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gmd from Yersinia pseudotuberculosis IP 31758

Victor ID 4096
Gene Name gmd from Yersinia pseudotuberculosis IP 31758
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis IP 31758
NCBI Gene ID 5385392
NCBI Protein GI 153950334
Locus Tag YpsIP31758_3041
Protein Accession YP_001402001.1
Other Database IDs UniProtKB-ID: A7FL73_YERP3
UniRef100: UniRef100_A7FL73
UniRef90: UniRef90_A7FL73
UniRef50: UniRef50_O60547
UniParc: UPI00000B8174
EMBL: CP000720
EMBL-CDS: ABS49290.1
RefSeq_NT: NC_009708.1
GenomeReviews: CP000720_GR
KEGG: ypi:YpsIP31758_3041
eggNOG: COG1089
HOGENOM: HBG755066
OMA: TQRVDHI
ProtClustDB: CLSK928700
BioCyc: YPSE349747:YPSIP31758_3041-MONOMER
Taxonomy ID 349747
Gene Starting Position 3423706
Gene Ending Position 3424827
Gene Strand (Orientation) -
Protein Name GDP-mannose 4,6-dehydratase
DNA Sequence 
>gi|153946813:3423706-3424827 Yersinia pseudotuberculosis IP 31758, complete genome
ATTAATTCTCCAACGAAATGGATACGTCAAAGCCATTAGCCTTTAACAATGCATGCTGTTTAGCCTGCTC
TAAGTCACTAGCGACCATTTCAGCACACATTTCTTCAACCGTAATTTCAGGTACCCAGCCTAATACTTTT
TTAGCCTTAGTTGGATCGCCTAATAATGTTTCAACTTCAGCAGGACGGAAATAACGTGGATCAACACGGA
CTATTACATCTCCAATATTGACAGAAGAAATATGGTTACCATTAATAGCAACAACAGTGGCAACCTCTTC
AACGCCTTCTCCACTAAATTCCAATTCAATCCCTGCTTCTCTTGCTGACATACGTACAAACTCACGAACG
GTAATTTGCTTGCCTGTTGCAATAACAAAATCTTCTGGCTTATCTTGTTGCAACATCATCCATTGCATAC
GCACATAATCTTTCGCATGGCCCCAGTCACGTAGCGAATCTATATTGCCTAAATAGAGACATTTTTCTAG
ACCTAATGCAATATTCGCAACAGCACGGGTAATCTTCCGAGTAACAAATGTTTCACCACGACGAGGAGAC
TCATGGTTAAATAAAATTCCGTTACAAGCATACATTCCATATGATTCACGGTAATTTACTGTAATCCAGT
AAGCATACATTTTGGCAACAGCATAAGGAGAACGCGGATAGAATGGCGTTGTTTCACGCTGAGGCGTTTC
CTGCACTAAACCATAAAGCTCTGAGGTTGAGGCTTGATAGAAACGAGTCTTCTTTTCAAGCCCATTGATA
CGAATGGCCTCTAGCAACCGCAGTGTCCCCATGGCATCAACATCGGCAGTATATTCCGGTGATTCAAATG
AAACAGCCACATGAGATTGTGCACCCAAATTATAAATCTCATCAGGCTGAATTTCCTGGACCAAACGAAT
TAAATTCGACGTGTCAGTCAAGTCACCATAATGTAAAAAGAAGCGTGGATTCGTCTCATGGCGATCTTGA
TAAATATGATCAATGCGGCTGGTATTAAAAGATGAAGCTCGGCGCTTAATACCATGAACCTCATAACCCT
TTTCTAATAAAAACTCAGCCAAATAAGAGCCATCTTGTCCTGTAATACCAGTAATGAGCGCAATCTTAGT
CA
Protein Sequence 
>gi|153950334|ref|YP_001402001.1| GDP-mannose 4,6-dehydratase [Yersinia pseudotuberculosis IP 31758] MTKIALITGITGQDGSYLAEFLLEKGYEVHGIKRRASSFNTSRIDHIYQDRHETNPRFFLHYGDLTDTSNLIRLVQEIQPDEIYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAIRINGLEKKTRFYQASTSELYGLVQETPQRETTPFYPRSPYAVAKMYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAVANIALGLEKCLYLGNIDSLRDWGHAKDYVRMQWMMLQQDKPEDFVIATGKQITVREFVRMSAREAGIELEFSGEGVEEVATVVAINGNHISSVNIGDVIVRVDPRYFRPAEVETLLGDPTKAKKVLGWVPEITVEEMCAEMVASDLEQAKQHALLKANGFDVSISLEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gmd mutant is attenuated in mice (Mecsas et al., 2001).
COG COG1089M, under M: Cell wall/membrane/envelope biogenesis
References
Mecsas et al., 2001: Mecsas J, Bilis I, Falkow S. Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis. Infection and immunity. 2001; 69(5); 2779-2787. [PubMed: 11292689].