yersinia pseudotuberculosis YPIII

Victor ID 4153
Gene Name cls from Yersinia pseudotuberculosis YPIII
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis YPIII
NCBI Gene ID 6087380
NCBI Protein GI 170024298
Locus Tag YPK_2063
Protein Accession YP_001720803.1
Other Database IDs UniProtKB-ID: CLS_YERPY
UniRef100: UniRef100_B1JKT9
UniRef90: UniRef90_A1JQ40
UniRef50: UniRef50_Q8D2I8
UniParc: UPI00016DC16D
EMBL: CP000950
EMBL-CDS: ACA68350.1
RefSeq_NT: NC_010465.1
GenomeReviews: CP000950_GR
KEGG: ypy:YPK_2063
HOGENOM: HBG694312
OMA: SKKVKMA
ProtClustDB: PRK01642
Taxonomy ID 502800
Gene Starting Position 2290017
Gene Ending Position 2291477
Gene Strand (Orientation) +
Protein Name cardiolipin synthetase
DNA Sequence 
>gi|170022262:2290017-2291477 Yersinia pseudotuberculosis YPIII chromosome, complete genome
TATGACGACATTTTATACCGTAATCAGTTGGCTTTCCGTTTTTGGCTACTGGTTACTCATTGCCGGGGTA
ACATTGCGTATTCTGATGAAACGCAGGGCCGTTCCTTCTGCTATGGCTTGGTTACTGATTATCTACATTC
TGCCATTGGTGGGGATAATTGCTTACCTTTCATTCGGTGAATTGCATTTGGGTAAGCGGCGTGCTGAACG
AGCTAAAGCCATGTGGCCATCGACCGCTCGCTGGCTGAGTGAACTCAAGGAATGCCAACATATCTTTGCT
AACTCTAATAGCGAAGTTGCCAGCCCACTGTTTCAATTATGTGAACGGCGTCAAGGAATAAACGGTGTTA
AAGGAAATCAACTACAACTATTAACAACAACCGATGACACACTAAAAGCGCTAGTACGAGATATTGAACT
CGCCCGCCACAATATAGAAATGGTGTTTTATATTTGGCAACCTGGTGGTCTGGTCGATCAGGTGGCTGAA
TCGTTGATGGCTGCGGCTCGACGCGGCGTTCATTGCCGGCTGTTACTCGATTCAGCGGGTAGCAAGCAAT
TTTTCCGCAGCCCTTATCCCGCAATGATGCGTAATGCAGGTATTGAGGTGGTTGAGGCACTTAAAGTTAA
TGTATTTCGTATGTTCTTGCGCCGAATGGATCTGCGCCAACATCGGAAAATTGTGTTAATCGACAACTAT
GTTGCTTATACCGGCAGTATGAACATGGTAGATCCCCGGTTCTTCAAACAAGATGCCGGGGTTGGTCAGT
GGATTGATATGATGGCGCGCATGGAAGGCCCGGTAGCCACAACCCTAGGTATTGTTTATGCCTGTGACTG
GGAAATTGAAACAGGCAAACGTATTTTACCCCCGCCCCCCGACGCGAATATTATGCCATTCGAAGAAGAG
ACTGGTCATACGATTCAAGTCATCGCTTCTGGCCCTGGTTTCCCAGAAGAAATGATCCACCAGGCATTAT
TAACAGCTGTGTATGCCGCACGTGAACAGTTAATTATGACTACGCCATATTTTGTCCCCAGTGATGACTT
ATTACATGCCATCTGTACCGCGGCACAACGCGGGGTTGATGTCAGTATTATTGTCCCGCGTGAGAATGAT
TCGATGATGGTTCGCTGGGCCAGCCGAGCATTCTTCACCGAATTGCTGAATGCAGGCGTTAAAATTTATC
AGTTTGAAGGCGGCCTATTACACAGTAAAAGTGTTCTGGTCGATGGACAGCTAAGTTTAGTCGGCACTGT
TAATCTGGATATGCGCAGTTTGTGGCTGAATTTTGAAATCACACTGGTGATTGATGATGATGGCTTTGGG
GCTGATTTAGCACAAGTTCAGGATGATTATATCGCCCGCTCTGCCTTATTGGATGGTGAACTGTGGAACA
AGCGCCCTCTTTGGCACCGAGTAACTGAGCGTTTATTCTATTTTTTCAGCCCATTACTGTA
Protein Sequence 
>gi|170024298|ref|YP_001720803.1| cardiolipin synthetase [Yersinia pseudotuberculosis YPIII] MTTFYTVISWLSVFGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERAKAMWPSTARWLSELKECQHIFANSNSEVASPLFQLCERRQGINGVKGNQLQLLTTTDDTLKALVRDIELARHNIEMVFYIWQPGGLVDQVAESLMAAARRGVHCRLLLDSAGSKQFFRSPYPAMMRNAGIEVVEALKVNVFRMFLRRMDLRQHRKIVLIDNYVAYTGSMNMVDPRFFKQDAGVGQWIDMMARMEGPVATTLGIVYACDWEIETGKRILPPPPDANIMPFEEETGHTIQVIASGPGFPEEMIHQALLTAVYAAREQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPRENDSMMVRWASRAFFTELLNAGVKIYQFEGGLLHSKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSALLDGELWNKRPLWHRVTERLFYFFSPLL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cls mutant is attenuated in mice (Mecsas et al., 2001).
COG COG1502I, under I: Lipid transport and metabolism
References
Mecsas et al., 2001: Mecsas J, Bilis I, Falkow S. Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis. Infection and immunity. 2001; 69(5); 2779-2787. [PubMed: 11292689].