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FTL_0899

Victor ID 415
Gene Name FTL_0899
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3950948
NCBI Protein GI 89256256
Locus Tag FTL_0899
Protein Accession YP_513618.1
Taxonomy ID 119857
Gene Starting Position 877316
Gene Ending Position 878623
Gene Strand (Orientation) +
Protein Name protease, GTP-binding subunit
DNA Sequence 
>gi|89255449:877316-878623 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
GATGGAATTTTTCCAATCGTATCAAGCAGGTAGTAAGTGCCTGCTTGTAAATATAAATTTCAAATATCAT
CGTGAACTTAATCCTGATTTAACAGAGTTGGAAGGCTTAGTTATAGCAGCAGAAAAAGTTGTATTGCAAG
GTTTAGATTTTAACCATCCTGAGCCAGATATCAAATACTTTTGCGGTATGGGTAAAATCGAAATGATTAA
AAATAAACGCGATGAACTAGAAGCAGATTTAGTTGTTTTTAACCACCCTTTAACTCCCTCTCAAGAACGT
AATATTGAGAAATTTCTTGAGTGCAGAGTTATGGATAGAACTAGATTAATTCTAGAGATATTTTCATTAC
GTGCTAAAACTTATGAGGGTAAACTTCAGGTTGAGTTAGCACAGCTTAACTATCAATCAACACGTTTAGT
CAAAGGATGGACTCACTTAGAGCGACAAAAGGGTGGTATTGGTGTACGTGGTGGACCTGGTGAGACACAG
CTTGAGATAGACAGACGTTTAATTAGACAGAGGATTAAGCAGATTGCACAAAAGCTTGAGAAAGTAAAAC
ATCATCGTGATTTAAGTAGATCTTCGCGTAAAAAAAATAACATTCCAACTATTTCATTTGTGGGATATAC
GAATGCAGGTAAATCAACTTTATTTAATAAAATCACAAATGCTGATGTTTTAGCTAAAGATCAGTTGTTT
GCGACTTTAGATCCTACTTTGCGTAAAGTAATCGTACCTAAACTCGGTGAGATTATATTCTCAGATACTG
TAGGCTTTATCAAAAATTTACCACATAATTTAGTTGAAGCTTTTCATGCTACTTTAGAAGAGGCTATAGA
GTCTGATCTTTTGGTACATGTTATAGATTATGCTGACGAGGATCATAAAAGCTACATTGAGCAGGTTGAA
AAAGTACTCAGTGAAATTGGTATAGCAGACAAAGAGACGATTTGTGTCTATAACAAAATTGATAAATTAG
AAAATATCAAGCCAAGTTTCGTGCCTCTTGAGGATTCTGATAGTAGCGTAGTTAGTAGGGTATATTTATC
TGCACAAAATGGAGATGGTTTAGTAGAGTTTTATCAAGCATTAGCTACATTTTTTAATAAAACATGGATA
AATCAAACTCTAGACTTACCGCCTAAATACTCAAAAGTCAGAGCTAAGATGTATGAGCTTGGTGTTATTG
ATAAAGAAGAGATTTCAGAACACGGTAACTATCTATTACAAATAAAAATATCACAAGATGATTTCGAGAG
ATTTAAAAGGGAACTTAATTTAGATTTAGAAGAGTTCTTCGTTAAATA
Protein Sequence 
>gi|89256256|ref|YP_513618.1| protease, GTP-binding subunit [Francisella tularensis subsp. holarctica LVS] MEFFQSYQAGSKCLLVNINFKYHRELNPDLTELEGLVIAAEKVVLQGLDFNHPEPDIKYFCGMGKIEMIKNKRDELEADLVVFNHPLTPSQERNIEKFLECRVMDRTRLILEIFSLRAKTYEGKLQVELAQLNYQSTRLVKGWTHLERQKGGIGVRGGPGETQLEIDRRLIRQRIKQIAQKLEKVKHHRDLSRSSRKKNNIPTISFVGYTNAGKSTLFNKITNADVLAKDQLFATLDPTLRKVIVPKLGEIIFSDTVGFIKNLPHNLVEAFHATLEEAIESDLLVHVIDYADEDHKSYIEQVEKVLSEIGIADKETICVYNKIDKLENIKPSFVPLEDSDSSVVSRVYLSAQNGDGLVEFYQALATFFNKTWINQTLDLPPKYSKVRAKMYELGVIDKEEISEHGNYLLQIKISQDDFERFKRELNLDLEEFFVK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0899 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG2262R, under R: General function prediction only
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].