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FTL_0894

Victor ID 414
Gene Name FTL_0894
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3950943
NCBI Protein GI 89256251
Locus Tag FTL_0894
Protein Accession YP_513613.1
Taxonomy ID 119857
Gene Starting Position 871671
Gene Ending Position 873995
Gene Strand (Orientation) +
Protein Name DNA-binding, ATP-dependent protease La
DNA Sequence 
>gi|89255449:871671-873995 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGTCAGAACCCCTAAATGTCGTTCCTGTTATTCCTTTAAGAGATGTTGTTATTTATCCATCGATGACT
CTACCACTTAATGTTGGGCGTAAAAAGTCAATAGAGGCAGTTAAACAGGCATCAAATAATTATAATAACT
ATATTTTATTAGCTACACAAAAAAATGGTTCGAGTGGCGGTGATGTTGTAGAAAATATATATGATATTGC
AACTCTTGCTAAAGTTGTTCAGATAATGAAACTTCCTGATGGTAGTCTGAAAATAATAGTCGAGGGTATT
GCTAAAAGACTAGTAGCTAAGTATGAAGATATTGATGGTTGTATCTATGCAAATTTAGATAGTTTACATA
TTGATGATAACTATGATCCCAGCCAAGTTGATAAAGAACTAAAAGCTATTTTACTATCAGTTTCTGATTC
GCTTAAAAGATTTGTTGATATCAGTGGTAGAGTTTCGAAAGAATCATTAGCTACATTGATAAATACGGAA
GAGCCACATAAATTTATTTATGAAATAGCTACTATACTTAATACAGAAATAGCTAAAAAACAAAAAATCC
TTGAGGCAACGGATATAAAAAATAAAGCCTTGCTACTACTTTCATATCTTTATGAAGAGCTAGAGATACT
AGAGCTAGAAGCTAAGATCAAAGATAGAGTCAAAGCTCAAGTTGATAAGAATCAGCGTGAATACTATCTA
AATGAGCAAGTCAAAGCGATATATAAAGAGCTTGGTGAAGCTGATGAAGAATCAGAAGTATCTGTTTTGA
AAAAAAGGATTGAGCATACTAAGATGTCTAAAGAGGCAAAAGAGAAATGCTTAAAAGAGCTCAAGAAACT
TAAGGCTATGCCGCCTTCTTCATCAGAATCAGCTGTTTCGAGAAACTATATTGAAACTATACTTTCTCTA
CCATGGGGTAAGAGGGCAAAAGTTAAAAGAGATATTAATCTTGCTGAGAAAGTTTTAGAAAAAGATCATT
ACGGTATCAAAAAAGTTAAAGAAAGGATCCTTGAGCATTTAGCTGTTCAGATTAAAAGAGACAGTAATAC
TAAAGCACCAATTCTGTGCTTAGTAGGACCTCCAGGAGTAGGTAAAACATCTATAGGACAGTCGATTGCT
AGAGCAACAGGGCGTGAGTATGTGCGTATGGCTTTAGGTGGTGTACGTGATGAGTCTGAGATTAGGGGAC
ATCGTCGTACATACATAGGTTCTATGCCTGGTCAAATTATCCAAAAGATAATTAAATCAAAGACAGAGAA
TCCACTTTTCTTATTAGACGAGATTGATAAAATTTCTTCTGATTTCCGTGGTGATCCATCTGCCGCGCTC
TTAGAAGTACTTGATCCAGAGCAAAATAGTACATTTAACGATCATTACCTTGAGATAGACTATGATTTAT
CAAAGGTAATGTTTGTTGCTACAGCAAATTCCTTAGATATAGATCCAGCATTACGTGATAGATTAGAGAT
TATCAACTTATCAGGCTATACCGAAATAGAGAAGCAAGCTATCGCAAAACAGTATTTAATACCTAAAGCA
TTAGAAAATAATGGTTTGACTAAGGATGAAATTAATTTCACACCAAAAGCTATCCTTGATATTATCAGAT
ATTATACAAGAGAGGCTGGTGTAAGAAATCTTCAGCAAAAAATAGATGGTGTTTGCCGTAAAGCAGTTAA
AAATCTCTTAAAGGATTCAAATACTGGCAAAATTTCGATTACACAAAAAAATCTCGAAGATTATCTTGGT
GTACATCAGTATGATTATGGTGTTAAAAATGCTAAAGCAAAAGTAGGTCAAGTAACAGGTTTAGCTTGGA
CATCAGTTGGTGGAGAGCTTTTGACTATAGAAGCTCTAGCAATGCCAGGAAAAGGTAAAGTTAAATATAC
TGGTAGTCTTGGTGATGTAATGAAAGAATCTATAGATGCTGCTTTTAGTGTGGTACGCTCAATGTCAAAA
GACTATAAGTTAGAAGATGATTTCTATGAGAAAAAAGATATACATATTCATGTCCCTGAAGGAGCTACAC
CAAAAGATGGTCCAAGTGCTGGTATTGCGATGACAACGGCTTTAGTTTCTGTATATACAAACAAACCAGT
TAGAAATGATGTGGCAATGACAGGTGAGGTGACACTCCGTGGTGAAGTGCTAGCTATAGGCGGTTTAAAA
GAAAAGCTTTTGGCAGCATTAAGAGGTGGAATTAAGGAGGTTTTGATCCCAAAACAGAATGTTAAAAATT
TAGCCGATGTTGATAAAGAAATCCTGGAAAAACTCGAAATAACCCCTGTAAGTAGCATAAAAGAGGTTTT
AGAGAGAGTTTTTTG
Protein Sequence 
>gi|89256251|ref|YP_513613.1| DNA-binding, ATP-dependent protease La [Francisella tularensis subsp. holarctica LVS] MSEPLNVVPVIPLRDVVIYPSMTLPLNVGRKKSIEAVKQASNNYNNYILLATQKNGSSGGDVVENIYDIATLAKVVQIMKLPDGSLKIIVEGIAKRLVAKYEDIDGCIYANLDSLHIDDNYDPSQVDKELKAILLSVSDSLKRFVDISGRVSKESLATLINTEEPHKFIYEIATILNTEIAKKQKILEATDIKNKALLLLSYLYEELEILELEAKIKDRVKAQVDKNQREYYLNEQVKAIYKELGEADEESEVSVLKKRIEHTKMSKEAKEKCLKELKKLKAMPPSSSESAVSRNYIETILSLPWGKRAKVKRDINLAEKVLEKDHYGIKKVKERILEHLAVQIKRDSNTKAPILCLVGPPGVGKTSIGQSIARATGREYVRMALGGVRDESEIRGHRRTYIGSMPGQIIQKIIKSKTENPLFLLDEIDKISSDFRGDPSAALLEVLDPEQNSTFNDHYLEIDYDLSKVMFVATANSLDIDPALRDRLEIINLSGYTEIEKQAIAKQYLIPKALENNGLTKDEINFTPKAILDIIRYYTREAGVRNLQQKIDGVCRKAVKNLLKDSNTGKISITQKNLEDYLGVHQYDYGVKNAKAKVGQVTGLAWTSVGGELLTIEALAMPGKGKVKYTGSLGDVMKESIDAAFSVVRSMSKDYKLEDDFYEKKDIHIHVPEGATPKDGPSAGIAMTTALVSVYTNKPVRNDVAMTGEVTLRGEVLAIGGLKEKLLAALRGGIKEVLIPKQNVKNLADVDKEILEKLEITPVSSIKEVLERVF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0894 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0466O, under O: Posttranslational modification, protein turnover, chaperones
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].